Science & Formulation
Pharmaceutical Materials Science and Formulation
Design, development and industrial translation of novel systems for patient-focused administration of difficult-to-deliver drugs.
Research in this theme is focused on the design, development and industrial translation of novel systems for patient-focused administration of difficult-to-deliver drugs. Activities are concentrated on the development of formulations to address major global issues around sexual and reproductive health, use of hot melt granulation and polymer extrusion/injection moulding technologies to produce solid dosage forms, multi-layered and targeted drug delivery systems, the use microneedles for transdermal drug delivery, patient monitoring and vaccine delivery, implantable delivery systems and ocular therapeutics.
Research themes and areas of activity
HIV Prevention and Multipurpose Prevention Technologies
Research activities are focused on the design, laboratory-scale manufacturing and testing of sustained release and controlled release drug formulations to address major global issues around sexual and reproductive health.
Solid Dosage Forms
Research activities are focussed on the application of fluidised hot melt granulation and polymer extrusion/injection moulding technologies to produce solid dosage forms, multi-layered and targeted drug delivery systems, dosage systems for the delivery of poorly soluble therapeutic agents, molecular recognition and pre-formulation in and leading to the solid state.
Pharmaceutical Technology
Research activities are focused on design, physicochemical characterisation, pre-clinical evaluation and industrial translation of novel polymeric technologies. Key areas of interest include:
- Transdermal delivery of high drug doses
- Intradermal administration of long-acting therapies
- Delivery systems for HIV treatment and prevention
- Anti-resistance antibiotic delivery systems
- Lymphatic targeting
- Minimally-invasive patient monitoring/diagnosis
- Risk-free vaccination
- Ocular drug delivery
- Implant-forming systems
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