Staff Profile

Research Statement

My main research focus is the interface between the innate and adaptive immune response to bacterial infections.  I am working on the development of in vivo models of acute and chronic lung disease.  These models extensively utilise both GM bacteria that have been stably transfected resulting in them bioluminesing (collaboration University of Auckland and Imperial College) and murine transgenics engineered so that specific immune cell subpopulations are either fluorescent or bioluminescent (collaboration Imperial College).  The models generated in this project will then be exploited by in order to complement the internationally recognised patient based research currently undertaken within the Respiratory group of the Centre for Infection and Immunity.