Find a PhD supervisor

Centre for Cancer research and Cell Biology

Research Opportunities

Supervisors

  • Gynaecological Cancer

  • Surgical Gynaecological research

Dr James Beirne
  • Technology/platform-agnostic prior knowledge transfer 

  • Compositional statistics

  • Pre-clinical model selection/chacterisation

  • Prognostic/predictive subtyping

  • Consensus/meta-clustering

  • Landmark analysis

  • Progression routes from pre-malignancy to cancer

  • Mixed signal deconvolution/convolution 

Dr Jaine Blayney
  • Mechanisms of radioresistance

  • Drug radiotherapy combinations

  • In vivo models and small animal radiotherapy

  • Nanoparticle theranostics

Dr Karl Butterworth
  • Radiobiology of targeted radionuclides (Radium-223)
  • Clinical trials
  • Stereotactic Radiotherapy
  • Radiation Biology
  • Prostate Cancer
Dr Aidan Cole
  • Cancer clinical trials
  • Basic scientific and translational investigation of mechanisms of treatment resistance
Dr Vicky Coyle
  • Investigate molecular mechanisms involved in dysregulation of the ubiquitin proteasome system in multiple myeloma
  • Identify opportunities for therapeutic intervention
Dr Lisa Crawford
  • Receptor signalling

  • Membrane trafficking

  • Inter-organelle interactions

Dr Emma Evergren
  • Developing clinical biomarker strategies in cancer

  • Using comprehensive genomic approaches to detect DNA alterations

Professor David Gonzalez de Castro
  • Clinical and Scientific PhD and MD Fellowships in breast and lung cancer, with an emphasis on treatment with radiotherapy

Dr Gerry Hanna
  • DNA damage repair
  • Transcriptional regulation
  • Mechanisms of sensitivity/resistance to DNA damage based therapeutics
Professor Paul Harkin
  • Identifying novel predictive and prognostic biomarkers for radiotherapy treatment in prostate cancer

Dr Suneil Jain
  • Digital molecular pathology approaches to characterize the immune contexture of cancers using high quality biosamples
  • Investigating the role of the oral microbiome in cancer risk and malignant transformation
  • Identifying and validating molecular biomarkers for stratification of patients with cancers
Dr Jacqueline James
  • Characterisation of a molecular group in solid cancers that represents an innate immune response to DNA damage through the STING pathway

  • Development of a gene expression based biomarker panel that can identify pathways related to the hallmarks of cancer and guide patient therapy

Professor Richard Kennedy
  • Investigate key processes involved in the underlying biology driving epigenetic alterations

  • Nucleotide metabolism in cancer development 

  • Novel drug targeting of these processes through in vitro cell line-based models and in vivo cancer mouse models

Dr Melissa LaBonte Wilson
  • Cancer biology
  • Cell death
  • Drug resistance
Professor Daniel Longley
  • Integrative analytics & software design 

  • Insights into patient heterogeneity 

  • AI and Machine Learning

Dr Daragh McArt
  • Characterisation of a molecular group in solid cancers that represents an innate immune response to DNA damage through the STING pathway
  • Development of a gene expression based biomarker panel that can identify pathways related to the hallmarks of cancer and guide patient therapy
Dr Nuala McCabe
  • Benign or malignant urology

  • Ion channels in health and disease

Dr Karen McCloskey
  • Transcription dysfunction in disease

  • Functional genomics and integrative bioinformatics

  • Identification of novel genomically informed treatment strategies

Dr Simon McDade
  • Improved understanding of tumour initiating events in BRCA mutation carriers

  • Investigation and management of breast cancer risk

  • Development of treatment biomarkers in the pre-surgical setting

Dr Stuart McIntosh
  • Modelling responses to radiotherapy, including;

  • Proton Relative Biological Effectiveness

  • Intrinsic radiosensitivity

  • The impacts of intercellular communication on radiation responses

Dr Stephen McMahon
  Professor Ian Mills
  • Investigations into molecular mechanisms in myeloid blood cancers including epigenetic alterations

  • DNA repair deficiency

  • Altered signal pathways to identify therapeutic targets for novel agents or repurposed drugs using drug screens and/or NGS technologies to improve patient outcomes

Professor Ken Mills
  •  Transcriptional control

  • Signal transduction

  • Chromatin remodeling and epigenetics

  • DNA damage signalling

  • Cell Senescence

  • Molecular cell biology

  • Biochemistry

Dr Paul Mullan
  •  Cancer predisposition genetics

  • Molecular pathology

  • Functional genetics

Dr Nick Orr
  • Bone-seeking radionuclides in prostate cancer

  • New therapeutics in CRPC

  • Advanced radiotherapy in prostate cancer

  • Genomic stratification in prostate cancer

Professor Joe O'Sullivan
  • Systems Medicine, Network Biology, Precision Medicine; with applications to cancer biomedicine.

  • Funded PhD studentship 2019-2022, project title: “Precision Diagnostics For Novel Cancer Patient Journey-wide Phenotypes”

Dr Ian Overton
  •  STING pathway across cancers
Dr Eileen Parkes
  • Optimization of bone-seeking radionuclides for targeted molecular radiotherapy

  • Defining stem-cell mediated radioresistance in recurrent brain tumours

  • Building a biological-based rationale for the use of particle-based radiotherapies

  • Understanding Radiation-induced bystander and abscopal responses

  • Defining Next generation laser-produced ion-beams for advanced radiotherapy

Professor Kevin Prise
  • Cellular DNA damage response system and its link with cancer development

Dr Kienan Savage

 

Professor Manuel Salto-Tellez
  • Nanomedicine

  • Antibody therapeutics

  • Proteases and pancreatic cancer

Professor Christopher Scott
  • Chromatin remodelers

  • Epigenetics

  • Cancer metastasis

  • Proteomics

  • Molecular cell biology

  • Biochemistry

Dr Adone Tielenius Kruythoff-Modh Sarip
  • Laboratory based investigation of novel drugs and biomarkers

  • Discovery of resistance mechanisms to therapy

  • Innovative biomarker development using clinical samples

Dr Richard Turkington
  • Laboratory based investigations into molecular mechanisms including altered pro-survival signaling pathways in RASMT and BRAFMT CRC

  • Discovery of novel resistance mechanisms to therapy mechanisms in RASMT and BRAFMT CRC

  • Innovative biomarker development using samples from RASMT and BRAFMT CRC patients

Dr Sandra Van Schaeybroeck
  • Development of Novel Cathepsin V inhibitors to Validate role in Breast Cancer

  • Testing of Epigenetic Probes in Cancer Immune Cells

  • Design, synthesis and SAR exploration of Novel LSD1 inhibitors

Dr Richard Williams

Centre for Public Health

 

Research Opportunities

Supervisors

  • Cancer epidemiology

  • Autoimmune conditions in particular pernicious anaemia

Dr Lesley Anderson
  • Primary and secondary research on visual disorders

Professor Augusto Azuara-Blanco
  • Novel methodological approaches for cancer survival analysis

Dr Finian Bannon
  • Use of systems approaches

  • Analytics/intelligence and modelling to improve the quality and safety of health and social care

Dr Declan Bradley
  • Epidemiology

  • Pharmacoepidemiology

Dr Christopher Cardwell
  • Improving the quality and usefulness of trials and reviews

  • Conducting health services research more generally

  • Conducting research relevant to humanitarian emergencies

Professor Mike Clarke
  • Data analysis

  • Epidemiology projects related to oesophageal or colorectal cancer and pre-malignant conditions

Dr Helen Coleman
  • Strategies to correct and prevent myopia among children in low-resources areas of LMICs

  • Measuring early outcomes in cataract surgery in underserved areas

  • Improved care for complex diseases such as glaucoma and diabetic eye disease in rural Asia

Professor Nathan Congdon
  • Mental Health

  • Ageing

  • Co-morbidity/Multi-morbidity

  • Social determinants of health/social environment

  • Subjective well-being

Dr Sharon Cruise
  • Development and evaluation of health services and public health interventions

  • Implementation science and improvement science

  • Integrated health and social services

  • Service organization and delivery

Professor Michael Donnelly
  • Patient reported outcomes data on 35,000 prostate cancer patients from the UK

  • Excellent data of all cancer patients diagnosed since 1993

  • Databases on premalignant disease and PSA database

  • Stroke registry to be established

  • Possible cardiovascular in future

Dr Anna Gavin
  • Ophthalmic epidemiology

  • Optometry

  • Vision science

  • Psychophysics

  • Ophthalmology

Dr Ruth Hogg
  • The role of social networks and network interventions for behavior change

  • Developing and investigating the public health impact of population level built and social environment interventions

Dr Ruth Hunter
  • Opportunities in life-course epidemiology and methods, complex public health interventions and decision sciences

Professor Frank Kee

  • Blindness prevention

  • Pediatric palliative care

Dr Lynne Lofield
  • Social science or clinical background
Dr Aideen Maguire
  • Large scale genomics of chronic kidney disease including genome-wide and epigenetic association studies

  • Clinical epidemiology of chronic kidney disease

  • Decision making and conservative management of end-stage renal disease

  • Medical education projects with focus on intravenous fluid therapy

Professor Peter Maxwell
  • Epidemiology

  • Rare disease, research methodology, health service research and network analysis. 

Dr Helen McAneney
  • Development and implementation of psychological interventions for people with neurodegenerative illness

  • Implementation of quality improvement programs in palliative care

  • Development and implementation of healthcare quality inspection techniques

  • Development and implementation of evidence-based interventions for reduction of loneliness among older people

Dr Noleen McCorry
  • Nutrition and ageing research

  • Data analysis in cohort studies and clinical/community - based dietary interventions 

Dr Claire McEvoy

 

  • Behaviour change interventions focusing on diet and/or obesity across a range of population groups
  • Obesity management
  • Preconception health for men and women - improving health status before pregnancy
Dr Laura McGowan
  • Dementia research including the role of nutrition and inflammation in neurodegeneration

  • The utility of EEG and MEG in assisting diagnostics

  • Large data analytics projects

Dr Bernadette McGuinness
  • Diabetic complications
  • Biomarker discovery
  • Stratified Medicine
Dr Gareth McKay
  • Improving oral health for care home residents

  • Exploring links between oral health and nutritional well being

  • Improving care for head and neck oncology patients

Dr Gerry McKenna
  • Nutrition and prevention/management of obesity

  • Diabetes and cardiovascular disease

Dr Michelle McKinley
  • Genetic-epigenetic-transcriptomic association studies for kidney disease.

  • Multi-omic risk factors for rare disease, and common diseases with a focus in aging populations. 

  • Information and communication provision for kidney disease and rare disease(s).

Dr Amy Jayne McKnight
  • Discrete choice models
  • Secondary data analysis
  • Longitudinal data
Dr Vikki O'Neill
  • Research on administrative data related to ageing, pensions, poverty at older ages
  • Research on looked after children or children known to social services.
Dr Dermot O'Reilly
  • Translational Research 

  • Risk Factors and Biomarkers in the various dementia syndromes

Dr Peter Passmore
  • Ophthalmic image analysis

  • Diabetic retinopathy screening

  • Epidemiology of eye diseases in different populations around the world

Professor Tunde Peto
  • Physical Activity
  • Sedentary behaviour and exercise in school, workplaces or with older adults
Dr Mark Tully
  • Nutrition, particularly dietary intervention studies

  • Projects involving innovative dietary assessment and behaviour change interventions

Professor Jayne Woodside

 

Centre for Experimental Medicine

 

Research Opportunities

Supervisors

  • Critical care studies that include studies conducted within and after ICU; ICU survivorship; trial methodology studies

Professor Bronagh Blackwood
  • Airway Clearance

  • Exercise and rehabilitation

  • Methods for optimizing clinical trials

Professor Judy Bradley
  • Signal transduction

  • Molecular cell biology

  • Mouse models of disease and drug discovery targeting Grem1 and other proteins involved in human disease

Dr Derek Brazil
  • Epithelial biology 

  • Immunology

  • Microbiology

Dr Eric Campbell
  • Innate immunity

  • Cell and molecular biology

  • Retinal pathophysiology

Dr Mei Chen
  • Microvascular biology and disease

  • Pharmacological

  • Gene therapy-based approaches

Professor Tim Curtis
  • To study the role of the histamine four receptor in the regulation of neutrophil phagocytosis 

  • To study the role of acidic pH in the regulation of anti-microbial functions of neutrophils

Dr Karim Dib

 

Dr Yvonne Dombrowski
  • Cystic fibrosis
  • Bronchiectasis
  • Pneumonia

Dr Damian Downey

  • Harnessing inflammation for repair and regeneration in dental tissues
  • neuronal-immune cells signalling in inflammatory and neuropathic pain
  • Investigate potential links between oral bacteria, systemic inflammation and cardiovascular disease
Dr Ikhlas El Karim
  • Immunology
  • Neuroscience
  • Stem/Progenitor cell biology
  • Tissue regeneration
  • Neuroinflammation
  • Demyelinating diseases
Dr Denise Fitzgerald
  • Cardiovascular biology

  • Pathophysiology

  • Pharmacology

Dr David Grieve
  • Non-adherence in asthma
  • Stratified Medicine / Personalised medicine
  • Health informatics / Health economics

Professor Liam Heaney 

  • Host-pathogen interactions
  • vaccinology
  • pharmacology
Dr Beckie Ingram
  • Investigation of the role of MSC exosomal miRNAs in epithelial and endothelial repair in ARDS

  • The role of MSC mitochondrial transfer in lung regeneration

  • The role of apoptosis in MSC therapeutic effects in ARDS 

 

Dr Anna Krasnodembskaya

  • Multidisciplinary environment to combine molecular, morphological and clinical approaches.

Dr Imre Lengyel
  • Biomedical informatics (translational bioinformatics and exposome informatics)

  • Integration of clinical and molecular data

  • Analysis and representation of exposome data

Dr Guillermo Lopez Campos
  • Various aspects of infection, pain and inflammation in the oral cavity and upper respiratory tract

Dr Fionnuala Lundy
  Dr Andriana Margariti
  • Cardiovascular medicine
  • Ophthalmology
  • Regenerative medicine

 Dr Denise McDonald

  • Neuroinflammation and airways disease
  • Early life influences on adult respiratory health
  • Cohort studies in Early COPD
  • Phase II/III Clinical trials in cough, asthma and COPD
Professor Lorcan McGarvey
  • Improving the diagnosis of serious infection in hospitalised patients
Dr Ronan McMullan
  • Vascular stem cell biology
  • Diabetic retinopathy
  • Diabetic vascular complications
  • Cellular senescence
  • Angiogenesis

 Dr Reinhold Medina

  • Molecular, cellular, genetic and disease models of inflammation and inflammatory diseases 

  • Identifying novel diagnostics and new therapeutic strategies in the treatment of inflammatory diseases. 

Professor Paul Moynagh
  •  

    Cellular microbiology of bacterial respiratory pathogens

     

     

  • Functional genomics of bacterial virulence factors
  • Subversion of innate immune cells by infection

  • Proteomics approaches to study signaling at the pathogen-host interface

     

Dr Gunnar Neels Schroeder
  • Respiratory syncytial virus biology, pathogenesis, and vaccines.
  • Paramyxovirus vaccine vectors, in particular Sendai virus.
  • Culture and exploitation of well-differentiated primary human airway epithelium cell cultures.

 Dr Ultan Power

  • Epithelial biology
  • Pathophysiology
  • Biomarkers of diseases

  • Bioinformatics

Dr Bettina Schock
  • Lung microbiome
  • Aerosol therapy in critical care
  • Prevention of post-operative pulmonary complications
  • Mechanistic studies to understand pulmonary inflammation and injury

Dr Murali Shyamsundary

 
  • MicroRNAs – their role in gene regulation and use as biomarkers
  • Transcriptomics – RNA-Seq, including single cell analysis
  • Microbial DNA sequencing
Dr David Simpson
  • Harnessing ECFCs to repair choriocapillaris during geographic atrophy
  • The role of the placental growth factor pathway in age-related retinal disease
  • Metabolic plasticity of retinal cells in ischaemia and the potential to regulate physiological angiogenesis
  • Identifying key molecular mechanisms underpinning ECFC dysfunction in diabetic microvascular disease.
  • Development of vascular stem cell therapy for ischaemic retinopathy
  • Combinatorial cell therapy for reversing tissue ischaemia
  • The potential of iPS cell technology to understand mechanisms underpinning patient responsiveness to anti-VEGF agents for diabetic macular oedema

 Professor Alan Stitt

  • Dysregulated protease activity in acute and chronic lung disease

Professor Cliff Taggart
  •  Molecular mechanisms of intrinsic multi-drug antibiotic resistance
  • Biogenesis of the Gram-negative bacterial outer membrane, especially lipopolysaccharide and cell wall peptidoglycan
  • Cellular microbiology of opportunistic  Gram-negative bacterial pathogens in phagocytic cells.
Professor Miguel A. Valvano
  • Heart failure, Cardiomyopathy, Cardiac remodelling
  • Diabetes, Hypertension, Ischaemia
  • Biomarkers, Epigenetics, Fibrosis
  • Global Health, mHealth

 Dr Chris Watson

  • Innate immunity

  • Repair and regeneration

  • MiRNA function

  • Transcriptomics in the field of acute and chronic lung inflammation and disease

Dr Sinéad Weldon
  • Immunology
  • Cell and molecular biology
  • Retinal pathophsyiology

  • Pharmacology

     

Professor Heping Xu

Centre for Medical Education

 

Research Opportunities

Supervisors

 

Professor Tim Dornan

  • Simulation based education

  • Medical Education

  • OSCEs

Professor Gerry Gormley
  • Medical education in the General Practice setting

  • Transformative learning

  • Safe care and quality improvement in healthcare

  • Novel platforms for medical education

Dr Nigel Hart

  • Medical education, using qualitative methodologies

Dr Jenny Johnston

  • Haematology

Professor Mary Frances McMullin