Staff Profile




General Profile Information
Staff Name Dr Rebecca Ingram
Job Title Lecturer
Location H.S.B Block 10 MBC Site
Room Number 01.021
School School of Medicine, Dentistry and Biomedical Sciences
Contact Details
Telephone +44 (0)28 9097 2090
E-mail b.ingram@qub.ac.uk
Research Keywords
immunology T cell Treg infection in vivo model



Research Statement

My main research focus is the interface between the innate and adaptive immune response to bacterial infections.  I am working on the development of in vivo models of acute and chronic lung disease.  These models extensively utilise both GM bacteria that have been stably transfected resulting in them bioluminesing (collaboration University of Auckland and Imperial College) and murine transgenics engineered so that specific immune cell subpopulations are either fluorescent or bioluminescent (collaboration Imperial College).  The models generated in this project will then be exploited by in order to complement the internationally recognised patient based research currently undertaken within the Respiratory group of the Centre for Infection and Immunity. 





Publications
Journal(s)
TitleJournal NameYear
The nature of innate and adaptive IL-17A responses in sham or bacterial inoculation Immunology Vol 0  DOI   2012
Comment on ‘Frequency of Naïve CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire Journal of Immunology Vol 188(11) (5205-5206)  DOI 2012
Repertoire of HLA-DR1-restricted CD4 T cell responses to capsular Caf1 antigen of Y. pestis HLA-transgenic mice Infection and Immunity Vol 78 (10) (4356-4362)  DOI   2010
An epitope of B. anthracis proptective antigen that is cryptic in rabbits may be immunodominant in man Infection and Immunity Vol 78 (5) (2353-2354)  DOI 2010
Natural Exposure to Cutaneous Anthrax Gives Long-Lasting T Cell Immunity Encompassing Infection-Specific Epitopes Journal of Immunology Vol 184 (3814-3821)  DOI   2010
An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor Vaccine Vol 28 (41) (6740-6748)  DOI   2010
A role of cellular prion protein in programming T-cell cytokine responses in disease. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology Vol 23(6) (1672-1684)  DOI   2009
The human prion protein residue 129 polymorphism lies within a cluster of epitopes for T cell recognition. Journal of neuropathology and experimental neurology Vol 65(11) (1059-1068)  DOI   2006
Expression of the common heat-shock protein receptor CD91 is increased on monocytes of exposed yet HIV-1-seronegative subjects. Journal of Leukocyte Biology Vol 78(1) (37-42)  DOI   2005
Distinct patterns of peripheral HIV-1-specific interferon- gamma responses in exposed HIV-1-seronegative individuals. The Journal of Infectious Diseases Vol 189(9) (1705-1713)  DOI   2004
Penetration of human skin by the cercariae of Schistosoma mansoni: an investigation of the effect of multiple cercarial applications. Journal of Helminthology Vol 77(1) (27-31)  DOI   2003
Dimethicone barrier cream prevents infection of human skin by schistosome cercariae: evidence from Franz cell studies. The Journal of parasitology Vol 88(2) (399-402)  2002