Research Interests

Open to PhD applications in the field of:

• Nanopharmaceuticals
• Metalic/Gold nanoparticles
• Tumour metabolism
• Tumour microenvironment
• Targeted delivery
• Radiopharmaceuticals
• Radiobiology
• Targeted Immunotherapy

Make a PhD enquiry

Current Research Opportunities

• Countering the proteinase-activated receptor 1 (PAR-1) pro-tumour phenotype using a novel nanotherapeutic approach
• Countering the proteinase-activated receptor 1 (PAR-1) pro-tumour phenotype using a novel nanotherapeutic approach

Public outreach & key achievements

• Prostate Cancer UK funding: https://prostatecanceruk.org/research/research-we-fund/s14-004
• MRC Confidence in Concept – Anti-inflammatory radiosensitising gold nanoparticles for the treatment of prostate cancer
• EPSRC – Nanoengineered microneedle arrays for enhanced plasmonic photothermal therapy of basal cell carcinoma – EP/P034063/1
• EPSRC - Improving patient outcome by integrating the generic with the personal – EPSRC EP/K039342/1
• Research Funder NI overview: https://www.crowdfundinsider.com/tag/dr-jonathan-coulter/
• Materials & Advanced TeChnologies for Healthcare - https://www.qub.ac.uk/schools/SchoolofPharmacy/MATCH/

Research students

Name: Lydia McQuoid
PhD title: Evaluating radiation bystander and abscopal effects conferred by novel nanoparticle formulations
Years of Study: 2022-2025
Country: United Kingdom

Name: Xinyi Liu
PhD title: Elucidating the impact of attenuated CXCR4/CXCL12 signaling in prostate cancer
Years of Study: 2021-2024
Country: China

Name: Bayan Ahmed A Alkhaldi
PhD title: A nanotherapeutic approach to inhibiting hedgehog signaling in brain cancer
Years of Study: 2021-2024
Country: Saudi Arabia

Name: Meabh Doherty
PhD title: Manipulating tumour glycolysis through lactate transport to augment radiation response
Years of Study: 2020-2023
Country: Northern Ireland

Name: Cancan Yin
PhD title: PSMA targeted gold nanoparticles as effective prostate cancer radiosensitisers
Years of Study:2019-2022
Country: China

Name: Tongchuan Wang  
PhD title: Exploiting hyperactive glucose transporters: a targeting mechanism for drug loaded nanoparticles  
Years of Study:2019-2022
Country: China

Alumni: Where are they now

Name: Jie Feng
PhD title: Elevating intracellular oxygen using tumour metabolism suppressing nanoparticles
Years of Study: 2019-2022
Country: China
Current position: Postdoc research fellow – Coulter lab, QUB.

Name: Chris Emerson 
PhD title: Development of a cell cycle computational model predicting outcome to novel nanotherapeutics.
Years of Study:2016-2020
Country: Northern Ireland
Current position: Celerion Clinical Trials - Data programmer

Name: Linsdey Bennie
PhD title: Enhancing the radiosensitivity of prostate cancer using RALA Gold nano-complexes
Years of Study:2016-2019
Country: Scotland
Current position: Scientist at pHion Therapeutics

Name: Dr Natalie Owen
PhD title: Radiation induced inflammatory signalling in prostate cancer: A target for co-functionalised gold nanoparticles
Years of Study:2015-2018
Country: England
Current position: Research Scientist at the Sanger Institute, Cambridge, England.

Name: Dr Shannon O’Neill
PhD Title: Enhancing the radio curability of prostate cancer using the anti-cancer stem cell agent, AD-01, and novel CD44-targeted gold nanoparticles
Years of Study: 2015-2018
Country: Northern Ireland
Current Position: Research scientist at Almac, NI.

 

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Funding

• Prostate Cancer UK – Research Innovation Award: https://prostatecanceruk.org/research/research-we-fund/ria19-st2-008
• Prostate Cancer UK – PhD studentship: https://prostatecanceruk.org/research/research-we-fund/s14-004
• Higher Education Authority – North/South Stage 1 – Collaboration with UCD – Dr Susan Quinn – Title: Targeted gold (Au) nanocomposites as cancer radiosensitisers: https://tinyurl.com/yuyfu6ta
• Invest NI Proof of Concept - TRACER - TaRgeted gold (Au) nanoparticles as CancEr Radiosensitisers
• Research career overview: https://www.researchgate.net/profile/Jonathan_Coulter

Media

• • https://web.microsoftstream.com/video/122373d7-e4f0-48c5-bfc1-3b0ef70eff9e
  • Belfast Live – Grant announcement https://tinyurl.com/yc2e7uur
  • Irish News - https://tinyurl.com/mtz858vh
  • The Mail - https://tinyurl.com/2p8xbf6w