Research Interests
There are opportunities to investigate molecular mechanisms in myeloid blood cancers including epigenetic alterations, DNA repair deficiency, altered signal pathways to identify therapeutic targets for novel agents or repurposed drugs using drug screens and/or NGS technologies to improve patient outcomes.
Public outreach & key achievements
Research students
| PhD Title | Exploring the Molecular Mechanisms of a Loss of Function STAG2 Mutation in Myelodysplastic Syndrome and Acute Myeloid Leukaemia |
| Country | England |
| PhD Title | DNA Damage Repair Deficiency in AML |
| Country | Ireland |
| PhD Title | DNA repair in myeloid malignancies |
| Country | Northern Ireland |
Alumni: Where are they now
| PhD Title | Investigating the molecular basis for the progression of myelodysplastic syndromes to acute myeloid leukaemia |
| Country | Northern Ireland |
| Current Position | Post-doctoral Research Fellow; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria |
| PhD Title | The molecular mechanisms of histone deacetylases inhibitors in Acute Myeloid Leukaemia |
| Country | Scotland |
| Current Position | Post-doctoral Research Associate, Paul O’Gorman Research Centre, Glasgow University, Glasgow, Scotland |
| PhD Title | Identification of Activated Pathways Following Epigenetic Combination Therapies in Myeloid Leukaemia Cell Lines |
| Country | Northern Ireland |
| Current Position | Post-doctoral Research Fellow, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Scotland |
| PhD Title | Molecular analysis of the in vitro effects and it’s potential for for combination therapy in MDS/AML |
| Country | Northern Ireland |
| Current Position | Trainee Clinical Scientist, Addenbrooke’s Hospital, Cambridge |
| PhD Title | Investigating the consequences of SF3B1 K700E |
| Country | Northern Ireland |
| Current Position |
Post-doctoral Research Assistant, CCRCB, Queen’s University Belfast |