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Nanomedicine and Biotherapeutics

Research Opportunities

Supervisors

  • Nanopharmaceutical
  • Targeted delivery
  • Smart and novel nanomaterials
  • Exosomes
  • Immunotherapy
  • Tumour microenvironment
  • Nanotoxicology.

Dr Wafa Al-Jamal

  • Cancer Research
  • Personalised medicine
  • Biomarkers
  • Novel treatment options

Dr Niamh Buckley

  • Fields of protease biology
  • Inhibitor development (small molecule and biological inhibitors)

Dr Roberta Burden

  • USP17 as a therapeutic target in cancer
  • Targeting bacterial proteases as an antimicrobial strategy

Dr James Burrows

  • Fields of Peptide science
  • Antibiotic resistance
  • Anti-cancer drug development

Dr Tianbao Chen

  • Brachytherapy/gold nanoparticle combinations
  • Solid tumour nanoparticle transport models 

Dr Jonathan Coulter

  • Cancer research
  • Chemoresistance and DNA damage
  • Cell and molecular biology
  • Transcriptomics
  • Biomarker development and drug discovery.

Dr Fiona Furlong

  • Ion Channel modulation
  • Proteases as potential biomarkers and therapeutic targets
  • Infection and inflammation
  • Chronic diseases

Professor Lorraine Martin

  • Development of nanomedicines for cancer
  • Design of non-viral delivery systems

Professor Helen McCarthy

  • Multiscale modelling of bio molecular systems
  • Pharmaceutical Materials
  • Nanostructure to improve targeting and diagnostic applications

Dr Irina Tikhonova

  • Focus on isolation
  • Structural characterisation
  • Evaluation of natural peptides
  • Performing structure-activity relationships to optimize the bioactivity of peptides as a method of rational drug design
  • Investigating the mechanisms of their action

Dr Lei Wang

  • Natural Bioactive peptide discovery
  • Peptide pharmacology
  • Therapeutic peptide design and development

Dr Mei Zhou

Pharmaceuticals Materials Science and Formulation

Research Opportunities

Supervisors

  • Targeted drug delivery
  • Amorphous solid dispersions
  • Hot-Melt Extrusion
  • 3D printing
  • Continuous processing and PAT.

Professor Gavin Andrews

  • Pharmaceutical Materials Science and Formulation
  • Drug Delivery and Biomaterials

Dr Peter Boyd

  • Microneedles/microarray patches
  • Minimally-invasive patient monitoring/diagnosis
  • Transdermal drug delivery
  • Vaccine delivery
  • Photodynamic therapy
  • Nanomedicine delivery
  • HIV treatment and prevention
  • Delivery of therapeutics for tropical diseases and rare condition

Professor Ryan Donnelly

  • Pre-nucleation clusters in the crystallisation of polymorphs
  • Impact of bio-isosteric replacement on the occurrence of multiple crystal forms
  • Tailoring supra-molecular gels for sub-cutaneous injection

Dr Katharina Edkins

  • Novel bioactive biomaterials as implants
  • Implantable (mucoadhesive) drug delivery systems for application to the oral cavity, vagina and eye
  • Novel engineering strategies for improved medical device and dosage form performance

Professor David Jones

  • Novel mucosal delivery of biofilm penetrating antibiotics
  • Vaccine delivery via mucosal routes
  • Novel spray-dried powders for delivery to the lung

Dr Victoria Kett

  • Biosurface Engineering
  • Electrospinning
  • Microfluidics
  • Nanoanalysis
  • Printing of Medicines.

Dr Dimitrios Lamprou

  • Development of new type of materials and devices for drug delivery applications

Dr Eneko Larraneta

  • multi-component pharmaceutical materials (including pharmaceutical cocrystals)
  • Mechanochemical synthesis
  • Enabling formulation strategies
  • Medical device preparation via hot-melt extrusion

Dr Shu Li

  • Formulation, testing and manufacture of controlled release implantable drug delivery devices

Professor Karl Malcolm

  • Injectable implants
  • Micro-/nanoparticle
  • Microneedles,
  • Medical devices for ocular and transdermal applications.

Dr Thakur Raghu Raj Singh

  • Investigation phase behaviours of drug-polymer blends within hot-melt extrusion
  • The thermodynamic and kinetic understanding of drug-polymer binary systems
  • Development of a nanomedicine for visceral leishmanaiasis

Dr Yiwei Tian

Drug Delivery and Biomaterials

Research Opportunities

Supervisors

  • Targeted drug delivery
  • Amorphous solid dispersions
  • Hot-Melt Extrusion
  • 3D printing
  • Continuous processing and PAT

Professor Gavin Andrews

  • Biomaterial design, synthesis and characterisation
  • Host-material inflammatory response (cell biology)
  • Microbiological evaluation of biomaterials

Dr Louise Carson

  • Microneedles/microarray patches
  • Minimally-invasive patient monitoring/diagnosis
  • Transdermal drug delivery
  • Vaccine delivery
  • Photodynamic therapy
  • Nanomedicine delivery
  • HIV treatment and prevention
  • Delivery of therapeutics for tropical diseases and rare condition

Professor Ryan Donnelly

  • Biofilm microbiology
  • Antimicrobial discovery
  • Bacterial protease biochemistry
  • Host pathogen interactions
  • Microbial bio catalysis

Professor Brendan Gilmore

  • Respiratory microbiology
  • Molecular biology
  • Sntimicrobial discovery and repurposing

Dr Deirdre Gilpin

  • Responsive drug delivery
  • Polymer formulation
  • Bacterial-surface interactions
  • Functional coating technologies

Dr Nicola Irwin

  • Novel bioactive biomaterials as implants
  • Implantable (mucoadhesive) drug delivery systems for application to the oral cavity, vagina and eye
  • Novel engineering strategies for improved medical device and dosage form performance

Professor David Jones

  • Peptide-based materials
  • Drug delivery
  • Biomaterials
  • Antimicrobial drug design

Dr Garry Laverty

  • Drug delivery
  • Biomaterials
  • Sensor development
  • SMART materials
  • Medical device enhancement

Professor Colin McCoy

  • Molecular and sensor based diagnostics for infection with a focus on chronic respiratory diseases
  • Role of the airway microbiome in health and disease
  • Bacterial pathogenesis
  • Antimicrobial resistance and assessment of novel antibiotics and delivery methods

Professor Michael Tunney

Infection and Antimicrobial Resistance

Research Opportunities

Supervisors

  • Biomaterial design, synthesis and characterisation
  • Host-material inflammatory response (cell biology)
  • Microbiological evaluation of biomaterials

Dr Louise Carson

  • Respiratory microbiology
  • Molecular biology
  • Sntimicrobial discovery and repurposing

Dr Deirdre Gilpin

  • Biofilm microbiology
  • Antimicrobial discovery
  • Bacterial protease biochemistry
  • Host pathogen interactions
  • Microbial bio catalysis

Professor Brendan Gilmore

  • Primary care
  • Prescribing
  • Older people
  • Medicines optimisation

Professor Carmel Hughes

  • Responsive drug delivery
  • Polymer formulation
  • Bacterial-surface interactions
  • Functional coating technologies

Dr Nicola Irwin

  • Drug delivery
  • Biomaterials
  • Sensor development
  • SMART materials
  • Medical device enhancement

Professor Colin McCoy

  • Currently not accepting PhD applications

Professor James McElnay

  • Molecular and sensor based diagnostics for infection with a focus on chronic respiratory diseases
  • Role of the airway microbiome in health and disease
  • Bacterial pathogenesis
  • Antimicrobial resistance and assessment of novel antibiotics and delivery methods

Professor Michael Tunney

  • Infection and Antimicrobial resistance
  • Materials and Advanced Technologies for Healthcare

Dr Laura Sherrard

  • Biology and genomics of bacteriophages and viruses of archaea
  • Metatranscriptomics of biofilms
  • Horizontal gene transfer in biofilms
  • Antimicrobial discovery
  • Discovery and engineering of biocatalysts

Professor Timofey Skvortsov

Healthcare Delivery and Medicines Optimisation

Research Opportunities

Supervisors

  • Health services research
  • Primary care
  • Prescribing
  • Medicines optimisation
  • Older people

Dr Heather Barry

  • Primary care
  • Prescribing
  • Older people
  • Medicines optimisation

Professor Carmel Hughes

  • Currently not accepting PhD applications

Professor James McElnay

  • Field of medicines use
  • Optimisation in palliative
  • Hospice and end of life care

Dr Carole Parsons