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Find a PhD Supervisor

Professor Ken Mills

School of Medicine, Dentistry and Biomedical Sciences
Ken Mills

Professor Ken Mills

School of Medicine, Dentistry and Biomedical Sciences

Our understanding of the molecular complexity of the aggressive blood cancers Acute Myeloid Leukaemia (AML) and Myelodysplastic Syndromes (MDS) has increased dramatically in recent years; however, the available therapeutic options are limited due to the disease complexity. The research is focused on identifying less intensive and more effective therapies through in silico and in vitro drug screens to identify novel and repurposed agents and dissecting the effects of defective DNA damage and the specific mutations such as SF3B1 or STAG2.

Contact info

  • View Academic Profile
  • askmhls@qub.ac.uk
  • +44 (0)28 9097 2786, +44 (0)28 9097 2136

Research Interests

There are opportunities to investigate molecular mechanisms in myeloid blood cancers including epigenetic alterations, DNA repair deficiency, altered signal pathways to identify therapeutic targets for novel agents or repurposed drugs using drug screens and/or NGS technologies to improve patient outcomes.

Make a PhD enquiry


Public outreach & key achievements

  • UK Crowdfunding first for cancer research at Queen's
  • Research Funder NI

 


Research students

PhD Title Exploring the Molecular Mechanisms of a Loss of Function STAG2 Mutation in Myelodysplastic Syndrome and Acute Myeloid Leukaemia
Country England
   
PhD Title  DNA Damage Repair Deficiency in AML
Country  Ireland 
   
PhD Title  DNA repair in myeloid malignancies
Country  Northern Ireland

 


Alumni: Where are they now

PhD Title Investigating the molecular basis for the progression of myelodysplastic syndromes to acute myeloid leukaemia
Country Northern Ireland
Current Position  Post-doctoral Research Fellow; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
   
PhD Title  The molecular mechanisms of histone deacetylases inhibitors in Acute Myeloid Leukaemia
Country  Scotland
Current Position  Post-doctoral Research Associate, Paul O’Gorman Research Centre, Glasgow University, Glasgow, Scotland
   
PhD Title Identification of Activated Pathways Following Epigenetic Combination Therapies in Myeloid Leukaemia Cell Lines
Country Northern Ireland
Current Position  Post-doctoral Research Fellow, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Scotland
   
PhD Title Molecular analysis of the in vitro effects and it’s potential for for combination therapy in MDS/AML
Country Northern Ireland
Current Position  Trainee Clinical Scientist, Addenbrooke’s Hospital, Cambridge
   
PhD Title Investigating the consequences of SF3B1 K700E
Country Northern Ireland
Current Position
Post-doctoral Research Assistant, CCRCB, Queen’s University Belfast

 

 


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  • Faculty of Medicine, Health and Life Sciences

  • School of Medicine, Dentistry and Biomedical Sciences

  • Centre for Cancer Research and Cell Biology
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