Staff Profile




General Profile Information
Staff Name Dr Conall McCaughey
Job Title Honorary Senior Lecturer
School School of Medicine, Dentistry and Biomedical Sciences
Contact Details
E-mail c.mccaughey@qub.ac.uk
Interests

I am Consultant Virologist in the Belfast Trust and Honorary Senior Lecturer, QUB.  My main interests are in Zoonotic infections and in the development and clinical validation of diagnostic assays in microbiology.

Qualifications:

1983 BSc (Hons) Med Microbiology (intercalated during undergrad medicine); -QUB

1987 MB BCh BAO; -QUB

1994 FRCPath; by examination (Virology) -Royal College of Pathologists

1997 MD; By thesis (Hantaviruses); -QUB





Teaching

Current Teaching:

Undergraduate

  • Medical  undergraduate Phase 2 core curriculum- I deliver 6 lectures and contribute to tutorials and assessment process. I had a key role in the development of the curriculum for his course.
  • Medical undergraduate Phase 2 Student Selected Component (Microbial infection) - I deliver 4 lectures and one seminar and contribute to assessment of this course. I had a key role in the development of the curriculum for his course.
  • Medical undergraduate Phase 3, Science Behind Clinical Practice (SBCP). I coordinate the  microbiology component of this course (12 web based lectures, 3 videos, self assessment exercises). I led the development of the microbiology curriculum for his course and organise the microbiology component of the assessment.
  • Dental 3rd year microbiology course- I deliver virology components (3 lectures and 1 case based scenario session) of this course and contribute to assessment of this course. I expect to be closely involved in the reorganisation of microbiology teaching for dental students and the resulting new second year microbiology course.

Postgraduate

  • Clinical supervisor for microbiology trainees rotating through virology.
  • Member of the Northern Ireland Medical and Dental Training Agency training committee for microbiology.
  • Deliver regular weekly tutorial sessions and other post graduate teaching




Research Statement

My main interests are in Zoonotic infections and in the development and clinical validation of diagnostic assays in microbiology.





Publications
Journal(s)
TitleJournal NameYear
False-positive PCR results linked to administration of seasonal influenza vaccine Journal of Medical Microbiology Vol 61 (332-338)  DOI   2012
Rising incidence of Pneumocystis jirovecii pneumonia suggests iatrogenic exposure of immune compromised patients may be becoming a significant problem. Journal of Medical Microbiology Vol ? (?-?)    2012
Hepatitis A outbreak predominantly affecting men who have sex with men in Northern Ireland, October 2008 to July 2009 EUROSURVEILLANCE Vol 16 (11-16)    2011
Interlaboratory comparison of real-time polymerase chain reaction methods to detect Coxiella burnetii, the causative agent of Q fever Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc Vol 23 (108-111)    2011
Development and clinical validation of multiplex TaqMan(R) assays for rapid diagnosis of viral gastroenteritis Journal of Medical Virology Vol 83 (1650-1656)  DOI   2011
Development and clinical validation of a loop-mediated isothermal amplification method for the rapid detection of Neisseria meningitidis Diagnostic Microbiology and Infectious Disease Vol 69 (137-144)  DOI   2011
Immunovirological Correlates in Human Rabies Treated With Therapeutic Coma Journal of Medical Virology Vol 82 (1255-1265)  DOI   2010
Coxiella burnetii (Q fever) seroprevalence in cattle Epidemiology and Infection Vol 138 (21-27)  DOI   2010
Enhanced reactivity of peripheral blood immune cells to HSV-1 in primary achalasia. Scandinavian Journal of Gastroenterology Vol 45(7-8) (806-813)  DOI 2010
Influenza: a virus of our times. The Ulster Medical Journal Vol 79(2) (46-51)  2010
Human seroprevalence to Coxiella bumetii (Q fever) in Northern Ireland Zoonoses Public Health Vol 55 (189-194)  DOI   2008
Coxiella buvnetii infection of an aortic graft with multiple vertebral body erosion Journal of Vascular Surgery Vol 45 (399-403)  DOI   2007
Association of the G4 rotavirus genotype with gastroenteritis in adults Journal of Medical Virology Vol 78 (1119-1123)  DOI   2006
Lack of association between serological evidence of past Coxiella burnetii infection and incident ischaemic heart disease: nested case-control study. BMC Infectious Diseases Vol 5 (61-1123)  DOI 2005
A touchdown nucleic acid amplification protocol as an alternative to culture backup for immunofluorescence in the routine diagnosis of acute viral respiratory tract infections. BMC Microbiology Vol 4 (41-1123)  DOI 2004
The diagnosis of acute hepatitis C virus infection during seroconversion: an important therapeutic opportunity. The Journal of infection Vol 49(2) (165-168)  DOI 2004
Herpes simplex type 1 shedding is associated with reduced hospital survival in patients receiving assisted ventilation in a tertiary referral intensive care unit. Journal of Medical Virology Vol 72(1) (121-125)  DOI 2004
Real-time nested multiplex PCR for the detection of herpes simplex virus types 1 and 2 and varicella zoster virus. Journal of Medical Virology Vol 71(4) (557-560)  DOI 2003
Genetic characterisation of a Hantavirus isolated from a laboratory-acquired infection. Journal of Medical Virology Vol 71(1) (105-109)  DOI 2003
Emergence of herpes simplex type 1 as the main cause of recurrent genital ulcerative disease in women in Northern Ireland. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Vol 27(1) (22-29)  2003
Clinical assessment of a generic DNA amplification assay for the identification of respiratory adenovirus infections. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Vol 26(3) (331-338)  2003
Clinical utility of nested multiplex RT-PCR for group F adenovirus, rotavirus and norwalk-like viruses in acute viral gastroenteritis in children and adults. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Vol 25(3) (335-343)  2002
A nested primer set targeting the cytomegalovirus glycoprotein B gene. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Vol 25(1) (95-96)  2002
Clinical utility of a nested nucleic acid amplification format in comparison to viral culture for the diagnosis of mucosal herpes simplex infection in a genitourinary medicine setting. BMC Infectious Diseases Vol 1 (11-96)  2001
A comparison of nested polymerase chain reaction and immunofluorescence for the diagnosis of respiratory infections in children with bronchiolitis, and the implications for a cohorting strategy. The Journal of hospital infection Vol 49(2) (122-128)  DOI 2001
Non-detection of Chlamydia species in carotid atheroma using generic primers by nested PCR in a population with a high prevalence of Chlamydia pneumoniae antibody. BMC Infectious Diseases Vol 1 (12-128)  2001
Gastroenteritis outbreaks associated with Norwalk-like viruses and their investigation by nested RT-PCR. BMC Microbiology Vol 1 (14-128)  2001
Nested multiplex polymerase chain reaction for the diagnosis of cutaneous herpes simplex and herpes zoster infections and a comparison with electronmicroscopy. Journal of Medical Virology Vol 63(1) (52-56)  2001
Hantaviruses. Journal of Medical Microbiology Vol 49(7) (587-599)  2000
Rationalised virological electron microscope specimen testing policy. Journal of Clinical Pathology Vol 53(2) (163-599)  2000
Description of a nonlethal herpes simplex virus type 1 glycoprotein D deletion mutant affecting a site frequently used for PCR. Clinical and Diagnostic Laboratory Immunology Vol 7(2) (322-324)  2000
Low pH-induced cytopathic effect--a survey of seven hantavirus strains. Journal of Virological Methods [01660934] Vol 81(1-2) (193-197)  1999
Effect of faecal consistency on virological diagnosis. The Journal of infection Vol 36(2) (145-148)  1998
Nucleotide sequence and phylogenetic analysis of the medium (M) genomic RNA segments of three hantaviruses isolated in China. Virus Research Vol 56(1) (69-76)  1998
Recrudescent herpes simplex infection mimicking primary herpetic gingivostomatitis. Journal of Oral Pathology and Medicine Vol 27(1) (8-10)  1998
Varicella vaccine in pregnancy. Testing should be offered to women without a history of chickenpox. BMJ (Clinical research ed.) Vol 314(7075) (226-10)  1997
Herpes simplex type 1 and genital herpes in Northern Ireland. International Journal of STD & AIDS Vol 8(1) (68-69)  1997
Isolation of viruses from clinical specimens in microtitre plates with cells inoculated in suspension. Journal of Virological Methods [01660934] Vol 62(2) (169-178)  1996
Evidence of hantavirus in wild rodents in Northern Ireland. Epidemiology and Infection Vol 117(2) (361-365)  1996
Serological evidence of Hantavirus disease in Northern Ireland. Journal of Medical Virology Vol 43(1) (33-38)  1994
Antibodies to rubella and human herpesvirus 6 in diverse retinal diseases. The Journal of Infectious Diseases Vol 167(6) (1499-1500)  1993
A simple standardised protocol for the production of monoclonal antibodies against viral and bacterial antigens. Journal of Immunological Methods Vol 153(1-2) (81-84)  1992
Central venous line infection caused by Brevibacterium epidermidis. The Journal of infection Vol 23(2) (211-212)  1991