Research Interests

Research projects typically involve

 

• Poorly water-soluble and BCS class 2 drug delivery using nanotechnology
• Biopharmaceuticals, peptides, and large molecules drug delivery using nanotechnology,
• Physicochemical characterization of formulations,
• in vitro cellular testing of drugs and formulations (safety, activity, and proof of concept)
• With potential collaborations on in vivo conceptualization and synthesis of ligands for drug targeting.

 

We collaborate widely with research groups in academia, industry, and research institutes.

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Current Research Opportunities

• Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery

Public outreach & key achievements

Liposomes, lipid nanocapsules and smartCrystals®: a comparative study for an effective

quercetin delivery to the skin

Hatahet T., Morel Mr., Hommoss A., Devoisselle JM., Müller R. H., Bégu S.

International Journal of Pharmaceutics 542 (2018) 176–185

 

Molybdenum cluster loaded PLGA nanoparticles: An innovative theranostic approach

for the treatment of ovarian cancer

Brandhonneur N., Hatahet T., Amela-Cortes Mr., Molard Y., Cordier S., Dollo G.

European Journal of Pharmaceutics and Biopharmaceutics 125 (2018) 95–105

 

Quercetin topical application: from conventional dosage forms toward nanodosage Forms

Hatahet T., Morel Mr., Hommoss A. Devoisselle, J.M., Müller, R.H., Bégu S.

European Journal of Pharmaceutics and Biopharmaceutics 108 (2016) 41-53,

 

Dermal quercetin smartCrystals®: formulation development, antioxidant activity and cellular safety.

Hatahet, T., Morel, M., Hommoss, A., Dorandeu, C., Müller, R. H., Bégu, S.

European Journal of Pharmaceutics and Biopharmaceutics 102 (2016) 51-63,

 

Research students

Name: Siyang Wu
PhD title: Development of nano photothermal therapy for skin cancer
Years of Study: 3
Country: PR China

Name: Hamoud Alotaibi
PhD title: Engineering Biodegradable Photothermal Nanoparticles for Cancer Therapy
Years of Study: 3
Country: PR China

Name: Minao Zhang
PhD title: Molecularly Imprinted Nanoparticles for Cancer Immunotherapy
Years of Study: 1
Country: PR China

Alumni: Where are they now