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MSc(Res) Oncology Drug Discovery

Academic Year 2019/20

A programme specification is required for any programme on which a student may be registered. All programmes of the University are subject to the University's Quality Assurance and Enhancement processes as set out in the DASA Policies and Procedures Manual.

Programme Title

MSc(Res) Oncology Drug Discovery

Final Award
(exit route if applicable for Postgraduate Taught Programmes)

Master of Science by Research

Programme Code

MED-MSR-OD

UCAS Code

HECoS Code

100270

ATAS Clearance Required

No

Health Check Required

No

Portfolio Required

Interview Required

Mode of Study

Full Time

Type of Programme

Postgraduate

Length of Programme

1 Academic Year(s)

Total Credits for Programme

180

Exit Awards available

INSTITUTE INFORMATION

Awarding Institution/Body

Queen's University Belfast

Teaching Institution

Queen's University Belfast

School/Department

Medicine, Dentistry and Biomedical Sciences

Framework for Higher Education Qualification Level 
www.qaa.ac.uk

Level 7

QAA Benchmark Group
www.qaa.ac.uk/quality-code/subject-benchmark-statements

N/A

Accreditations (PSRB)

REGULATION INFORMATION

Does the Programme have any approved exemptions from the University General Regulations
(Please see General Regulations)

No

Programme Specific Regulations

Awards, Credits and Programme of Learning Outcomes

The following regulations should be read in conjunction with the University’s General Regulations:

1. Any student who fails 60 credits or more of taught modules will not be able to proceed to the dissertation module until the taught modules are successfully completed. Students can then choose whether to graduate with the Postgraduate Diploma or re-enrol to take the Dissertation in the next academic year.

2. Students who pass all the taught modules (120 CATS) but who either, did not submit or who fail to achieve a mark of at least 50% in the dissertation, shall be eligible for the award of Postgraduate Diploma.

3. Students who have failed to pass all taught modules but who have accumulated a minimum of 60 CATS points will be eligible for the award of Postgraduate Certificate in Oncology Drug Discovery.

Students with protected characteristics

Normally there are no barriers, but as this is a laboratory based subject, each case will be considered individually

Are students subject to Fitness to Practise Regulations

(Please see General Regulations)

No
No (With the exception of students who are taking this as an intercalated degree and whose primary programmes are subject to Fitness to Practise (FTP) regulations) FTP programmes are those which permit students to enter a profession which is itself subject to FTP rules

EDUCATIONAL AIMS OF PROGRAMME

Acquire the background knowledge and lab based skills to further understand the principles of drug discovery and development.

Participate in novel and high-quality research drug discovery projects with the aim of making an impact on the future of healthcare.

Demonstrate scientific writing skills through the write up of their research as a Dissertation and the completion of written course assignments.

Evaluate current and future developments in the drug discovery process from target ID to clinical use and be able to critically assess these processes.

Critically analyse scientific literature and show proficiency in scientific writing of research articles.

Recognise and employ key skills in time management, personal management and team building.

Demonstrate ability to incorporate innovation into project development.

Further develop the capacity for self-directed and life-long learning.

Demonstrate the knowledge and research skills for progression to PhD programmes.

LEARNING OUTCOMES

Learning Outcomes: Cognitive Skills

On the completion of this course successful students will be able to:

Analyze, interpret and appraise experimental data

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Essays
Research Project

Adopt various experimental approaches and combine information from different sources to develop an experimental plan

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Presentations

Assess publically available data sets and outline how they would be useful in their research approach.

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Research project

Evaluate issues in the drug development field

Teaching/Learning Methods and Strategies

Masterclasses
Journal Clubs
Guided Self-Directed Learning
Small Group Learning

Methods of Assessment

Presentation
Written assignment

Demonstrate the ability to write a grant application

Teaching/Learning Methods and Strategies

Tutorials
Workshops

Methods of Assessment

Presentation
Written assignment

Learning Outcomes: Transferable Skills

On the completion of this course successful students will be able to:

Critically evaluate scientific literature

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Written Assignments

Apply analytical, numerical and creative thinking skills

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Presentations

Work independently and take responsibility for own learning

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Research Project

Demonstrate effective oral and written communication skills including the presentation of scientific information

Teaching/Learning Methods and Strategies

Masterclasses

Methods of Assessment

Presentations
Written assignments

Manage time effectively and prioritize tasks

Teaching/Learning Methods and Strategies

Practicals

Methods of Assessment

Research Project

Develop scientific ideas and incorporate innovation

Teaching/Learning Methods and Strategies

Lectures
Tutorials
Thesis

Methods of Assessment

Written Assignment

Develop own knowledge and skills and contribute to the development of others, through active participation in teamwork and group learning opportunities

Teaching/Learning Methods and Strategies

Journal Clubs
Small Group Learning

Methods of Assessment

Presentations

Use information technology with particular emphasis on the recording of information and data retrieval

Teaching/Learning Methods and Strategies

Guided Self Directed Learning
Small Group Learning
Practical's

Methods of Assessment

Written assignments

Apply scientific research principles and audit

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Written assignments

Enhance their Professional and Career Development portfolio

Teaching/Learning Methods and Strategies

Seminars
Masterclasses

Methods of Assessment

Written assignment

Learning Outcomes: Knowledge & Understanding

On the completion of this course successful students will be able to:

Critically analyse and discuss principles of drug discovery process

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Essays

Discuss experimental approaches, techniques and design in their individual projects

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Oral Presentations (PowerPoint)

Understand genomic alterations that lead to cellular phenotype changes in human disease

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Poster Presentations

Discuss the use of biomarkers in disease diagnosis and prognosis and appreciate their role as surrogate markers of drug efficacy and disease response

Teaching/Learning Methods and Strategies

Masterclasses

Methods of Assessment

Written assignments

Outline the principles of clinical trial design and indicate how translational studies can be incorporated into clinical trials

Teaching/Learning Methods and Strategies

Practicals

Methods of Assessment

Written assignments

Critically evaluate current scientific literature.

Teaching/Learning Methods and Strategies

Journal Clubs

Methods of Assessment

Presentations

Discuss and outline how research discoveries may be commercialised for rapid development and translation to new treatments

Teaching/Learning Methods and Strategies

Small Group Learning

Methods of Assessment

Written assignments

Learning Outcomes: Subject Specific

On the completion of this course successful students will be able to:

Critically analyse experimental approaches

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Essays

Explain techniques that will underpin the experimental design of their Research Project

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Oral Presentations

Develop and present a Research Proposal for their Research Project

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Written assignment

Interpret and analyse the results of their Research Project to write a comprehensive dissertation.

Teaching/Learning Methods and Strategies

Masterclasses
Lectures

Methods of Assessment

Project dissertation

Generate a grant proposal with the aim of funding their research proposal

Teaching/Learning Methods and Strategies

Small Group Learning

Methods of Assessment

Oral Presentations
Written assignments

Interpret data to prepare a scientific paper based on established guidelines for a chosen journal

Teaching/Learning Methods and Strategies

Lectures
Tutorials

Methods of Assessment

Written assignments

Explain what makes a good drug target and understand the requirement for the development of companion diagnostics in tandem with innovative drug development

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Written assignments

Discuss the factors that contribute to a high quality clinical trial.

Teaching/Learning Methods and Strategies

Lectures
Tutorials

Methods of Assessment

Presentation

Analyse how new drug targets are identified, validated throughout the drug discovery process and how assays are developed

Teaching/Learning Methods and Strategies

Lectures
Tutorials
Masterclasses
Seminars

Methods of Assessment

Presentation
Written assignments

Critically evaluate new methods for drug delivery

Teaching/Learning Methods and Strategies

Lectures
Tutorials
Masterclasses
Seminars

Methods of Assessment

Presentation
Written assignments

Describe how chemical matter is identified through screening, developed through hit to lead and lead optimization towards clinical use

Teaching/Learning Methods and Strategies

Lectures
Tutorials
Masterclasses
Seminars

Methods of Assessment

Presentation
Written assignments

Demonstrate an understanding of how external factors contribute to the development process, such as market place and commercial outputs

Teaching/Learning Methods and Strategies

Lectures
Tutorials
Masterclasses
Seminars

Methods of Assessment

Presentation
Written assignments

Evaluate the important elements of biomarkers as prognostic and predictors of disease

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Written assignments, Oral Presentations

Demonstrate the ability to use publicly available datasets

Teaching/Learning Methods and Strategies

Masterclasses, Lectures

Methods of Assessment

Written assignments, Project dissertation

Construct a Research report, indicating progress and future plans/directions

Teaching/Learning Methods and Strategies

Guided Self Directed Learning

Methods of Assessment

Written assignments

MODULE INFORMATION

Programme Requirements

Module Title

Module Code

Level/ stage

Credits

Availability

Duration

Pre-requisite

 

Assessment

 

 

 

 

S1

S2

 

 

Core

Option

Coursework %

Practical %

Examination %

Research Project

SCM8067

7

60

YES

YES

24 weeks

N

YES

70%

30%

0%

Dissertation

SCM8068

7

60

YES

12 weeks

N

YES

100%

0%

0%

Cancer Biology

SCM8065

7

10

YES

6 weeks

N

YES

70%

30%

0%

Research Translation: from Concept to Commercialisation

SCM8096

7

20

YES

YES

24 weeks

N

YES

70%

30%

0%

Drug Optimization, Drug Delivery and Clinical Trials

SCM8138

7

10

YES

6 weeks

N

YES

70%

30%

0%

Target Identification and Development in Drug Discovery

SCM8139

7

10

YES

6 weeks

N

YES

70%

30%

0%

Diagnosis and Treatment of Cancer

SCM8144

7

10

YES

6 weeks

N

YES

60%

40%

0%

Notes

Students must take all modules (180 CATS).