PRIME Study

The Lanyon Building
The Lanyon Building

What is the PRIME Study?

A Longitudinal Investigation of Periodontal Disease as a Risk Factor for Coronary Heart Disease and Stroke in the PRIME STUDY

The PRIME study was set up in 1991 to examine factors which are associated with heart disease and other cardiovascular disease such as stroke.

This study is investigating the relationship between periodontal disease and cardiovascular disease in men in Northern Ireland. Periodontal disease is what is commonly referred to as gum disease and causes damage to the bone supporting the teeth and ultimately may lead to the loss of some or all the teeth. We will also study whether the specific bacteria in dental plaque are associated with heart disease or stroke.

PRIME is a unique study and has improved our understanding of the reasons why some men get disease and some do not.