Dr Evergren's current research focuses on understanding the molecular mechanisms required for membrane trafficking and receptor-mediated signalling during normal physiology and its contribution to cancer. These are fundamental cellular pathways that regulate processes such as proliferation, migration and tissue remodelling.
It is critical to the better understand how receptors are trafficked subcellularly as this determines whether cell signalling is terminated or sustained. A better understanding of these molecular mechanisms is vital to further our understanding of disease mechanisms where these pathways are deregulated.
Dr Evergren is open to PhD applications in the fields of;
- Receptor signalling
- Membrane trafficking
- Inter-organelle interactions
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PUBLIC OUTREACH AND KEY ACHIEVEMENTS
PhD Title: The role of the ubiquitin E3 ligase Itch in receptor endocytosis and cell signalling
Name: Aidan Seeley
Years of Study: 2015-2018