Institute of Agri-Food & Land Use

Lecturer in Biomolecular Targets

Postal Address:
Institute of Agri-Food & Land Use
Queen's University Belfast
David Keir Building
Stranmillis Road
Belfast BT9 5AG

Room:  01.330
Telephone:  +44 (0)28 9097 6535
Fax:  +44 (0)28 9097 6513
Email:  katrina.campbell@qub.ac.uk

Qualifications

• BSc (Hons) Biochemistry, 1995; Queen's University Belfast
• MMedSc in Ultrastructural Anatomy and Pathology, 1996; Queen's University Belfast
• PhD: Pharmacy, 2001; Queen's University Belfast
• PGCHET, 2007; Queen's University Belfast

Research Profile

Katrina obtained her BSc (Hons) in Biochemistry in 1995 and her MMedSc in Ultrastructural Anatomy and Pathology in 1996 from Queen's University Belfast.  Following a year working at Randox Laboratories in the development of clinical diagnostic test kits she returned to the Pharmacy department at Queen's University where she completed her PhD on Transdermal Drug Delivery in 2001.  From 2000 to 2006 she was employed as a post-doctoral research fellow for Queen's University based at the Veterinary Sciences Division in Stormont.  In 2006 she re-located to the Institute of Agri-Food and Land Use.  From 2000 she was/is highly involved in various research projects including:

• EU 5th Framework Project - Glucocorticoids
• Safefood Project - Coccidiostats in Poultry
• EU 6th Framework Project - BioCop: New Technologies to Screen Multiple Chemical Contaminants in Foods (http://www.biocop.org)
• EU 7th Framework Project - Conffidence: Contaminants in Food and Feed Inexpensive Detection for Control of Exposure (http://www.conffidence.eu)
• EU 7th Framework Project - Midtal: Microarrays for the detection of toxic algae (http://www.midtal.com/)
• EU 7th Framework Project - Microaqua: Innovative Aquatic biosensors (http://microaqua.eu/)
• Interreg Project - Atlantox: advanced tests about new toxins appeared in the Atlantic area
  (http://www.atlantox.com/)
• Interreg Project - Pharmatlantic: Knowledge Transfer Network for Prevention of Mental Diseases and Cancer in the Atlantic Area (http://www.pharmatlantic.org/
• NSF funded Project - Beacons: Biosafety for environmental contaminants using novel sensors.
• Collaborative Research Project - Flippers; Field & Laboratory Immunogical Phycotoxin Poison Examination by Rapid Sensors

Katrina has been actively engaged in research for 12 years mainly involved on working on multi-centre research projects aimed at developing innovative screening methods for the detection of chemical contaminants and toxins in food and feeds.  She has developed a variety of multidisciplinary research skills and gained extensive experience in method development, validation, evaluation, end product formation and technology transfer workshops and events for dissemination.

Professional Bodies

• Member of Royal Society of Chemistry
• Member of Society of Biology
• Member of the Ulster Immunology Group
• Fellow of the Higher Education Academy (FHEA)

Refereed Publications

Betsy Jean Yakes, Samantha Prezioso, Simon A. Haughey, Katrina Campbell, Christopher T. Elliott and Stacey L. DeGrasse (2011). An Improved Immunoassay for Detection of Saxitoxin by Surface Plasmon Resonance Biosensors.  Sensors and Actuators B, 156: 805-811.

Hester van den Top, Simon Haughey, Natalia Vilariño, Luis Botana, Hans van Egmond, Chris T. Elliott, Katrina Campbell (2011). Surface Plasmon Resonance Biosensor Screening Method for Paralytic Shellfish Poisoning Toxins: A Pilot Interlaboratory Study.  Analytical Chemistry, 82: 2977-2988.

Raymond Devlin, Katrina Campbell, Kentaro Kawatsu, Christopher T. Elliott (2011). Physical and immunoaffinity extraction of paralytic shellfish poisoning toxins from cultures of the dinoflagellate Alexandrium tamarense.  Harmful Algae, 10(5): 542-548.

Raymond Devlin, Katrina Campbell, Kentaro Kawatsu, Christopher T. Elliott (2011). Studies in the use of magnetic microspheres for immunoaffinity extraction of paralytic shellfish poisoning toxins from shellfish.  Toxins, 3: 1-16.

Katrina Campbell, Terry McGrath, Stefan Sjölander, Thord Hanson, Mattias Tidare, Östen Jansson, Anna Moberg, Mark Mooney, Christopher Elliott, Jos Buijs (2011). Use of a novel micro-fluidic device to create arrays for multiplex analysis of large and small molecular weight compounds by surface plasmon resonance.  Biosensors and Bioelectronics, 26, 3029-3036.

Katrina Campbell, Dorothea F.K. Rawn, Barbara Niedzwiadek and Christopher T. Elliott (2011). Paralytic shellfish poisoning (PSP) toxin binders for SPR analysis: problems & possibilities for the future, a review.  Food Additives and Contaminants Part A, 28(6): 711-725.

Katrina Campbell, Natalia Vilariño, Luis M. Botana, Christopher Elliott (2011). A European perspective on progress in moving away from the mouse bioassay for marine toxin analysis.  Trends in Analytical Chemistry, 30(2): 239-253.

Luis M. Botana, Natalia Vilariño, Amparo Alfonso, Carmen Vale, Carmen Louzao, Christopher T. Elliott, Katrina Campbell, Ana M. Botana (2010). The problem of toxicity equivalent factors in developing alternative methods to animal bioassays for marine-toxin detection.  Trends in Analytical Chemistry, 29(11): 1316-1325.

Michel Dubois, Luc Demoulin, Caroline Charlier, Philippe Delahaut, Katrina Campbell, Chris Elliott, Samuel Godefroy, Gurmit Singh (2010). Development of ELISAs for detecting domoic acid, okadaic acid, and saxitoxin and their applicability for the detection of marine toxins in samples collected in Belgium.  Food Additives & Contaminants, 27(6): 859-868.

Katrina Campbell, Simon A. Haughey, Hester van den Top, Hans van Egmond, Natalia Vilariño, Luis M. Botana, Christopher T. Elliott (2010). Single Laboratory Validation of a Surface Plasmon Resonance Biosensor Screening method for Paralytic Shellfish Poisoning Toxins.  Analytical Chemistry, 82: 2977-2988.

Katrina Campbell, Anne-Catherine Huet, Caroline Charlier, Cowan Higgins, Philippe Delahaut and Christopher T. Elliott (2009). Comparison of ELISA and SPR biosensor technology for the detection of paralytic shellfish poisoning toxins.  Journal of Chromatography B., 877(32): 2009, 4079-4089.

Dorothea F.K. Rawn, Barbara Niedzwiadek, Katrina Campbell, H. Cowan Higgins and Christopher T. Elliott (2009). Evaluation of surface plasmon resonance relative to high pressure liquid chromatography for the determination of paralytic shellfish toxins.  Journal of Agricultural and Food Chemistry, 57(21): 10073-10080.

G.R. Marchesini, H. Hooijerink, W. Haasnoot, M.W.F. Nielen, J. Buijs, K. Campbell, C.T. Elliott and M.W.F. Nielen (2009). Towards Surface Plasmon Resonance biosensing combined with bioaffinity-assisted nano HILIC Liquid Chromatography / Time-of-flight Mass Spectrometry identification of Paralytic Shellfish Poisons.  Trends in Analytical Chemistry, 28(6): 792-803.

Michael O'Keeffe, Katrina Campbell, Martin Danaher, Emiliana Capurro, Glenn Kennedy, Christopher T. Elliott (2008). Survey of dinitrocarbanilide residues in poultry products.  Food Additives and Contaminants, 25(1).

Eva S. Fonfría, Natalia Vilariño, Katrina Campbell, Chris Elliott, Simon A. Haughey, Kentaro Kawatsu and Luis M. Botana (2007). Paralytic shellfish poisoning detection by SPR-based biosensors in shellfish matrixes.  Analytical Chemistry, 79(16).

Katrina Campbell, Linda D. Stewart, Terence L. Fodey, Simon A. Haughey, Gregory J. Doucette, Kentaro Kawatsu and Christopher T. Elliott (2007). An assessment of specific binding proteins suitable for the detection of paralytic shellfish poisons (PSP) using optical biosensor technology.  Analytical Chemistry, 79(15): 5906-5914.

Michael O'Keeffe, Emiliana Capurro, Martin Danaher, Katrina Campbell and Christopher T. Elliott (2007). Investigation of the causes for occurrence of residues of the anticoccidial feed additive nicarbazin in commercial poultry.  Food Additives and Contaminants, 24(9): 923-934.

Katrina Campbell, Terence Fodey, Jonathan Flint, Christopher Danks, Martin Danaher, Michael O'Keeffe, D. Glenn Kennedy and Christopher Elliott (2007). Development and validation of a lateral flow device for the detection of nicarbazin contamination in poultry feeds.  Journal of Agricultural and Food Chemistry, 55(6): 2497-2503.

O. Van den Hauwe, K. Campbell, S.R. Crooks, R. Schilt, C.H. Van Peteghem (2005). Confirmation of synthetic glucocorticoids with liquid chromatography/mass spectrometry: organization and results of an international interlaboratory comparison test.  Journal of AOAC International, 88(1).

Woolfson, A.D., Malcolm, R.K., Campbell, K., Jones, D.S. and Russell, J.A. (2000). Rheological, mechanical and membrane penetration properties of novel dual drug systems for percutaneous delivery.  Journal of Controlled Release, 67 (2-3).

Russell, J.A., Malcolm, R.K., Campbell, K., Woolfson, A.D. (2000). High-performance-liquid-chromatography determination of 17 beta-estradiol and 17 beta-estradiol-3-acetate solubilities and diffusion coefficients in silicone elastomeric intravaginal rings.  Journal of Chromatography B. Biomedical Sciences and Applications, 744 (1).