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LCI Healthy Controls

Principal Investigator: 


Professor Judy Bradley/ Doctor Katherine O’Neill


Name of the Study:

LCI Healthy Controls

Lung Clearance index measurement in adult healthy controls


Why is this Study important?

Collection of normative multiple breath washout (MBW) data from adults is essential to facilitate analysis for local investigators. Currently we do not have this data. Accurate interpretation of MBW data requires comparison with normative values that are inert gas, equipment and software specific and age matched, in accordance with the consensus statement for inert gas without testing.


What is the Research question/aim?

The project aim is to establish a database of Nitrogen ,ultiple breath washout (N2 MBW) parameters (standard LCI, shortened LCI, phase II slope parameters) in a healthy control adult cohort to enable comparison with disease data.


What the Study involves: 

A one off visit to the NICRF to complete two lung function tests



Who can take part in the Study?

Healthy volunteers aged 18-80, have no respiratory conditions (e.g. asthma) and not taking any respiratory medicine (e.g. inhalers)


Contact Information:

Professor Judy Bradley or Dr Katherine O'Neill for more information: 028 9504 0342,


NI Clinical Research Facility,
U Floor, Belfast City Hospital,
Lisburn Road, Belfast, BT9 7AB

Tel:+44 (0)28 9504 0342

Connect to the NICRF