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Find a PhD Supervisor

Professor Lorraine Martin

School of Pharmacy

Professor Lorraine Martin

School of Pharmacy

The focus of the Martin group is to understand the diverse roles that active proteases play in the progression of chronic airways diseases, such as cystic fibrosis (CF) and chronic obstructive disease (COPD), to include the characterisation of novel cellular proteins and pathways. A key programme of work is the development of therapeutic strategies to combat airways dehydration, a key factor contributing to disease progression, as well as the characterisation of novel biomarkers to aid earlier diagnosis and disease management.

 

Contact info

  • View Academic Profile
  • askmhls@qub.ac.uk
  • @Prof_SLMartin

Research Interests

Open to PhD applications in the field of:

Chronic airways diseases, to include cystic fibrosis, COPD, bronchiectasis & asthma, with a particular emphasis on:

  • Proteases as potential biomarkers and therapeutics targets;
  • Ion channel modulation, airways hydration & mucociliary clearance;
  • Infection and inflammation.

Make a PhD enquiry


Current Research Opportunities

  • Selective targeting of proteases for the treatment of chronic airways disease.
  • Investigation of novel protease-antiprotease imbalances associated with chronic airways disease.

Public outreach & key achievements

  • Vice-Chancellor’s Research Culture Prize (2020)
  • Vice-Chancellor’s announcement
  • BREATH Research Culture video (below)

 

  • Asthma/COPD Project of the Year, NI Healthcare Award, 2019
  • Vice-Chancellor’s Research Impact Prize (2016)
  • Award of €7.7M EU funding for fight against lung disease (BREATH)
  • New Discovery in Combatting Cystic Fibrosis
  • Founding CEO of ProAxsis Ltd
  • Winner of NISP Connect 25K Award

Research students

PhD Title Modulation of ENaC and mucociliary clearance in COPD
Name Emma Carroll
Country 2017-2021
Year of Study  Northern Ireland
   
PhD Title An investigation of the cellular effect of multi-drug combinations in cystic fibrosis
Name Suhad Bani Melhim
Country Jordan
Year of Study  2018-2021
   
PhD Title  Targeting allergen-associated proteases and airways remodeling in allergic asthma
Name Xuan Ouyang
Country China
Year of Study  2019-2022
   
PhD Title 
The inhibition of furin as a strategy for the treatment of cystic fibrosis
Name
Bethany Montgomery
Country Northern Ireland
Year of Study
2021-2024
   
   

Alumni: Where are they now

PhD Title Putting a CAP on ENaC: A mechanism to rehydrate the airways and restore mucociliary function in cystic fibrosis
Name Dr Lisa Douglas
Year of Study 2015-2018
Country  Northern Ireland
Current Position Post-doctoral Research Fellow, School of Pharmacy, QUB
   
PhD Title The design, synthesis and evaluation of novel inhibitors and activity-based probes targeting serine proteases in cystic fibrosis
Name Dr Timothy Ferguson
Year of Study 2012-2015
Country  Northern Ireland
Current Position Head of Chemistry, ProAxsis Ltd.
   
PhD Title The development of an advanced protease capture material for the treatment of chronic wounds
Name Dr Charlene Robb
Year of Study 2011-2015
Country  Northern Ireland
Current Position Regulatory Affairs Officer at Almac Group

 

 


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  • Faculty of Medicine, Health & Life Sciences

  • School of Pharmacy

  • Material and Advanced Technologies for Healthcare 


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97 Lisburn Road,
Belfast, BT9 7BL. 

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