BSc|Undergraduate
Biochemistry with Professional Studies
Entry year
Academic Year 2023/24
Academic Year 2023/24
Entry requirements
BBB/ABB
BBB/ABB
Duration
4 years (Full Time)
4 years (Full Time)
UCAS code
C704
C704
Placement Year
Yes
Yes
Biochemistry is the molecular basis of life. It applies chemical principles to some of the most exciting problems in the life sciences industry. Biochemistry explains how drugs work, helps us understand what goes wrong in diseases, and enables ‘genetic engineering‘. Consequently, the subject is essential to drug discovery, biotechnology and biomedical research.
Biochemists investigate the structures, functions and biological roles of molecules involved in metabolism, cell signalling and the transmission of genetic information.
The BSc in Biochemistry with Professional Studies enables students to gain an understanding of the concepts and theories relating to Biochemistry and the application of a range of practical laboratory skills. Students will explore the relevant analytical principles and techniques, and apply these in a research setting. You will understand collation, quantitative analysis and interpretation of experimental data, and the ability to problem solve. Additional skills such as; personal and team skills, data management, presentation skills, career management planning and applying your degree in the workplace will also be covered.
Biochemistry with Professional Studies Degree highlights
Professional Accreditations
- Royal Society Accreditation
This course has been accredited by the Royal Society of Biology. Ultimately this award highlights the academic quality of the course and its contribution in ensuring that its graduates meet employer needs by acquiring the necessary skill set of both technical and transferable skills.
Industry Links
- Work placements on these programmes provide students with the opportunity to utilise the practical skills gained during the teaching of their degree and apply these in a work environment. Past students have gained work placement within organisations such as Almac, Warner Chilcott, Randox, Norbrook Laboratories, Altnagelvin Hospital and Belfast City Hospital.
Student Experience
- Final year research projects allow students to gain considerable research experience in one of the research laboratories at Queen’s University Belfast. Working alongside world-leading researchers enriches the students experience and assists them in pursuing a career in biochemical research.
Studying biochemistry at Queen’s really made my passion for the sciences come alive and gave me the confidence and necessary skills to branch out into the next stage of my life. If you are prepared to stay dedicated and work hard, the possibilities are endless. (Laura Witherow, BSc Biochemistry 2015)
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Course content
Course Structure
| Introduction | The Biochemistry degree at Queen’s University Belfast, investigates the structures, functions and biological roles of molecules involved in metabolism, cell signalling and the transmission of genetic information. Research-led teaching and the opportunity to complete an integrated Master programme, help prepare our students for a career in biochemical research. Throughout Stages 1 and 2, practical classes in Biochemistry reinforce and complement the theory, providing students with a solid foundation on which to build upon for Stage 3. At the end of Stage 2, BSc Students may be eligible to transfer to the same named MSci degree pathway provided they meet certain requirements. MSci students may also transfer to the BSc degree at any point in stages 1 and 2. BSc Biochemistry with Professional Studies students may be eligible to transfer to the same named MSci degree pathways provided they meet certain requirements |
|---|---|
| Year Out | Biochemistry with Professional Studies students undertake a one year, degree-related work placement (year out) between Stages 2 and 3. |
People teaching you
Contact Teaching Times
| Large Group Teaching | 12 (hours maximum) Typically around 9 hours teaching [3 hours for each subject/module studied – see later information on course content] and 3 hours practical each week. |
|---|---|
| Personal Study | 28 (hours maximum) For private study and writing assignments each week |
Learning and Teaching
We provide a range of learning experiences on the BSc Biochemistry with Professional Studies programme, to enable students to engage with subject experts and develop attributes and perspectives that will equip you for life and work.
- Innovative Technologies and a World Class Library
Students can make use of innovative technologies and a world class library that enhances their development as independent, lifelong learners. Examples of the opportunities provided for learning on this course are: E-Learning technologies, lectures, personal tutor, practical classes, research projects, self-directed study and work placement.
Assessment
Details of assessments associated with this course are outlined below:
- The way in which you are assessed will vary according to the Learning objectives of each module. Some modules are assessed solely through project work or written assignments. The majority are assessed through a combination of coursework and end of semester examinations. Details of how each module is assessed are shown in the Student Handbook which is provided to all students during their first year induction. This is also available online on our School website.
Feedback
As you progress through your course you will receive general and specific feedback about your work from a variety of sources including lecturers, module co-ordinators, placement supervisors, personal tutors, advisers of study and your peers. As a university student, you will be expected to take a greater role in reflecting on this and taking the initiative in continuously improving the quality of your work. Feedback may be provided to you in a variety of forms including: formal written comments, face to face comments, placement employer comments or references, online or emailed feedback, pre-submission advice, feedback and outcomes from practical classes, and others.
- Once you have reviewed your feedback, you are encouraged to identify and implement further improvements to quality of your work.
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Overview
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Modules
Modules
The information below is intended as an example only, featuring module details for the current year of study (2022/23). Modules are reviewed on an annual basis and may be subject to future changes – revised details will be published through Programme Specifications ahead of each academic year.
- Year 1
Core Modules
Molecular Basis of Life (40 credits)Molecular Basis of Life
Overview
Genetics and the Molecular Toolbox is a Stage 1 20 CAT module that runs in semester 2. The module provides a comprehensive introduction to the concepts of Genetics from fundamental to applied and builds on the knowledge gained through the pre-requisite module BIO1103 Molecular Basis of Life. Students will develop broad knowledge of genetics, genomics, and associated molecular tools and technologies. The course begins with an introduction classical genetics (chromosome structure, cytogenetics, diploid inheritance, allelic and epistatic interactions, aneuploidy, polyploidy, cytoplasmic inheritance) and population genetics to understand the importance of natural selection and evolutionary processes. This will be followed by the introduction to modern genetics tools and molecular techniques through a series of Toolbox sessions. Focus will be on ‘omics technologies including bioinformatics, and practical methods in molecular and cellular biology including genetic engineering tools and biochemistry techniques. The applications of genetic engineering, biotechnology, and tools/assays will be explored in the form of case studies. Students will also gain an understanding of the genetic/molecular basis of disease.
Learning Outcomes
On successful completion of this module students will be able to:
LO1: Demonstrate knowledge and understanding of the molecular basis of genetics (classical, population and evolutionary)
LO2: Demonstrate understanding of bioinformatics and how to use software to interrogate datasets
LO3: Describe recent advances in genetic, molecular, and biochemical tools including genetic manipulation and ‘omics’ technologies
LO4: Discuss the applications of genetics and genetic tools to biotechnology, medicine and scientific research
LO5: Develop problem solving skills and the ability to analyse data.
LO6: Demonstrate Good Laboratory Practice (GLP), and appropriate health and safety in the laboratory and ethical practices.
LO7: Demonstrate competence in specific laboratory practical and manipulative skills
LO8: Develop an awareness of steps required to translate basic scientific research into commercial and/ or practical applications.Skills
Development of laboratory skills related to molecular biology, biochemistry and genetics as evidenced through Practical Skills Portfolio; Group project work; Report writing; Critical and logical analysis of data; Peer and self-assessment; Computational analyses of genome/transcriptome data
Coursework
40%
Examination
60%
Practical
0%
Stage/Level
1
Credits
40
Module Code
BIO1304
Teaching Period
Full Year
Duration
24 weeks
The World of Microorganisms (40 credits)The World of Microorganisms
Overview
The World of Microorganisms (BIO1301) is a 20 CAT module that is underpinned by the semester 1 module ‘Fundamentals of Microbiology’. In this module students will explore: microbial interactions examining their role in food, health and the environment; study aspects of microbial pathogenicity in humans and animals and their impact on the immune system; and learn about some aspects of microbial biotechnology. Case studies will be used to relate learning to real-world context.
Learning Outcomes
On successful completion of this module students will be able to:
LO1: Describe and explain how microorganisms relate to production and use of food
LO2: Discuss aspects of biogeochemistry including marine microbiology’s role in maintaining a healthy Earth
LO3: Discuss microbial adaptations to extreme environments
LO4: Demonstrate the biotechnological potential of microorganisms for the benefit of humankind.
LO5: Discuss how microorganisms may contribute to the manifestation of disease and how this can be prevented
LO6: Demonstrate competence in microbiology specific laboratory practical and manipulative skills.
LO7: Develop problem solving skills.
LO8: Demonstrate the ability to work as part of a team.Skills
By the end of the module, students should have developed competence in practical laboratory skills related to microbiology, as well as reading, numerical, and scientific problem-solving skills. In addition to effective assimilation of knowledge they will gain experience of word processing, numerical procedures, interpretation of data, team working and problem solving.
Coursework
40%
Examination
60%
Practical
0%
Stage/Level
1
Credits
40
Module Code
BIO1301
Teaching Period
Full Year
Duration
24 weeks
Fundamentals of Chemistry (20 credits)Fundamentals of Chemistry
Overview
STAFF
NAME CONTRIBUTION
Dr A. C. Marr a.marr@qub.ac.uk
Module Co-ordinator
General Chemistry - 18 Lectures; Skills Workshops – part 1, Essential Calculations for Practical Chemistry
Dr P. C. Marr p.marr@qub.ac.uk
Skills workshop – Laboratory Skills parts 1 and 2
Prof. P. Stevenson p.stevenson@qub.ac.uk
Organic Chemistry: Functional Group Chemistry 15 Lectures, 5 Seminars Organic Chemistry Laboratory
Dr P. Dingwall p.dingwall@qub.ac.uk
Organic Chemistry Laboratory
Dr M. Swadzba-Kwasny Swadzba-kwasny@qub.ac.uk
Skills workshop – Scientific writing and researching skills.
Course content
General Chemistry - Elements, Atoms, ions, electrons and the periodic table. This course aims to give an introduction to the fundamental principles of atoms from the chemists’ viewpoint. Starting from a simple model and using the results of quantum mechanics a more appropriate model of the atom is presented. From this model trends in atomic and ionic properties which enable us to explain differences and similarities and predict the properties of different elements can be deduced. The following topics are covered:
* The Basics: Element, The periodic table, atom, mole.
* The Atom: The Bohr Atom.
* The Electron: Wave-Particle Duality and The Schrödinger Wave Equation, Probability Density, Radial Distribution Function, Orbitals, Quantum Numbers, s and p Orbitals, Phase, d Orbitals.
* More than One Electron: Filling orbitals, The aufbau principle, The Pauli Exclusion Principle, Hund’s rules, Penetration, Shielding, Effective Nuclear Charge, Slater’s Rules, Size.
* Trends: Ionization energy, Electron attachment enthalpy (affinity), Electronegativity, Ionic radii, Polarizability and polarizing power, Hydration enthalpies, Redox potentials. General Chemistry - Structure and Bonding. This course introduces some important theories of bonding. Theories of bonding are discussed in some detail for discrete molecules. The discussion of bonding in molecular species centres on the valence bond and molecular orbital theories. Intermolecular forces between molecules are also discussed.
* Introduction to bonding: Discussion of types of structure and common bonding theories, examples of representative structures.
* Homonuclear Diatomic Molecules: Interatomic distance and covalent radii, Potential energy curves, attractive and repulsive forces, bond energy and enthalpy. Lewis structures, filled shells, the octet rule. Wavefunction, introduction to valence bond theory and molecular orbital theory, Valence bond theory: ionic and covalent contributions, resonance; Molecular orbital theory: molecular orbitals, linear combinations of atomic orbitals, orbital overlap, bonding and antibonding orbitals, MO diagrams, some shapes of MO’s, labelling MO’s, examples of simple MO diagrams, bond order.
* Heteronuclear Diatomic Molecules: Lewis structures, valence bond approach, Molecular orbital theory, energy matching, symmetry, non-bonding orbitals; electronegativity, electric dipole moments, carbon monoxide, isoelectronic molecules.
* Polyatomic Molecules: Metal complexes and covalent polyatomics, coordination number, common geometries, molecules obeying the octet rule, valence bond theory, expanding the octet, hybridization (sp, sp2, sp3), formal charge, single, double and triple carbon-carbon bonds, molecular shapes; molecular orbital theory: ligand group orbitals; comparison of VB and MO, macromolecules, fullerenes, proteins and hydrogen bonding.
* Intermolecular Forces: Van-der-Waal forces, strength of forces.
* Introduction to solids with extended structures: metals and semi-metals, ionic solids and covalent solids. Only covered if time permits. ORGANIC CHEMISTRY: Functional Group Chemistry
* Draw structural formula to represent organic compounds, identify isomers and convert structural formula to molecular formula.
* Identify common organic functional groups, name organic compounds containing these groups, and predict their chemistry and reactivity.
* Recognise nucleophiles, electrophiles and bases and identify which chemistry these species participate in. Appreciate the importance of acidity and basicity in organic chemistry
* Sketch substitution, elimination and addition mechanisms and appreciate the importance of ‘mechanism’ in rationalising organic chemical reactions. * Suggest reagents for interconverting one functional group into another. * The functional groups which will be used to illuminate these outcomes are alkanes, alcohols, amines, alkyl halides, alkenes, alkynes, carbonyls compounds including aldehydes, ketones, carboxylic acids, esters and amides.
SKILLS WORKSHOPS:
* Scientific writing and researching skills
* Laboratory skills
* Essential calculations for practical chemistry
ORGANIC CHEMISTRY LABORATORY:
* 3 x 3 hours laboratories with associated write-ups.Learning Outcomes
Students will become familiar with chemical descriptions of matter. What matter is made up of, how it can be organised into the periodic table and how we can start to understand it from a scientific perspective. They will learn about organic compounds and how they can be prepared, named and reacted.
Skills
Learners are expected to demonstrate the following on completion of the module:
* Ability to write and predict atomic structure and properties.
* Ability to explain and understand bonding.
* Ability to recognise functional groups in organic chemistry and name compounds.
* Ability to suggest reagents, mechanisms and reactions in organic chemistry.
* Ability to demonstrate fundamental skills in laboratory practice and associated calculations.Coursework
50%
Examination
0%
Practical
50%
Stage/Level
1
Credits
20
Module Code
CHM1011
Teaching Period
Autumn
Duration
12 weeks
Structure, Reactivity and Mechanism in Organic and Bioorganic Chemistry
Overview
STAFF
NAME CONTRIBUTION
Dr. K.Tchabanenko
k.tchabanenko@qub.ac.uk STRUCTURE AND CHEMISTRY OF FUNCTIONAL GROUPS
(12 Lectures, 1 Seminar); INFRARED, ULTRAVIOLET AND VISIBLE SPECTROSCOPY (2 Lectures, 1 Seminar)
Dr. G. Sheldrake
g.sheldrake@qub.ac.uk AROMATIC CHEMISTRY (8 Lectures, 1 Seminars)
Dr. N. Gunaratne
N.Gunaratne@qub.ac.uk STEREOCHEMISTRY (5 Lectures, 1 Seminar)
Dr. S. Cochraine
s.cochrane@qub.ac.uk NATURAL PRODUCT CHEMISTRY (4 Lectures, 1 Seminar)
STRUCTURE AND CHEMISTRY OF FUNCTIONAL GROUPS
The concept of the functional group in organic chemistry. Review of the atom-to-atom bonding sequences, electron configuration, hybridization, geometry and electronegativity features of the common functional groups.
The following functional groups will be examined: halides, alcohols, cyanides, ethers, alkenes, alkynes, amines, aldehydes, ketones, acids, acyl halides, amides and esters. The emphasis will be on methods of introduction and interconversion and the important mechanistic links between them, viz. nucleophilic substitution, elimination, addition, reduction, oxidation, hydration and hydrolysis.
AROMATIC CHEMISTRY (8 Lectures, 1 Seminars)
Aromatic Chemistry of Benzene Derivatives
Bonding in benzene: Concepts of resonance, delocalisation and aromatic stabilisation.
Nomenclature of substituted aromatics.
SEar reactions: mechanisms and prominent (name) reactions: nitration, halogenation, acylation, and alkylation.
Distribution: mechanisms and direction (ortho, meta, para ratios).
Aromatic amines and diazonium salts: preparation and reactions of.
Phenols: preparation, acidity and reactions; preparation of aspirin.
Nucleophilic aromatic substitutions: various mechanisms and preparative applications.
Heterocyclic Chemistry
Classes: electron-deficient and electron-rich heteroaromatics.
Five-membered heterocycles: pyrrole, thiophene, furan (structure, properties, electrophilic substitution).
Six-membered heterocycles: pyridine (structure and substitution chemistry).
STEREOCHEMISTRY
Stereochemistry is described in this section of the module at an introductory level. Methods for drawing three-dimensional structures, including Fischer and Newman projections, and the notation used to indicate stereochemistry will be illustrated. Stereochemical descriptors for configuration and geometry (R and S; E and Z), and the sequence rules used for their assignment will be described.
We will define and distinguish the concepts of constitution, configuration, and conformation using clearly illustrated examples. The conformation, or three-dimensional shape of molecules, and the barriers to bond rotation, will be described and illustrated. A special focus will be placed on cyclohexane and the effects of ring substitution on the most stable conformation. We will then discuss different forms of stereoisomerism based on stereogenic tetrahedral carbon atoms, including enantiomers, diastereoisomers, and meso compounds, together with the difference between relative and absolute stereochemistry. Molecular chirality and the role of symmetry will be discussed, together with its occurrence in Nature.
Racemic mixtures, and resolution will be discussed in the context of optical activity and its measurement using plane polarised light.
Using these concepts we will develop an understanding of the stereochemistry of chemical reactions, which will be illustrated using examples of nucleophilic substitution and addition to carbon-carbon double bonds.
NATURAL PRODUCT CHEMISTRY
Carbohydrates: - classes, nomenclature and stereochemical conventions
- conformations, equilibria, mutarotation
- analytics and reactions of.
Amino Acids: - types and properties (ampoteric character, pl values,
analysis and detection)
- chemical reactions, synthesis, amide/peptide formation
- oligo- and polypeptides: natural occurance and molecular structures.
INFRARED, ULTRAVIOLET AND VISIBLE SPECTROSCOPY
The electromagnetic spectrum. Energy absorption.
IR Spectroscopy –
Hooke's Law approximation, stretching and bending vibration modes. IR spectrometers.
Characterisation by IR spectroscopy - group frequencies, finger print region. Specific group frequencies - C-H stretch, (bend), C=C and C=C stretch, O-H stretch, N-H stretch, C=O stretch (and factors affecting it), C=N stretch, o.m.p. bend in mono- and disubstituted benzene derivatives.
Uses of IR spectroscopy.
UV and Visible Spectroscopy.
Apparatus for uv/visible spectrometry.
Lambert-Beer Law.
Electronic excitation .
Chromophores. Effect of conjugation. Benzenoid compounds. Empirical rules for predicting wavelength of absorption of dienes and enones.Learning Outcomes
Upon completion of this module, the students will have gained a theoretical and practical understanding of basic Organic Chemistry. They will be able to relate organic chemistry to pharmaceutical and biological subjects.
Skills
Knowledge of basic organic chemistry. Practical experimental chemistry skills. Numeracy. Report writing.
Coursework
100%
Examination
0%
Practical
0%
Stage/Level
1
Credits
20
Module Code
CHM1004
Teaching Period
Spring
Duration
12 weeks
- Year 2
Core Modules
Microbial Metabolism and Biocatalysis (20 credits)Microbial Metabolism and Biocatalysis
Overview
1. Aspects of microbial metabolism, especially pertaining to environmental nutrient cycles.
2. Introduction to gene mining from microbial metagenomes
3. Aspects of protein engineering including directed evolution
4. Application of enzymes and proteins to biotechnology applications, including biocatalysis.Learning Outcomes
1. Understand how some recent concepts in bioprocesses have impact across industrial & environmental applications.
2. Appreciate the interdisciplinary nature of modern biotechnology, especially the interplay of microbial metabolism and environmental biotechnology.
3. Be able to translate fundamental science discoveries into technology innovation in the field of biocatalysis.
4. Demonstrate scientific writing skills.
5. Analyse gene/protein sequence data in a biocatalysis context using bioinformatics tools (through lab based learning).
6. Develop critical skills in molecular analysis of microbial proteins and related biochemical pathways that can be applied to solve real world technical problems.Coursework
0%
Examination
60%
Practical
40%
Stage/Level
2
Credits
20
Module Code
BIO2311
Teaching Period
Spring
Duration
12 weeks
Experimental Biochemistry (20 credits)Experimental Biochemistry
Overview
Introduction to the Biochemistry Laboratory, General Laboratory Procedures, Chromatography Techniques, Electrophoresis, Centrifugation in Biochemical Research
Radioisotopes in Biochemical Research, UV/vis, fluorescence and CD spectroscopy, Mass Spectrometry, X-ray crystallography, Protein crystallisation, Biochemical thermodynamics, Biomolecular Interactions, Enzyme Kinetics, Immunological techniques, and Application of computers in biochemistry.Learning Outcomes
Upon successful completion of this module students will be able to:
LO1: Describe and explain the principles and theory of key experimental techniques used in biochemistry
LO2: Develop key practical skills in specific analytical techniques.
LO3: Apply a broad knowledge of theoretical and practical concepts to evaluate the significance of experimental/scientific data.
LO4: Develop problem solving skills.
LO5: Develop communication skills including practical report writing.
LO6: Develop and understanding of Good Laboratory Practice (GLP)Skills
Competence in the laboratory, including the ability to plan and execute an experiment and to evaluate and interpret the resulting data. Competence in critically evaluating experimental data. Awareness of the importance of working safely in the laboratory in accord with Health and Safety protocols and good working practices.
Coursework
100%
Examination
0%
Practical
0%
Stage/Level
2
Credits
20
Module Code
BIO2102
Teaching Period
Autumn
Duration
12 weeks
Molecular Genetics and Bioinformatics (40 credits)Molecular Genetics and Bioinformatics
Overview
This module covers the structure and organisation of prokaryotic and eukaryotic genomes and genes, recombinant DNA technology, gene regulation, epigenetics, genomics, transcriptomics, biological databases and application of these to the study of cancer genetics. This module builds on material covered in Molecular Basis of Life (Level1). Teaching is delivered via lectures and corresponding hands on wet lab and bioinformatics practical work. The course is designed to prepare students for Level 3 courses such as Bacterial Genetics & Genetic Manipulation, and Immunology and Immunotherapy and for the Honours research projects that involve molecular biology and bioinformatics analysis.
Learning Outcomes
On successful completion of this module students will be able to:
LO1: Demonstrate an understanding of the structural features of DNA and RNA and the enzymes involved in genetic information flow
LO2: Demonstrate an understanding of genome maintenance (DNA duplication mechanisms; DNA mutations, damage and repair)
LO3: Demonstrate an understanding of the molecular mechanisms involved in gene expression and translation in Prokaryotes and Eukaryotes systems appreciating the differences between the two systems.
LO4: Evaluate and appreciate the importance of the experimental approach and the practical methodologies employed in molecular biology and bioinformatics platforms
LO5: Discuss the molecular genetics of cancer, NGS and application of NGS to the study of cancer
LO6: Develop independent learning, critical thinking and problem solving ability
LO7: Develop communication skills including report writing.
LO8: Demonstrate competence in specific bioinformatics and laboratory practical and manipulative skills.Skills
Skills you will learn:
(see further information in Practical handouts)
•Basic skills in solution preparation, storage, and usage for molecular techniques
•Agarose gel analysis of DNA
•PCR
•Restriction digestion of DNA
•Purification of DNA
•Cloning of PCR product into plasmid
•Bacterial transformation
•Identification of recombinant bacterial clones
•Plasmid purification
•Bioinformatics analysis of the plasmid sequencing data (NCBI, BLAST)
• Specific bioinformatics skills related to analysis of genome sequencing data
•Specific bioinformatics skills related to MLST and MLSA analysis
•Specific bioinformatics skills related to transcriptomics and differential gene expression analysis
•Safe working within the laboratory environment
•Recording of data and appropriate analysis
•Data presentation and interpretation
•Oral and written communication skills
•Problem solving
•Team working
•Effective assimilation of knowledge and written communication skillsCoursework
50%
Examination
50%
Practical
0%
Stage/Level
2
Credits
40
Module Code
BIO2305
Teaching Period
Full Year
Duration
24 weeks
Advanced Cell Biology (20 credits)Advanced Cell Biology
Overview
This module builds on the fundamental coverage of cell biology that is delivered in pre-requisite module BIO2104 (i.e. cell structure and function from the perspective of individual organelles, and their interactions, and how disease can arise when these break down).
In BIO2304 we focus on cutting edge techniques that can be used to investigate cell function at a variety of levels including:
Cell culture
Fluorescence microscopy
Transmission and scanning electron microscopy
RNAi / CRISPR
Proteomics
Inhibitors and drug development pipelines
We highlight how the use of these tools can provide a better understanding of disease mechanisms and aid the development of new treatment options. Case studies include:
Cancer cell biology
Stem cell research
Neurones and neurotransmittersLearning Outcomes
On successful completion of this module students will be able to:
LO1: Demonstrate an understanding of the theoretical basis of classical and emerging technologies that are used to study cells.
LO2: Appreciate how these tools can provide a deeper understanding of cell function and disease mechanisms.
LO3: Discuss how advances in technology is driving research into new therapeutic strategies for various diseases.
LO4: Appreciate the importance of experimental approach and apply practical cell biology methodologies.
LO5: Demonstrate scientific communication skills including report writing and peer discussion.
LO6: Demonstrate the ability to work as part of a team and reflect on their role in the team.
LO7: Appreciate health and safety in the laboratory and ethical practice.
LO8: Develop independent learning, critical thinking and problem solving ability.Skills
Observation, recording, data analysis, microscopy, image analysis and experimental design. Practical skills in laboratory investigations including use of specialised software in data analysis, professional technical report writing and team-work.
-------------------Coursework
40%
Examination
60%
Practical
0%
Stage/Level
2
Credits
20
Module Code
BIO2304
Teaching Period
Spring
Duration
12 weeks
Cell Biology (20 credits)Cell Biology
Overview
Detailed coverage of cell structure and function from the perspective of individual organelles and their interactions including:
The variety of cells
The cell cycle
Cell Signalling
The nucleus & the cytoplasm
The mitochondrion & energy production
Ribosomes & protein synthesis
The secretory pathway
Exosomes
Membrane pumps and transporters
Cytoskeleton
Blood cells & pathologies
How breakdown of normal organelle function can lead to disease and how a knowledge of cell biology has helped to develop appropriate treatments, e.g.:
Cystic fibrosis
Cancer
Lysosomal storage diseases
Sickle cell anaemiaLearning Outcomes
On successful completion of this module students will be able to:
LO1: Describe the structure and function of the major cell organelles and their interactions with each other
LO2: Demonstrate knowledge of how a better understanding of cell biology can lead to the development of new therapeutic strategies in various disease states
LO3: Appreciate the importance of experimental approach and the practical methodologies employed in cell biology
LO4: Develop independent learning, critical thinking and problem solving abilitySkills
Observation, recording, data analysis, microscopy, basic haematology, image analysis and experimental design. Practical skills in laboratory investigations including use of specialised software in data analysis, professional technical report writing and team-work.
------------------------Coursework
100%
Examination
0%
Practical
0%
Stage/Level
2
Credits
20
Module Code
BIO2104
Teaching Period
Autumn
Duration
12 weeks
- Year 3
Core Modules
Professional Studies (120 credits)Professional Studies
Overview
1. Preplacement preparation including; the selection of placement,
application forms, CV's and interviews. Evaluation of placement by student,
including potential to relate academic theory to the work place, skills
development and project development.
2. On placement work including; relating academic theory to the workplace, recording activities and reflection in a log book. 3. Post placement reflection of learning and career prospects.
1. Preplacement preparation including; the selection of placement,
application forms, CV's and interviews. Evaluation of placement by student,
including potential to relate academic theory to the work place, skills
development and project development.
2. On placement work including; relating academic theory to the workplace, recording activities and reflection in a log book. 3. Post placement reflection of learning and career prospects.Learning Outcomes
On successful completion of this module students will be able to:
LO1: Apply subject knowledge of theoretical and practical concepts to provide solutions in the work-related environment
LO2: Evidence development in work related transferable skills
LO3: Manage and deliver project type work in the workplace setting
LO4: Demonstrate employability skills and an enhanced career plan.
LO5: Demonstrate an understanding of the importance of Health and Safety in the work environment.
LO6: Exhibit effective communication skills in both the academic and work environment.
LO7: Demonstrate the ability to work as part of a team and reflect on your role in the team.
LO8: Evaluate and reflect upon your learning experience in the work environmentSkills
Students will identify and evaluate the skills which they have developed
during the placement, which may include: communication (oral and written); problem-solving; team work; IT; presentational; personal development and reflection.Coursework
100%
Examination
0%
Practical
0%
Stage/Level
3
Credits
120
Module Code
BIO3303
Teaching Period
Full Year
Duration
40 weeks
- Year 4
Core Modules
Biomolecules in Health and Disease (40 credits)Biomolecules in Health and Disease
Overview
The module is focused on the four main classes of biomolecules (nucleic acids, proteins, lipids and carbohydrates) and how these each contribute to the health of organisms and, if dysfunctional, in disease states. Teaching on this module is research-informed, with lecture material delivered by research active experts in each of these fields. Students will examine in depth the structure-function relationships of nucleic acids, proteins and receptor signalling, and will illustrate the importance of the latter as drug targets. The biomolecules in disease states such as cancer will be studied as well as the roles of metals, toxins and plant metabolites in human and animal health and disease..
Learning Outcomes
Students on the course will:
LO1: Evaluate and discuss current principles in biochemistry
LO2: Demonstrate an in-depth knowledge of the chemistry, structure and function of biological molecules, the major classes of signalling molecules, their receptors and intracellular signalling pathways.
LO3: Demonstrate an understanding of the structure and function of both prokaryotic and eukaryotic cells
LO4: Explain the biochemical processes that underlie the relationship between genotype and phenotype
LO5: Explain the complex nature of the pathophysiology of selected biochemical disorders
LO6: Analyse ways of manipulating biochemical systems to prevent or treat disease.
LO7: Apply problem solving skills.
LO8: Employ communication skills
LO9: Demonstrate innovation in science through the application of knowledge.Skills
Critical evaluation of the relevant scientific literature, problem solving skills, written communication skills. Time management.
Coursework
40%
Examination
60%
Practical
0%
Stage/Level
4
Credits
40
Module Code
BIO3304
Teaching Period
Full Year
Duration
24 weeks
Immunology and Immunotherapy (20 credits)Immunology and Immunotherapy
Overview
The module will look at the cellular and molecular aspects of immunology, including the innate immunity, the adaptive immunity, immunoglobulins, generation of diversity, antigen recognition, antigen processing, immunoassay design and role of cytokines in immune responses. The pathogenesis of a selected of immunological disorders and the role of immunity in protection against pathogens and cancer. The module will also explore the area of immunotherapy.
Learning Outcomes
On successful completion of this module students will be able to:
LO1: Evaluate and discuss current principles in immunology
LO2: Demonstrate an in-depth knowledge of elements constituting the innate and adaptive immune systems
LO3: Critically evaluate current immunological methods
LO4: Explain the complex nature of the pathophysiology of selected immunological disorders
LO5: Analyse ways of manipulating the immune system to prevent or treat disease including the role of immunotherapy in cancer treatment.
LO6: Apply problem solving skills.
LO7: Employ communication skills including oral presentations
LO8: Demonstrate innovation in science through the application of knowledge.Skills
Critical evaluation of the relevant scientific literature. Problem solving skills, oral and written communication skills. Time management and effective IT skills for production of poster.
Coursework
100%
Examination
0%
Practical
0%
Stage/Level
4
Credits
20
Module Code
BIO3104
Teaching Period
Autumn
Duration
12 weeks
Microbiome: Biotechnological applications and ‘Omic manipulations
Overview
The objective of this module is to provide an advanced understanding on the recent developments in ‘omic’ tools to study microbiomes and their role in ecosystem function, host health and biotechnological applications. The students will learn the theoretical and applied basis of ‘omic’ tools (e.g. genomics, meta-genomics/bolomics/proteomics) with lectures suited for different pathways. Case studies will be used to enhance the learning outcomes for students by demonstrating how the microbiome tools can be effectively used to study and manipulate communities. Students will also be trained on how to analyse big datasets (omics), identify appropriate bioinformatics pipelines and in the interpretation of results.
Learning Outcomes
LO1 Demonstrate in depth knowledge of microbiome tools
LO2 Critically discuss the strengths and caveats of different tools
LO3 Evaluate and synthesise scientific literature
LO4 Demonstrate the ability to identify knowledge gaps in microbiome-related research
LO5 Apply problem solving skills and identify future strategies
LO6 Demonstrate the ability to analyse datasets and critically interpret the resultsSkills
Problem solving skills, IT skills for basic bioinformatics, critical evaluation of scientific literature and written communication skills
Coursework
40%
Examination
60%
Practical
0%
Stage/Level
4
Credits
20
Module Code
BIO3203
Teaching Period
Spring
Duration
12 weeks
Research Project (40 credits)Research Project
Overview
This module allows students to complete an independent piece of research that is allied to their programme pathway, employment aspirations and specific academic interests. The final year allows choice from a range of specialised topics that are informed and inspired by the research being carried out in the School of Biological Sciences. This module will provide an understanding of how to conduct an independent, hypothesis driven research project. It allows the student to: find, evaluate and synthesise information from a variety of sources; apply their skills of critical analysis to a ‘real world’ research and apply awareness of ethics/legal/policy aspects in context in the field of Biological Science. This module must be passed in order for students to be awarded a BSc Honours Degree.
Learning Outcomes
On successful completion of this module students will be able to:
LO1: Demonstrate the ability to analyse problems in their field, formulate hypotheses, evaluate and apply evidence-based solutions.
LO2: Plan, carry-out and report on a relevant scientific investigation including the application of health and safety procedures and ethical considerations in research.
LO3: Demonstrate critical analysis of literature and data collected either in the laboratory, field or collated from published sources.
LO4: Innovatively apply their skills to tackling relevant scientific problems.
LO5: Demonstrate effective time-keeping, self-management and the ability to work independently.
LO6: Demonstrate an appreciation of the limits and significance of scientific findings.
LO7: Effectively communicate knowledge of the biological sciences to both a scientific audience and the general public.
LO8: Demonstrate understanding of Good Laboratory Practice (GLP).
LO9: Effectively execute laboratory practical and analytical skills.Skills
Plan, carry out and report a relevant scientific investigation. Time-management skills, initiative and independence. Ability to carry out a risk assessment of a project, appreciate the need to work safely and ethically. Effective IT skills, including Word Processing, retrieval of
information from electronic databases, data analysis and where appropriate statistical analysisCoursework
100%
Examination
0%
Practical
0%
Stage/Level
4
Credits
40
Module Code
BIO3308
Teaching Period
Full Year
Duration
24 weeks
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Entry Requirements
Entrance requirements
| A level requirements BBB including Chemistry and Biology + GCSE Mathematics grade C/4 OR ABB including Chemistry and at least one from Mathematics or Physics + GCSE Biology grade C/4 or GCSE Double Award Science grades CC/4,4 + GCSE Mathematics grade C/4. Where A-level Biology, Mathematics or Physics are not offered, A-levels in three other subjects including Chemistry and AS-level Biology would be considered. A maximum of one BTEC/OCR Single Award or AQA Extended Certificate will be accepted as part of an applicant's portfolio of qualifications with a Distinction* being equated to a grade A at A-level and a Distinction being equated to a grade B at A-level. |
| Irish leaving certificate requirements H3H3H3H3H4H4/H3H3H3H3H3 including Higher Level grade H3 in Chemistry and Biology + if not offered at Higher Level then Ordinary Level grade O4 in Mathematics OR H3H3H3H3H3H3/H2H3H3H3H3 including Higher Level grade H3 in Chemistry and at least one from Mathematics or Physics + Ordinary Level grade O4 in Biology + if not offered at Higher Level then grade O4 in Mathematics. |
| Access Course Successful completion of a relevant Science based Access Course (120 credits) with an average of 80% and no less than 70% in any module. A relevant Access Course will normally include a minimum of 60 credits at Level 3 (preferably 80 credits) in appropriate Biology and Chemistry modules (eg: two Chemistry modules + one Biology module) + GCSE Mathematics grade C/4 or equivalent in Access Course. |
| International Baccalaureate Diploma 32 points overall including 6,5,5 at Higher Level including Chemistry and Biology + GCSE Mathematics grade C/4 OR 33 points overall including 6,5,5 at Higher Level including Chemistry and Mathematics or Physics + GCSE Biology grade C/4 or GCSE Double Award Science grades CC/4,4 + GCSE Mathematics grade C/4 Standard Level grade 4 would be acceptable in lieu of the GCSE requirement. |
| BTEC Level 3 Extended/National Extended Diploma Not considered |
Selection Criteria
In addition, to the entrance requirements above, it is essential that you read our guidance below on 'How we choose our students' prior to submitting your UCAS application.
In addition, to the entrance requirements above, it is essential that you read our guidance below on 'How we choose our students' prior to submitting your UCAS application.
Applications are dealt with centrally by the Admissions and Access Service rather than by the School of Biological Sciences. Once your on-line form has been processed by UCAS and forwarded to Queen's, an acknowledgement is normally sent within two weeks of its receipt at the University.
Selection is on the basis of the information provided on your UCAS form. Decisions are made on an ongoing basis and will be notified to you via UCAS. These decisions can only be made on the basis of the information given and applicants must show due care and diligence when completing their applications. In particular, full details must be included about qualifications completed or still to be completed.
For entry last year, applicants for programmes in the School of Biological Sciences must have had, or been able to achieve, a minimum of five GCSE passes at grade C/4 or better (to include English Language and Mathematics), though this profile may change from year to year depending on the demand for places. The Selector also checks that any specific entry requirements in terms of GCSE and/or A-level subjects can be fulfilled.
For applicants offering Irish Leaving Certificate, please note that performance at Junior Certificate is taken into account. For last year’s entry applicants for this degree must have had, a minimum of 5 IJC grades C/Merit, though this profile may change from year to year depending on the demand for places. The Selector also checks that any specific entry requirements in terms of Leaving Certificate subjects can be satisfied.
Offers are normally made on the basis of three A-levels. Two subjects at A-level plus two at AS would also be considered. The minimum acceptable is two subjects at A-level plus one at AS though candidates offering this combination will be considered on an individual basis depending on the degree for which they have applied. The offer for repeat candidates may be one grade higher than for first time applicants. Grades may be held from the previous year.
Applicants offering two A-levels and one BTEC Subsidiary Diploma/National Extended Certificate (or equivalent qualification) will also be considered. Offers will be made in terms of the overall BTEC grade(s) awarded. Please note that a maximum of one BTEC Subsidiary Diploma/National Extended Certificate (or equivalent) will be counted as part of an applicant’s portfolio of qualifications. The normal GCSE profile will be expected.
Applicants offering other qualifications will also be considered. The same GCSE (or equivalent) profile is usually expected of those applicants offering other qualifications.
Those offering a relevant Higher National Certificate (HNC) or Diploma (HND) are considered individually on their own merits for entry to Stage 1. For applicants offering a HNC, the current requirements are successful completion of the HNC with 1 Distinction and remainder Merits. For those offering a HND, at least one of the units completed in the first year of the HND must be at Merit level. Where offers are made students would be expected to achieve Merits in all units assessed in final year. For those offering a HNC or HND, some flexibility may be allowed in terms of GCSE profile.
The information provided in the personal statement section and the academic reference together with predicted grades are noted but, in the case of degree courses in the School of Biological Sciences, these are not the final deciding factors in whether or not a conditional offer can be made. However, they may be reconsidered in a tie break situation in August.
A-level General Studies and A-level Critical Thinking would not normally be considered as part of a three A-level offer and, although they may be excluded where an applicant is taking four A-level subjects, the grade achieved could be taken into account if necessary in August/September.
Applicants are not normally asked to attend for interview.
If you are made an offer then you may be invited to a Faculty/School Visit Day, which is usually held in the second semester. This will allow you the opportunity to visit the University and to find out more about the degree programme of your choice and the facilities on offer. It also gives you a flavour of the academic and social life at Queen's.
If you cannot find the information you need here, please contact the University Admissions and Access Service (admissions@qub.ac.uk), giving full details of your qualifications and educational background.
International Students
Our country/region pages include information on entry requirements, tuition fees, scholarships, student profiles, upcoming events and contacts for your country/region. Use the dropdown list below for specific information for your country/region.
English Language Requirements
An IELTS score of 6.5 with a minimum of 5.5 in each test component or an equivalent acceptable qualification, details of which are available at: http://go.qub.ac.uk/EnglishLanguageReqs
If you need to improve your English language skills before you enter this degree programme, INTO Queen's University Belfast offers a range of English language courses. These intensive and flexible courses are designed to improve your English ability for admission to this degree.
- Academic English: an intensive English language and study skills course for successful university study at degree level
- Pre-sessional English: a short intensive academic English course for students starting a degree programme at Queen's University Belfast and who need to improve their English.
International Students - Foundation and International Year One Programmes
INTO Queen's offers a range of academic and English language programmes to help prepare international students for undergraduate study at Queen's University. You will learn from experienced teachers in a dedicated international study centre on campus, and will have full access to the University's world-class facilities.
These programmes are designed for international students who do not meet the required academic and English language requirements for direct entry.
- Foundation
The INTO progression course suited to this programme is
http://www.intostudy.com/en-gb/universities/queens-university-belfast/courses/international-foundation-in-engineering-and-science.
INTO - English Language Course(QSIS ELEMENT IS EMPTY)
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Careers
Career Prospects
Introduction
Studying Biochemistry at Queen‘s develops the core skills and employment related experiences that are valued by employers, professional organisations and academic institutions – particularly analytical and numerical skills.
Biochemists can gain employment in growth areas such as the biotechnology, food and pharmaceutical industries, biomedical research, the NHS and research and development in academia and industry. Approximately one third of our graduates go on to further study before entering specialist employment.
Although the majority of our graduates pursue careers in the molecular life sciences, significant numbers develop careers in a wide range of other sectors such as science communication, education, legal services, journalism, finance and management. The subject is also widely accepted for graduate entry to medical, dental, veterinary and pharmacy schools – an increasingly common route into these professions, with many universities in the UK and Ireland offering four-year graduate programmes.
Additional Awards Gained(QSIS ELEMENT IS EMPTY)
Prizes and Awards(QSIS ELEMENT IS EMPTY)
Degree plus award for extra-curricular skills
In addition to your degree programme, at Queen's you can have the opportunity to gain wider life, academic and employability skills. For example, placements, voluntary work, clubs, societies, sports and lots more. So not only do you graduate with a degree recognised from a world leading university, you'll have practical national and international experience plus a wider exposure to life overall. We call this Degree Plus. It's what makes studying at Queen's University Belfast special.
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Entry requirements
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Fees and Funding
Tuition Fees
| Northern Ireland (NI) 1 | £4,710 |
| Republic of Ireland (ROI) 2 | £4,710 |
| England, Scotland or Wales (GB) 1 | £9,250 |
| EU Other 3 | £23,100 |
| International | £23,100 |
1 EU citizens in the EU Settlement Scheme, with settled status, will be charged the NI or GB tuition fee based on where they are ordinarily resident. Students who are ROI nationals resident in GB will be charged the GB fee.
2 EU students who are ROI nationals resident in ROI are eligible for NI tuition fees.
3 EU Other students (excludes Republic of Ireland nationals living in GB, NI or ROI) are charged tuition fees in line with international fees.
All tuition fees quoted relate to a single year of study and will be subject to an annual inflationary increase, unless explicitly stated otherwise.
Tuition fee rates are calculated based on a student’s tuition fee status and generally increase annually by inflation. How tuition fees are determined is set out in the Student Finance Framework.
Additional course costs
All Students
Depending on the programme of study, there may be extra costs which are not covered by tuition fees, which students will need to consider when planning their studies.
Students can borrow books and access online learning resources from any Queen's library.
If students wish to purchase recommended texts, rather than borrow them from the University Library, prices per text can range from £30 to £100. A programme may have up to 6 modules per year, each with a recommended text.
Students should also budget between £30 to £75 per year for photocopying, memory sticks and printing charges.
Students undertaking a period of work placement or study abroad, as either a compulsory or optional part of their programme, should be aware that they will have to fund additional travel and living costs.
If a final year includes a major project or dissertation, there may be costs associated with transport, accommodation and/or materials. The amount will depend on the project chosen. There may also be additional costs for printing and binding.
Students may wish to consider purchasing an electronic device; costs will vary depending on the specification of the model chosen.
There are also additional charges for graduation ceremonies, examination resits and library fines.
Biochemistry with Professional Studies costs
Year 1 students are required to buy a laboratory coat at a cost of £10 and may wish to buy an E-Book at a cost of £25.
Students undertake a placement in year 3 and are responsible for funding the costs of travel, accommodation and subsistence, associated with the placement. These costs vary depending on the location of the placement provider. Students may receive payment from their placement provider during their placement year. All students may apply to go on a School Workplace Tour at a cost of £100.
How do I fund my study?
There are different tuition fee and student financial support arrangements for students from Northern Ireland, those from England, Scotland and Wales (Great Britain), and those from the rest of the European Union.
Information on funding options and financial assistance for undergraduate students is available at www.qub.ac.uk/Study/Undergraduate/Fees-and-scholarships/.
Scholarships
Each year, we offer a range of scholarships and prizes for new students. Information on scholarships available.
International Scholarships
Information on scholarships for international students, is available at www.qub.ac.uk/Study/international-students/international-scholarships/.
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Apply
How and when to Apply
How to Apply
Application for admission to full-time undergraduate and sandwich courses at the University should normally be made through the Universities and Colleges Admissions Service (UCAS). Full information can be obtained from the UCAS website at: www.ucas.com/students.
When to Apply
UCAS will start processing applications for entry in autumn 2023 from 1 September 2022.
Advisory closing date: 25 January 2023 (18:00). This is the 'equal consideration' deadline for this course.
Applications from UK and EU (Republic of Ireland) students after this date are, in practice, considered by Queen’s for entry to this course throughout the remainder of the application cycle (30 June 2023) subject to the availability of places.
Applications from International and EU (Other) students are normally considered by Queen’s for entry to this course until 30 June 2023. If you apply for 2023 entry after this deadline, you will automatically be entered into Clearing.
Applicants are encouraged to apply as early as is consistent with having made a careful and considered choice of institutions and courses.
The Institution code name for Queen's is QBELF and the institution code is Q75.
Further information on applying to study at Queen's is available at: www.qub.ac.uk/Study/Undergraduate/How-to-apply/
Terms and Conditions
The terms and conditions that apply when you accept an offer of a place at the University on a taught programme of study. Queen's University Belfast Terms and Conditions.
Additional Information for International (non-EU) Students
- Applying through UCAS
Most students make their applications through UCAS (Universities and Colleges Admissions Service) for full-time undergraduate degree programmes at Queen's. The UCAS application deadline for international students is 30 June 2023. - Applying direct
The Direct Entry Application form is to be used by international applicants who wish to apply directly, and only, to Queen's or who have been asked to provide information in advance of submitting a formal UCAS application. Find out more. - Applying through agents and partners
The University’s in-country representatives can assist you to submit a UCAS application or a direct application. Please consult the Agent List to find an agent in your country who will help you with your application to Queen’s University.
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Fees and Funding