Basic and clinical research to improve the prevention, detection and treatment of infection.
a. Respiratory Infectious Diseases
Research activities are focused on the use of (i) enhanced culture techniques, including culture of anaerobic bacteria and (ii) non culture methods based methods (next- generation sequencing, sensor technology) to improve the detection and treatment of lung infection in patients with respiratory diseases such as cystic fibrosis (CF), bronchiectasis and COPD.
b. Antimicrobial stewardship
Research activities are focused on clinical and laboratory based studies to ensure effective use of antimicrobials to reduce the emergence of antimicrobial resistance.
c. Novel antimicrobials and anti-infective biomaterials
Research activities are focused on the (i) development of efficient methods to prevent or eradicate bacterial biofilm infection and (ii) discovery of new antibiotics and antibiotic adjuvants capable of either destroying biofilms or increasing their sensitivity to conventional antibiotics.