Predicitive analytics in an ICU by processing streams of physiological data in real-time
Principal Supervisor: Dr Charles J Gillan
Second Supervisor: Dr Murali Shyamsundar (medicine)
+ Project Description
Researchers at the ECIT Institute at QUB have worked closely with clinical colleagues in the QUB School of Medicine since 2013 to develop a prototype system for predictive analytics on streams of respiratory data from ventilators in an ICU. This PhD project will first of all educate the student in the wider field of high performance predictive analytics and then seek to apply it to the ICU setting. The aim is to generalise the work already done on respiration to other clinical parameters, and combinations of physiological parameters, thereby giving a more complete view of the condition of each monitored patient. This means that research will focus predictive analytics from values provided by several signals.
The monitoring and alert system has to run accurately, 24x7, for all ICU patients being monitored. Patients can arrive on the system and can leave from it at any point in time. Furthermore patients may be disconnected from the monitoring system for finite periods of time.
The project will be jointly supervised by Dr M. Shyamsundar, a QUB clinical academic and an NHS ICU Consultant.
The project will be based in the ECIT Institute and therefore is primarily a project developing research skills in: programming for a mission critical system, concurrent software programming and high performance computing. The student will develop extensive skills including in: C++, C, OpenCL, operating systems, parallel computing, distributed computing, code optimisation, numerical analysis, computational mathematics, databases and computational physiology. The general application is that of data analytics, a field that includes many mathematical methods from the field of statistics.
In order to minimise ethical issues of working with actual patient data, the project at least in the first instance seek to use databases of patient signals publically available. The following paragraphs are provided to give a prospective student a flavour of the kind of work that would be undertaken in the PhD project in so far as processing one physiological signal is concerned. To be clear, the ECG processing reported here is well known and would not in itself be part of the research. This is only an example of the kind of processing an algorithms that would be involved. Much research remains to be done on other physiological parameters.
The MIMIC (Multiparameter Intelligent Monitoring in Intensive Care) Databases contain physiologic signals and vital signs time series captured from patient monitors, and comprehensive clinical data obtained from hospital medical information systems. Within this set of data, the MIMIC III Waveform Database is freely distributed and can be used for research purposes. It contains several ElectroCardioGraph (ECG) traces.
+ How to Apply
Applicants should apply electronically through the Queen’s online application portal at: https://dap.qub.ac.uk/portal/
+ Contact Details
|Supervisor Name:||Dr Charles J Gillan|
The ECIT Institute
Tel: +44 (0)28 9097 1847