Staff Profile


Publications
Edited Book(s)
TitlePublisherYear
Difficult Asthma Jaypee Brothers Medical Publishers 2011
Chapter(s)
TitleBook TitleYear
Inflammation in chronic obstructive pulmonary disease: Implications for new treatment strategies Inflammatory Diseases 2011
Difficult Asthma Asthma 2011
Refractory Asthma – the patient’s perspective Difficult Asthma 2011
Non-adherence in Difficult Asthma Difficult Asthma 2011
Difficult Asthma Asthma 2008
Journal(s)
TitleJournal NameYear
Increased expression of immunoreactive thymic stromal lymphopoetin in severe asthma Journal of Allergy and Clinical Immunology Vol epub October 2011  2012
Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells. Virology journal Vol 8 (43-  DOI   2011
A study of a multi-level intervention to improve non-adherence in difficult to control asthma. Respiratory Medicine Vol 105(9) (1308-1315)  DOI 2011
Non-adherence in difficult asthma: time to take it seriously. Thorax Vol epub (1308-1315)  DOI 2011
The Utility of Cardiopulmonary Exercise Testing in Difficult Asthma. Chest Vol 139(5) (1117-1123)  DOI 2011
The impact of non-adherence to inhaled long-acting β2-agonist / steroid combination therapy on healthcare costs in difficult to control asthma Pharmaceutical Medicine Vol in press (1117-1123)  2011
Effects of interleukin-13 on mucociliary differentiation of paediatric asthmatic bronchial cells. Pediatric Research Vol 69 (2) (95-100)  DOI   2011
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma. Thorax Vol ePub (95-100)  DOI 2011
Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry. Thorax Vol 65(9) (787-794)  DOI   2010
The safety of bisphosphonate use in pre-menopausal women on corticosteroids. Current Drug Safety Vol 5(2) (182-187)  2010
Respiratory viral infection in lower airways of asymptomatic children. Acta paediatrica (Oslo, Norway : 1992) Vol 99(3) (394-398)  DOI   2010
Cytopathogenesis of Sendai virus in well-differentiated primary pediatric bronchial epithelial cells. Journal of Virology Vol 84 (11718-11728)  DOI   2010
A Large-Scale, Consortium-Based Genomewide Association Study of Asthma New England Journal of Medicine Vol 363(13) (1211-1221)  2010
A 3-D well differentiated model of pediatric bronchial epithelium demonstrates unstimulated morphological differences between asthmatic and nonasthmatic cells Pediatric Research Vol 67 (17-22)  DOI   2010
Difficult to treat asthma in adults British Medical Journal Vol 24 (338-b494)  DOI 2009
The prevalence of nonadherence in difficult asthma American Journal Respiratory Critical Care Medicine Vol 180 (817-822)  DOI   2009
Omalizumab: the evidence for its place in the treatment of allergic asthma. Core Evidence Vol 3(1) (55-66)  DOI   2008
Impact of cough across different chronic respiratory diseases: comparison of two cough-specific health-related quality of life questionnaires Chest Vol 134 (2) (295-302)  DOI   2008
Neurogenic inflammation in asthma Current Drug Targets. Inflammation and Allergy Vol 6(2) (127-132)  2007
Difficult asthma: people's perspectives on taking corticosteroid therapy Journal of Clinical Nursing Vol 16(3A) (59-67)  2007
Acute and latent adenovirus in COPD Respiratory Medicine Vol 101(10) (2084-2090)  2007
Airway expression of calcitonin-gene related peptide in T-cell peptide induced late asthmatic reactions in atopics Allergy Vol 62(5) (495-503)  2007
Inflammation in chronic obstructive pulmonary disease - implications for new treatment strategies Current Medical Chemistry Vol 14(7) (787-796)  2007
Assessment of impairment in health-related quality of life in patients with difficult asthma: psychometric performance of the asthma quality of life questionnaire Respirology Vol 12(2) (227-233)  2007
Increased tachykinin levels in induced sputum from asthmatic and cough patients with acid reflux Thorax Vol 62 (491-495)  DOI 2007
A cross-sectional study evaluating the relationship between cortisol suppression and asthma control in patients with difficult asthma British Journal of Clinical Pharmacology Vol 63(1) (110-115)  DOI 2007
Prevalence of psychomorbidity among patients with chronic cough Cough (London, England) Vol 16 (2(1)-4)  2006
A comparison of direct medical care costs among COPD and asthma patients living in the community in Northern Ireland Treatments in Respiratory Medicine Vol 5(6) (495-501)  2006
Severe asthma treatment: need for characterising patients The Lancet Vol 365(9463) (974-976)  DOI 2005
Prevalence of gastroesophageal reflux in difficult asthma - Relationship to asthma outcome Chest Vol 127(4) (1227-1231)  DOI 2005
Prevalence of psychiatric morbidity in a difficult asthma population: Relationship to asthma outcome Respiratory Medicine Vol 99 (1152-1159)  2005
Short burst oxygen therapy in chronic obstructive pulmonary disease: a patient survey and cost analysis International Journal of Clinical Practice Vol 59 (751-753)  2005
Relationship between lung function and asthma symptoms in patients with difficult to control asthma Journal of Asthma Vol 42 (859-864)  2005
Endobronchial adenosine monophosphate challenge causes tachykinin release in the human airway Journal of Allergy and Clinical Immunology Vol 116(2) (312-317)  DOI 2005
Children with stable asthma have reduced airway matrix metalloproteinase-9 and matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio Clinical & Experimental Allergy Vol 35(9) (1168-1174)  DOI   2005
The prevalence of obstructive lung disease in a general population sample: the NICECOPD study European Journal of Epidemiology Vol 20 (443-453)  2005
Mass cell mediator release in non-asthmatic subjects after endobronchial adenosine challenge Journal of Allergy and Clinical Immunology Vol 114(1) (34-39)  2004
Adenosine, inflammation and asthma - a review Inflammation research : official journal of the European Histamine Research Society ... [et al.] Vol 53(5) (171-178)  2004
A possible case of pneumoconiosis in a limestone quarry worker Occupational Medicine - Oxford Vol 54 (497-499)  2004
Oesophageal pH monitoring is of limited value in the diagnosis of European Respiratory Journal Vol 24 (724-727)  2004
Prescribing practice for intermittent oxygen therapy: a GP survey Chronic Respiratory Disease Vol 1 (139-142)  2004
Psychogenic cough in a schoolboy: Evaluation using an ambulatory cough recorder Pediatric Pulmonology Vol 36 (73-75)  2003
Predictors of therapy resistant asthma: outcome of a systematic evaluation protocol Thorax Vol 58(7) (561-566)  DOI 2003
Simple liquid chromatography method for the rapid simultaneous determintion of prednisolone and cortisol in plasma and urine using hydrophilic lipophilic balanced solid phase extraction cartridges Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences Vol 798 (193-201)  2003
Non-bronchoscopic sampling and culture of bronchial epithelial cells in children Clinical & Experimental Allergy Vol 33(9) (1221-1225)  DOI 2003
Nasal septal perforation and oxygen cannulae Hospital Medicine Vol 62 (248-248)  2001
Progressive breathlessness in an 18 year old male - idiopathic pulmonary emphysema Postgraduate Medical Journal Vol 76 (307-307)  2000
Eosinophilic bronchitis is an important cause of chronic cough American Journal of Respiratory Critical Care Medicine Vol 161 (1763-1764)  2000
Sensory neuropeptides induce histamine release from bronchoalveolar lavage cells in both nonasthmatic coughers and cough variant asthmatics Clinical & Experimental Allergy Vol 30 (225-232)  2000
Is there an association between angiotensin-converting enzyme gene variants and chronic nonproductive cough Chest Vol 118 (1091-1094)  2000
Adenosine stimulates histamine release from human bronchoalveolar lavage cells Clinical Science Vol 96 (349-355)  1999
Inflammatory mediators in bronchoalveolar lavage samples from children with and without asthma Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Vol 29 (362-366)  1999
Domicilary Oxygen Provision - are the drug tariff prescribing guidelines cost effective British Medical Journal Vol 319(7201) (19-23)  1999
A retrospective survey of diagnosis and management of patients presenting with chronic cough to a general chest clinic. International Journal of Clinical Practice Vol 52(3) (158-161)  1998
Histamine release from bronchoalveolar lavage cells from asthmatic subjects after allergen challenge and relationship to development of a late asthmatic response Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Vol 1998 (196-204)  1998
Neurokinin A is the predominant tachykinin in human bronchoalveolar lavage fluid in normal and asthmatic subjects Thorax Vol 53 (357-362)  1998
Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol Thorax Vol 53 (738-743)  1998
Evidence for ongoing airways inflammation in the subjects with chronic non-productive cough European Respiratory Journal Vol 13 (59-65)  1998
Neurokinin A and bradykinin stimulate human pulmonary mast cells Inflammation research : official journal of the European Histamine Research Society ... [et al.] Vol 46 (304-309)  1997
Bronchoalveolar lavage findings suggest two different forms of childhood asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Vol 27(9) (1027-1035)  1997
A comparison of three standard methods of identifying mast cells in endobronchial biopsies in normal and asthmatic subjects. Allergy Vol 52(8) (836-843)  1997
Dyspnoea, anorexia and weight loss in a 74 year old man. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology Vol 10(6) (1412-1414)  1997
Brewer's asthma due to malt contamination. Occupational medicine (Oxford, England) Vol 47(7) (397-400)  1997
Prescription of oxygen concentrators and survival in Northern Ireland. The Ulster Medical Journal Vol 66(2) (86-91)  1997
Further characterisation of SP-induced histamine release from human bronchoalveolar lavage cells Inflammation Research Vol 45 (11-13)  1996
Investigating paediatric airways by non-bronchoscopic lavage: normal cellular data. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Vol 26(7) (799-806)  1996
Substance P causes histamine release from bronchoalveolar lavage mast cells Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Vol 25 (179-186)  1995
Electronic cell counting to assess cell numbers in bronchoalveolar lavage fluid European Respiratory Journal Vol 7 (1527-1531)  1994
Differential reactivity of bronchial lavage mast cells to substance P Agents and actions Vol 41 (19-21)  1993