Dr Yiwei Tian

  • Dr Yiwei Tian

RESEARCH FOCUS

Our overall goal is to enhance the drug delivery through the use of amorphous solid dispersion and lipid-based nanoparticles. Of particular interests are the thermodynamic and kinetic phase behaviours of these systems and associated advanced manufacturing platforms. We are also extremely passionate about moving the design and process of pharmaceutical formulation into a predictive science through the establishment of suitable Process Analysis tools. 

 
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RESEARCH OPPORTUNITIES

Our Open to PhD applications in the following areas:

  • Investigation phase behaviours of drug-polymer blends within hot-melt extrusion
  • The thermodynamic and kinetic understanding of drug-polymer binary systems
  • Development of a nanomedicine for visceral leishmanaiasis
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PUBLIC OUTREACH and key achievements

  • The research is mainly industrial orientated and developed tools are already implemented by the R&D department in some of the largest pharmaceutical companies, for example a novel screening method based on thermodynamic principles has been highly cited in this field: http://dx.doi.org/10.1021/mp300386v

 

 

Research students

PhD Title: Solid State Control of Enantiotropic Drugs Using Twin-Screw Extrusion with Integrated Raman-Based Process Analytical Technology


Name: Philip Lynch
Years of Study: 2016-2019
Country: Northern Ireland

PhD Title: Continuous Generation of Nanoparticles


Name: Shane Cullen
Years of Study: 2017-2020
Country: Northern Ireland

 

PhD Title: End to end continuous manufacture of solid dosage forms


Name: Esther Jacobs
Years of Study: 2017-2021
Country: Northern Ireland

Research at Queen's

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