Cantwell, Dr Marie M
Keywords: nutrition; cancer epidemiology; colorectal cancer; breast cancer; oesophageal cancer
Marie is a senior lecturer in Nutrition and Cancer Epidemiology and has published extensively on the role of diet and lifestyle on oesophageal carcinoma risk within the Factors
Influencing Barrett’s Oesophagus, Reflux Oesophagitis and Oesophageal adenocarcinoma (FINBAR) study, a population-based case-control study in Ireland. Marie is a member of the Pooling Group for the international collaboration BEACON (Barretts Esophagus and Adenocarcinoma Consortium.
Marie is an invited member of Cancer research UK’s Cancer Prevention Expert Advisory Panel. As such she has participated in a Research Challenge Event to help shape the future of cancer prevention research. This advisory panel includes a small group of opinion leaders with expertise from across a range of disciplines that are identifying the key research and implementation challenges in cancer prevention. These challenges will define the research agenda and priority questions funding.
Marie is an invited member of the National Institutes of Health Research Nutrition and Cancer Infrastructure Collaboration. This collaboration, led by Professor Alan Jackson, aims to being coherence to existing activities in the areas of cancer and nutrition and provide a coordinated framework for future research into these areas. It supports engagement with the wider community of researchers, clinicians and others working in cancer and nutrition and includes patient advocacy groups.
Marie was one of 22 invited experts for the World Health Organisation/ IARC (International Agency for Research on Cancer) to summarise all research regarding red meat/processed meat and cancer; summary published in Lancet Oncology October 2015.
Marie is a member of Cancer Research UK Population and Sciences Epidemiology Grant panel. She has collaborations with researchers at the National Cancer Institute from the Prostate Lung Colorectal Ovarian screening trial, the NIH American Association for Retired Persons (NIH-AARP) cohort and the Polyp Prevention Trial and has published extensively on the role of diet and lifestyle and cancer risk. She is principle investigator on a study to develop a Northern Ireland colorectal polyp register to determine factors associated with polyp recurrence and progression to colorectal cancer. She is QUB PI on a molecular pathology epidemiology study which has shown that colorectal cancer patients with high expression of tumour vitamin D receptor have a reduced risk of colorectal cancer mortality. This important resource which includes patients with complete data on tumour pathology and cancer treatments received is providing important information regarding mechanisms of action that can inform mechanistically driven clinical trials to optimise the efficacy of interventions to improve colorectal cancer survival. This research will ultimately lead to novel personalised interventions in colorectal cancer patients based on their tumour biology and lifestyle characteristics. She is also principle investigator on a 6 month randomised controlled trial of a diet and physical activity intervention in prostate cancer patients treated with androgen deprivation therapy. More recently Marie has begun to examine the relationship between nutritional exposures and breast cancer survival using data from the DietCompLyf study a UK cohort of 3000 breast cancer patients.