Staff Profile

General Profile Information
Staff Name Dr Lorcan McGarvey
Job Title Clinical Senior Lecturer (Cons) (JA)
Location CEM Block 6 MBC Site
Room Number 0G.022
School School of Medicine, Dentistry and Biomedical Sciences
Contact Details
Telephone +44 (0)28 9097 6377
Research Statement

I am currently investigating the expression and functional characteristics of novel ion channels located in the airways of asthmatic and cough patients. It is hoped this work will help identify novel targets for the treatment of acute and chronic cough. I have been a core contributor to one national (British Thoracic Society, 2006) and two international (European Respiratory Society, 2004 & 2007) guideline documents on cough which have pioneered the clinical and scientific approach to this field of respiratory medicine.

In collaboration with Wise (Johns Hopkins Hospital, Baltimore, USA) and John (Charite Hospital, Berlin, Germany) I have developed a new methodological approach to the reliable adjudication of cause-specific mortality in chronic obstructive pulmonary disease (COPD). This methodology has been utilised in the two largest clinical trials in COPD to date (TORCH & UPLIFT).

In 2008 I established the Premature Adult Lung Study (PALS) group, a multidisciplinary team currently undertaking a programme of research to comprehensively evaluate the impact of bronchopulmonary dysplasia (BPD) in adult life.

Professional Qualifications
Clinical Lead for NI Clinical Research Network (Respiratory Health) and Committee member on UKCRN/NIHR Respiratory Specialty Group. (Appointed 2008)



Committee Membership

Co-Chairman British Thoracic Society (BTS) Cough Guideline Group (2004-present)

Panel Member of the European Respiratory Society (ERS) Cough Taskforce (2003-present)

Member of the Scientific Organising Committee for the International Society for the Study of Cough   (ISSC) (2006-present)

Chairman of Mortality Adjudication Committee for UPLIFT, a global multi-centre 4 year study of long     acting anti-cholinergic therapy on lung function in COPD

Member of Clinical Endpoint Committee for TORCH, a global multi-centre 3 year mortality study in COPD

Clinical Lead for NI Clinical Research Network (Respiratory Health) (Appointed 2007)

Committee member on UKCRN/NIHR Respiratory Specialty Group. (Appointed 2008)

Member of Scientific Research Committee (Grant Award Committee) for Northern Ireland Chest Heart & Stroke (2006-present)

Editorial Board for Cough and Journal of Occupational Medicine and Toxicology.



MD/PhD External Examiner

University of Sydney

University College Cork

Katholieke Universiteit Leuven

University of Salford

University of Hull

University of Leicester



Journal Review

American Journal Respiratory Critical Care Medicine


European Respiratory Journal


Respiratory Medicine

Pulmonary Pharmacology & Therapeutics

Cough (Editorial Board)

Journal of Occupational Medicine & Toxicology



Grant Review

Medical Research Council

NI Chest Heart & Stroke


Membership Of Other Societies / Professional Activities
Invited Lectures at National & International Meetings 2009-2010 :


1. Airway Nerves in Reflux & Aspiration: 8th International Symposium on Human Pepsin (ISHP). Milwaukee, Wisconsin, USA.  September 2008


2. Understanding the New Evidence in COPD. COPD Respiratory Summit, Manila, Philipines. March 2009


3. Cough: A Clinical Year in Review. 2nd American Cough Conference, New York, NY, USA. June 2009


4. Can Patients Quality of Life be improved with Treatment? COPD Masterclass. 14th Asia Pacific  Society of Respirology Meeting. Seoul, South Korea. November 2009


5. Chronic Cough. VIth CYNA Allergy Meeting, Madrid January 2010


6. Cough and Reflux.  9th International Symposium on Human Pepsin. Hull, UK, April 2010


7. Clinical Patterns of Cough.  6th International Symposium on Cough, London. June 2010


8. GORD induced cough. ERS Postgraduate Course, Barcelona. September 2010


TitleJournal NameYear
The Effect of Rhinovirus Infection on Cough Receptors on Airway Sensory Nerves Journal of NeuroVirology Vol 16 (1-1)  2010
The Differential Effect of Gastroesophageal Reflux Disease on Mechanostimulation and Chemostimulation of the Laryngopharynx Chest Vol 138 (1180-1185)  DOI   2010
Nonacid reflux episodes reaching the pharynx are important factors associated with cough. Journal of Clinical Gastroenterology Vol 43(5) (414-419)  DOI   2009