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L.V. Prasad Eye Institute Clinical Trials Unit Conducted the Good Clinical Practices workshops for ENGINE teams
19th and 20th Jan 2022.
Title: Good Clinical Practices in Research, Investigator Responsibilities


Good Clinical Practices (GCP) in Research, Investigator Responsibilities training is organised to ensure those who are involved in the ENGINE project have a globally acceptable standard for the conduct of all four trials (CLEVER, STABLE, THRIFT and ZEAL). It helps the participants to have an overview on the implementation of the research projects as per the principles of GCP.

GCP is an international ethical and scientific quality standard. It guides the design, conduct, record, analyse and report the trials which involve participation of human subjects. Compliance to the GCP standards ensures assurance that the rights, well-being and safety of the subjects are protected. GCP training is an essential aspect of knowledge sharing and learning for all the team members as part of the GCP guidelines. The principles of Declaration of Helsinki and the importance of consistency is reinforced throughout the training.

The role of institutional review boards, principles of GCP, informed consent process, data confidentiality, subject enrolment, safety reporting are included as part of the two-day sessions.

You can download the recordings of the workshop here.

Day 1-

Day 2 -



Prof Kevin Frick Speaks About Health Economics 

Title: Eye Care Economics: Retrospective and Prospective View


Health economics is the comparative analysis of alternate courses of action in view of both costs and benefits (Drummond etal,.1995).The most common types of economic evaluation used are cost-effectiveness analysis, cost-benefit analysis, cost-utility analysis, cost-minimisation analysis. cost effectiveness analysis helps in analysing the impact when there is differential results in the outcomes and the costs for programs. The inputs required to do an economic evaluation is to identify, measure and assign the value and then compare all the costs and consequences of an intervention.

The session on health economics is an introduction to eye care economics in a nutshell and is included as a learning platform to all the ENGINE team.

You can download the recording of the workshop here.



Dr Srinivas Marmamula Speaks About Hyderabad Ocular Morbidity in Elderly Study (HOMES)


Title: An update on Hyderabad Ocular Morbidity in Elderly Study (HOMES)

The number of people living with dementia globally will rise from 50 million in 2017 to 131.5 million by 2050. The majority reside in low and middle-income countries (LMICs), where a 223% increase in the burden of dementia is expected from 2015 to 2050. The elderly, at greatest risk for cognitive disorders, also have the highest prevalence of vision impairment, which affects 2.2 billion persons globally. Proof of a causative association between vision correction and the slowing of cognitive decline is needed to potentiate investment in inexpensive vision care for prevention.

HOMES is an epidemiological study conducted among the residents of old age homes to understand the prevalence and risk factors of Uncorrected Refractive Errors (URE) for distance in elderly residents in 'homes for the aged' in Hyderabad, India. The session is to give an overview of the key findings of the study.

You can download the recording of the workshop here.


Dr Ving Fai Chan speaks about The Theory of Change

Theory of Change will help with a comprehensive description of the need for change and the essential aspects of it in a programme. It facilitates the planning, execution of  a programme seamlessly over due course of the life cycle of a programme. It is a process which drives the execution and helps to achieve the outcomes systematically. The problem tree analysis and the log frame analysis culminates to the concept of theory of change

You can download the recording of the workshop here.


Dr Keshav Kumar J speakas about the Cross cultural issues in Neuropsychological Assessment

The basic cognitive process is common to all human beings. The difference is only in the way it is expressed in different cultures with the influence of the process in culturally-different ways.The influence of different factors of culture on the different domains of cognition is explored. It is required to assess the cultural impact on test performance of the participants.

You can download the recording of the workshop here.


Ms Mirjam Sadik and Ms Quy Linh speak about the Helmet Law Campaign

Helmet Law in Vietnam: The Vietnamese government passed a resolution on mandatory helmet law for all motor cycle drivers and passengers on roads. Asia Injury Prevention Foundation(AIPF) has played an important role in creating awareness on the use of helmet. With more and more collisions on the road, traffic accidents are  one of the major cause of death in South east Asia. Promoting helmets use is one of the important mission of AIPF.

You can download the recording of the workshop here.

Dr Priya Thomas speaks about Early Functional Rehabilitation for Dementia

Dementia is one of significant public health problem among the elderly. Functional rehabilitation help to reduce the functional disability and improve the quality of life. Dementia affects people in different ways and is not in a sequence. Integration of people with dementia to the mainstream community is an important aspect of dementia care. A multidisciplinary team plays an important role in providing the services and improving the health aging to the patients effected with dementia. Adaptation of the strategies for promoting independence among the patients with dementia are essential to facilitate and sustain the benefits.

You can download the recording of the workshop here.