Staff Profile




General Profile Information
Staff Name Professor Louise Cosby
Job Title Professor
Location Medical Biology Centre Block 97 Health Sciences
Room Number 04.033
School School of Medicine, Dentistry and Biomedical Sciences
Contact Details
Telephone +44 (0)28 9097 2258
E-mail l.cosby@qub.ac.uk
Interests
The research focus is on elucidation of pathogenic mechanisms of morbilliviruses and related virus infections as well as characterization of new virus isolates. A major interest is in the interaction of viruses with cell receptors (with particular emphasis on neural cell and airway receptors) as major determinants of virus host range, tissue tropism and induction of disease. 



Teaching

Co-ordination, course development and teaching Medical Microbiology and Immunology to Medical and Dental students.

Co-orgination, course development and teaching of Virology to science students.

Aspects of Molecular biology are taught  (plus course development and co-ordination of Molecular medicine course) to these different student groups.

Co-ordination of Infection control session for final year Medical Students.





Research Keywords
Viruses Measles virus Microbiology seal virus



Other Information

Recent Invited Lectures

2010 - University of University of Manchester
2010 - University of Liverpool
2010 - Institute of Animal Health, Pirbright
2010 - University of Nantes, France
2010 - Therapeutic Antibodies Europe Conference
2010 - European Measles Virus Meeting, Wurzburg





Publications
Authored Book(s)
TitlePublisherYear
Rinderpest and Pestes des Petits Ruminants Academic Press, Elsevier 2006
Journal(s)
TitleJournal NameYear
Phocine distemper virus in seals, east coast, United States, 2006 Emerging Infectious Diseases Vol 17 (215-220)  DOI   2011
Transcriptional upregulation of SOCS 1 and suppressors of cytokine signaling 3 mRNA in the absence of suppressors of cytokine signaling 2 mRNA after infection with West Nile virus or tick-borne encephalitis virus. Vector Borne & Zoonotic Diseases Vol 10(7) (649-653)  DOI   2010
Persistent measles virus infection of mouse neural cells lacking known human entry receptors. Journal of Neuropathology and Applied Neurobiology Vol 35(5) (473-486)  DOI   2009
Herpes simplex virus type 1 and Alzheimer's disease: the autophagy connection. Journal of NeuroVirology Vol 14(1) (1-4)  DOI   2008
Advantages of using recombinant measles viruses expressing a fluorescent reporter gene with vibratome slice technology in experimental measles neuropathogenesis. Journal of Neuropathology and Applied Neurobiology Vol 34(4) (424-434)  DOI 2008
Measles virus and classical Hodgkin lymphoma: no evidence for a direct association. International journal of cancer. Journal international du cancer Vol 121(2) (442-447)  DOI 2007
Advantages of using recombinant measles viruses expressing a fluorescent reporter gene with vibratome slice technology in experimental measles neuropathogenesis Neuropathology and Applied Neurobiology Vol 33 (---)  DOI 2007
Measles virus and classical Hodgkin lymphoma: No evidence for a direct association International Journal of Cancer Vol 121(2) (442-447)  DOI 2007
Measles virus superinfection immunity and receptor redistribution in persistently infected NT2 cells Journal of General Virology Vol 86(8) (2291-2303)  DOI   2005
Inhibition of host peripheral blood mononuclear cell proliferation ex vivo by Rinderpest virus Journal of General Virology Vol 86(12) (3349-3355)  DOI 2005
Comparative evaluation of measles virus-specific RT-PCR methods through an international collaborative study. Journal of Medical Virology Vol 70(1) (171-176)  DOI 2003
Rinderpest and peste de petits ruminants viruses exhibit neurovirulence in mice Journal of NeuroVirology Vol 8(1) (45-52)  DOI   2002
Inhibition of In Vitro Leukocyte Proliferation by Morbilliviruses Journal of Virology Vol 76(7) (3579-3584)  DOI 2002
An Immunohistochemical Study of the Distribution of the Measles Virus Receptors, CD46 and SLAM, In Normal Human Tissues and Subacute Sclerosing Panencephalitis Laboratory Investigation Vol 82 (4) (403-409)    2002
Other Output(s)
TitlePublication TypeYear
Advantages of using recombinant measles viruses expressing a fluorescent reporter gene with vibratome slice technology in experimental measles neuropathogenesis Internet publication 2007