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Dr Grieve's research programme is focused on investigating mechanisms underlying cardiovascular remodelling and dysfunction, with a particular interest in the role of reactive oxygen species, novel peptide hormones, endothelial progenitor cells, and the influence of diabetes.

His group employs a wide range of laboratory techniques, from in vivo physiology to molecular biology and clinical validation, to investigate mechanisms underlying the adaptive but ultimately detrimental changes that occur in various cardiovascular disease states and how these may be modulated towards therapeutic benefit.

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Dr Grieve is open to wide-ranging PhD applications from candidates with a basic science or clinical background.
His fields of interest include;

  • cardiovascular biology
  • pathophysiology
  • pharmacology
Previous research experience is desirable although not essential.

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Research students

PhD Title: Does NOX4 play a key role in direct reprogramming of fibroblasts into endothelial cells and underlie their ability to promote angiogenesis?

Name: Ms Arya Moez
Years of Study: 2015-2018
Country: Afghanistan

PhD Title: Selective targeting of glucagon-like peptide-1 signalling as a novel approach to prevent adverse cardiac remodelling associated with diabetes

Name: Mrs Rawan Abudalo
Years of Study: 2016-2019
Country: Jordan

PhD Title: Does endothelial Nox4 NADPH oxidase play a key role in the development and progression of diabetic cardiac remodelling?

Name: Ms Eleanor Gill
Years of Study: 2016-2019
Country: England

Alumni: where are they now?

Dr Mitchel Tate

PhD Title: Investigation of the effects of the glucagon-like peptide-1 mimetic exendin-4 on cardiac remodelling in diabetes

Years of Study: 2011-2015
Country: England
Current position: Postdoctoral Research Associate, Baker Heart and Diabetes Institute, Melbourne, Australia

Dr Adam Harvey

PhD Title: Mechanisms underlying the interaction between PPARα and NADPH oxidases in the hypertrophic cardiomyocyte

Years of Study: 2009-2013
Country: Northern Ireland
Current position: Postdoctoral Research Associate, University of Glasgow, UK

Dr Declan McLaughlin

PhD Title: Investigation into the mechanism of Nox2 NADPH oxidase-dependent signalling in doxorubicin cardiotoxicity

Years of Study: 2008-2013
Country: Northern Ireland
Current position: Teaching Fellow, Queen’s University Belfast, UK

Research at Queen's

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