Staff Profile


Publications
Journal(s)
TitleJournal NameYear
SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. Journal of Experimental Medicine Vol 208 (1523-1531)  DOI   2011
The Deubiquitinating Enzyme USP17 is Essential for GTPase Subcellular localization and Cell Motility Nature Communications Vol 2:259 (1523-1531)  DOI   2011
The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression. Cancer Research Vol 70(8) (3329-3339)  DOI   2010
SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases HAEMATOLOGICA-THE HEMATOLOGY JOURNAL Vol 94 (576-580)  DOI   2009
A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3(F136L)) cannot regulate erythropoietin responses British Journal of Haematology Vol 147 (450-458)  DOI   2009
Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production Journal of Immunology Vol 183(12) (7703-7709)  DOI   2009
USP17 Regulates Ras Activation and Cell Proliferation by Blocking RCE1 Activity Journal of Biological Chemistry Vol 284 (9587-9595)  DOI   2009
Substitution of pseudokinase domain residue Val-617 by large non-polar amino acids causes activation of JAK2 Journal of Biological Chemistry Vol 283 (12941-12948)  DOI   2008
The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3 Blood Vol 109(11) (4924-4929)  DOI   2007
CD33 reponses are blocked by SOCS3 through accelerated proteasomal-mediated turnover Blood Vol 109(3) (1061-1068)  DOI   2007
SOCS2 Can Enhance Interleukin-2 (IL-2) and IL-3 Signalling by Accelerating SOCS3 Degradation Molecular and Cellular Biology Vol 25(20) (9115-9126)  DOI   2005
SOCS3 regulates onset and maintenance of TH2- mediated allergic responses Nature Medicine Vol 9(8) (1047-1054)  DOI   2003
A Role of Suppressor of Cytokine Signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated Interleukin 2 Production J Exp Med Vol 17 (425-436)  2003
Matching SOCS with function Nature Immunology Vol 4(16) (507-509)  2003
Tyrosine phosphorylated SOCS-3 inhibits STAT activation but binds p120-RasGAP and activates Ras Nature Cell Biology Vol 3(5) (460-465)  DOI   2001