Sub-strand 2: Metabolomic/Proteomic Research towards Improved Animal Health and Food Assurance
Researchers at Queen's University have in recent times pioneered techniques for developing targeted and untargeted ‘fingerprinting' analytical approaches to food safety. Sub-Strand 2 of ASSET applies post-genomic advanced metabolomic / proteomic analysis of the dynamic effects of chemical / biological exposure in living systems and applies observations to efforts to ensure food chain integrity and animal welfare.
Sub-Strand 2 of ASSET will aim to apply novel metabolomic/proteomic strategies in areas of research related to:
ASSET has recently acquired a state-of-the-art UPLC–qTOF MS instrument to assist in metabolomic/proteomic research activities.
The Xevo G2 QTof mass spectrometer, with UPLC®/MSE and QuanTof technology, offers exceptional levels of sensitivity, selectivity, in-spectrum dynamic range, speed of analysis, quantitative accuracy and exact mass performance simultaneously for any experiment, whether UPLC/MS, MSE or MS/MS. It also delivers UPLC/FastDDA: rapid, automated, intelligent exact mass MS/MS for targeted qualitative analyses as well as isobaric labeling quantitative proteomics experiments.
NMR Metabolomic Profiling Techniques
Peer reviewed scientific papers relating to Proteomic/Metabolomic activities of ASSET can be accessed below:
Studies on the persistence of estradiol benzoate and nortestosterone decanoate in hair of cattle following treatment with growth promoters, determined by ultra-high-performance liquid chromatography-tandem mass spectrometry
For further information relating to Proteomic/Metabolomic research activities within ASSET please contact Dr Mark Mooney.
ASSET Proteomic/Metabolomic Research Collaborating Partners