Dr. G.P. Brennan
Dr. Gerry Brennan
BSc. Biological Sciences, 1979,
University of Ulster;
PhD. Electron microscopy methodologies and
their application in a study of flatworm parasites
and other biological tissues, 1993,
Queen's University Belfast.
Tel: +44 (0)28 9097 2083 (Direct line)
Fax: +44 (0)28 9097 5877
Room: Medical Biology Centre - 0G.433
Co-ordinate School seminar programme Module coordinator.
Parasitology: electron microscopy: neurobiology. The research can be classified in to four principal areas: (i) ultrastructural studies of worm form and function (ii) the action and metabolism of anthelmintics (iii) identification and localization of neurotransmitters (iv) molecular studies to localize genes at the ultrastructural level.
Some ongoing research projects:
Nerve-muscle organisation of the feeding apparatus of the potato cyst nematode Globodera pallida: The control of egg release in the pig gastrointestinal parasite, Ascaris suum. Ultrastructural and immunological analysis of the gastrointestinal tract of the sheep scab mite, Psoroptes ovis.
Studies on anthelmintics:
To determine the efficacy of selected anthelmintics against resistant Fasciola hepatica in sheep; Studies on the mode of action of the anthelmintic Triclabendazole against Fasciola hepatica; Activity of flukicidal drugs: from target parasite to non-target species in the environment.
Immunocytochemistry and neurotransmitters:
A number of research projects are focussed on the ultrastructural localization and identification of the sensory neuroanatomy of parasites of economic and veterinary importance, these include, the trematodes Fasciola hepatica and Schistosoma mansoni, the nematodes Ascaris suum, Trichostrongylus columbriformis, Teladorsagia circumcincta and Haemonchus cortortus, and the potato cyst nematode Globodera pallida.
Control of mites of veterinary importance. The chicken mite Dermanyssus gallinae and the sheep scab mite Psoroptes ovis - molecular and ultrastructural characterization of novel endectocide targets will be identified using molecular biological techniques and localised using in situ hybridisation.
British Council Link Coordinator India Council Member and Honorary Treasurer for the Microscopical Society of Ireland Collaborative research links with: Madras University (fish parasites; prawn aquaculture) Dublin City University (parasite immunocytochemistry) Veterinary Research Division Storomont (sheep anthelmintics) Moredun Institute (nematode immunocytochemistry) Central Science laboratory, York (mite studies) Merial - veterinary pharmaceutical company (efficacy of anthelmintics) University of Malaysia (fish monogeneans).