Find a PhD supervisor

Centre for Cancer research and Cell Biology

Research Opportunities

Supervisors

  • Integrate molecular and epidemiological data from populations
  • Breast and Prostate cancer
Dr Emma Allott
  • Gynaecological Cancer
  • Surgical Gynaecological research
Dr James Beirne
  • Technology/platform-agnostic prior knowledge transfer 
  • Compositional statistics
  • Pre-clinical model selection/characterisation
  • Prognostic/predictive subtyping
  • Consensus/meta-clustering
  • Landmark analysis
  • Progression routes from pre-malignancy to cancer
  • Mixed signal deconvolution/convolution
Dr Jaine Blayney
  • Metastatic progression
  • Pre-metastatic organ microenvironment
  • Pathophysiology of cancer
  • Microvascular function and tissue regeneration
  • Remodelling resulting from both disease and treatments
Dr Cristina Branco
  • Mechanisms of radioresistance
  • Drug radiotherapy combinations
  • In vivo models and small animal radiotherapy
  • Nanoparticle theranostics
Dr Karl Butterworth
  • Radiobiology of targeted radionuclides (Radium-223)
  • Clinical trials
  • Stereotactic Radiotherapy
  • Radiation Biology
  • Prostate Cancer
Dr Aidan Cole
  • Cancer clinical trials
  • Basic scientific and translational investigation of mechanisms of treatment resistance
Dr Vicky Coyle
  • Investigate molecular mechanisms involved in dysregulation of the ubiquitin proteasome system in multiple myeloma
  • Identify opportunities for therapeutic intervention
Dr Lisa Crawford
  • Receptor signalling
  • Membrane trafficking
  • Inter-organelle interactions
Dr Emma Evergren
  • Developing clinical biomarker strategies in cancer
  • Using comprehensive genomic approaches to detect DNA alterations
Professor David Gonzalez de Castro
  • DNA damage repair
  • Transcriptional regulation
  • Mechanisms of sensitivity/resistance to DNA damage based therapeutics
Professor Paul Harkin
  • Identifying novel predictive and prognostic biomarkers for radiotherapy treatment in prostate cancer
Dr Suneil Jain
  • Digital molecular pathology approaches to characterize the immune contexture of cancers using high quality bio samples
  • Investigating the role of the oral microbiome in cancer risk and malignant transformation
  • Identifying and validating molecular biomarkers for stratification of patients with cancers
Dr Jacqueline James
  • Characterisation of a molecular group in solid cancers that represents an innate immune response to DNA damage through the STING pathway
  • Development of a gene expression based biomarker panel that can identify pathways related to the hallmarks of cancer and guide patient therapy
Professor Richard Kennedy
  • Investigate key processes involved in the underlying biology driving epigenetic alterations
  • Nucleotide metabolism in cancer development
  • Novel drug targeting of these processes through in vitro cell line-based models and in vivo cancer mouse models
Dr Melissa LaBonte Wilson
  • Cancer biology
  • Cell death
  • Drug resistance
Professor Daniel Longley
  • Integrative analytics & software design
  • Insights into patient heterogeneity
  • AI and Machine Learning
Dr Daragh McArt
  • Characterisation of a molecular group in solid cancers that represents an innate immune response to DNA damage through the STING pathway
  • Development of a gene expression based biomarker panel that can identify pathways related to the hallmarks of cancer and guide patient therapy
Dr Nuala McCabe
  • Benign or malignant urology
  • Ion channels in health and disease
Dr Karen McCloskey
  • Transcription dysfunction in disease
  • Functional genomics and integrative bioinformatics
  • Identification of novel genomically informed treatment strategies
Dr Simon McDade
  • Improved understanding of tumour initiating events in BRCA mutation carriers
  • Investigation and management of breast cancer risk
  • Development of treatment biomarkers in the pre-surgical setting
Dr Stuart McIntosh
  • Modelling responses to radiotherapy, including
  • Proton Relative Biological Effectiveness
  • Intrinsic radio sensitivity
  • The impacts of intercellular communication on radiation responses
Dr Stephen McMahon
  Professor Ian Mills
  • Investigations into molecular mechanisms in myeloid blood cancers including epigenetic alterations
  • DNA repair deficiency
  • Altered signal pathways to identify therapeutic targets for novel agents or repurposed drugs using drug screens and/or NGS technologies to improve patient outcomes
Professor Ken Mills
  • Transcriptional control
  • Signal transduction
  • Chromatin remodelling and epigenetics
  • DNA damage signalling
  • Cell Senescence
  • Molecular cell biology
  • Biochemistry
Dr Paul Mullan
  • Cancer predisposition genetics
  • Molecular pathology
  • Functional genetics
Dr Nick Orr
  • Bone-seeking radionuclides in prostate cancer
  • New therapeutics in CRPC
  • Advanced radiotherapy in prostate cancer
  • Genomic stratification in prostate cancer
Professor Joe O'Sullivan
  • Systems Medicine, Network Biology, Precision Medicine; with applications to cancer biomedicine.
  • Funded PhD studentship 2019-2022, project title: Precision Diagnostics For Novel Cancer Patient Journey-wide Phenotypes
Dr Ian Overton
  • STING pathway across cancers
Dr Eileen Parkes
  • Optimization of bone-seeking radionuclides for targeted molecular radiotherapy
  • Defining stem-cell mediated radio resistance in recurrent brain tumours
  • Building a biological-based rationale for the use of particle-based radiotherapies
  • Understanding Radiation-induced bystander and abscopal responses
  • Defining Next generation laser-produced ion-beams for advanced radiotherapy
Professor Kevin Prise
  • Cellular DNA damage response system and its link with cancer development
Dr Kienan Savage

 

Professor Manuel Salto-Tellez
  • Nano medicine
  • Antibody therapeutics
  • Proteases and pancreatic cancer
Professor Christopher Scott
  • Chromatin remodelers
  • Epigenetics
  • Cancer metastasis
  • Proteomics
  • Molecular cell biology
  • Biochemistry
Dr Adone Tielenius Kruythoff-Mohd Sarip
  • Laboratory based investigation of novel drugs and biomarkers
  • Discovery of resistance mechanisms to therapy
  • Innovative biomarker development using clinical samples
Dr Richard Turkington
  • Laboratory based investigations into molecular mechanisms including altered pro-survival signalling pathways in RASMT and BRAFMT CRC
  • Discovery of novel resistance mechanisms to therapy mechanisms in RASMT and BRAFMT CRC
  • Innovative biomarker development using samples from RASMT and BRAFMT CRC patients
Dr Sandra Van Schaeybroeck
  • Development of Novel Cathepsin V inhibitors to Validate role in Breast Cancer
  • Testing of Epigenetic Probes in Cancer Immune Cells
  • Design, synthesis and SAR exploration of Novel LSD1 inhibitors
Dr Richard Williams

Centre for Public Health

 

Research Opportunities

Supervisors

  • Cancer epidemiology
  • Autoimmune conditions in particular pernicious anaemia
Dr Lesley Anderson
  • Primary and secondary research on visual disorders
Professor Augusto Azuara-Blanco
  • Novel methodological approaches for cancer survival analysis
Dr Finian Bannon
  • Use of systems approaches
  • Analytics/intelligence and modelling to improve the quality and safety of health and social care
Dr Declan Bradley
  • Epidemiology
  • Pharmacoepidemiology
Dr Christopher Cardwell
  • Improving the quality and usefulness of trials and reviews
  • Conducting health services research more generally
  • Conducting research relevant to humanitarian emergencies
Professor Mike Clarke
  • Data analysis
  • Epidemiology projects related to oesophageal or colorectal cancer and pre-malignant conditions
Dr Helen Coleman
  • Strategies to correct and prevent myopia among children in low-resources areas of LMICs
  • Measuring early outcomes in cataract surgery in underserved areas
  • Improved care for complex diseases such as glaucoma and diabetic eye disease in rural Asia
Professor Nathan Congdon
  • Mental Health
  • Ageing
  • Co-morbidity/Multi-morbidity
  • Social determinants of health/social environment
  • Subjective well-being
Dr Sharon Cruise
  • Development and evaluation of health services and public health interventions
  • Implementation science and improvement science
  • Integrated health and social services
  • Service organization and delivery
Professor Michael Donnelly
  • Stem cells and regenerative therapies
  • Orofacial pain
  • Minimal intervention dentistry
  • Oral infections and systemic health
Dr Ikhlas El Karim
  • Patient reported outcomes data on 35,000 prostate cancer patients from the UK
  • Excellent data of all cancer patients diagnosed since 1993
  • Databases on premalignant disease and PSA database
  • Stroke registry to be established
  • Possible cardiovascular in future
Dr Anna Gavin
  • Ophthalmic epidemiology
  • Optometry
  • Vision science
  • Psychophysics
  • Ophthalmology
Dr Ruth Hogg
  • The role of social networks and network interventions for behaviour change
  • Developing and investigating the public health impact of population level built and social environment interventions
Dr Ruth Hunter
  • Opportunities in life-course epidemiology and methods, complex public health interventions and decision sciences

Professor Frank Kee

  • Cancer Epidemiology
  • Pancreatic cancer
  • Early detection of cancer

Dr Andrew Kunzmann

  • Blindness prevention
  • Paediatric palliative care
Dr Lynne Lofield
  • Social science or clinical background
Dr Aideen Maguire
  • Large scale genomics of chronic kidney disease including genome-wide and epigenetic association studies
  • Clinical epidemiology of chronic kidney disease
  • Decision making and conservative management of end-stage renal disease
  • Medical education projects with focus on intravenous fluid therapy
Professor Peter Maxwell
  • Epidemiology
  • Rare disease, research methodology, health service research and network analysis. 
Dr Helen McAneney
  • Development and implementation of psychological interventions for people with neurodegenerative illness
  • Implementation of quality improvement programs in palliative care
  • Development and implementation of healthcare quality inspection techniques
  • Development and implementation of evidence-based interventions for reduction of loneliness among older people
Dr Noleen McCorry
  • Nutrition and ageing research
  • Data analysis in cohort studies and clinical/community - based dietary interventions 
Dr Claire McEvoy
  • Behaviour change interventions focusing on diet and/or obesity across a range of population groups
  • Obesity management
  • Preconception health for men and women - improving health status before pregnancy
Dr Laura McGowan
  • Dementia research including the role of nutrition and inflammation in neurodegeneration
  • The utility of EEG and MEG in assisting diagnostics
  • Large data analytics projects
Dr Bernadette McGuinness
  • Diabetic complications
  • Biomarker discovery
  • Stratified Medicine
Dr Gareth McKay
  • Improving oral health for care home residents
  • Exploring links between oral health and nutritional wellbeing
  • Improving care for head and neck oncology patients
Dr Gerry McKenna
  • Nutrition and prevention/management of obesity
  • Diabetes and cardiovascular disease
Dr Michelle McKinley
  • Genetic-epigenetic-transcriptomic association studies for kidney disease.
  • Multi-omic risk factors for rare disease, and common diseases with a focus in aging populations. 
  • Information and communication provision for kidney disease and rare disease(s).
Dr Amy Jayne McKnight
  • Discrete choice models
  • Secondary data analysis
  • Longitudinal data
Dr Vikki O'Neill
  • Research on administrative data related to ageing, pensions, poverty at older ages
  • Research on looked after children or children known to social services.
Dr Dermot O'Reilly
  • Translational Research 
  • Risk Factors and Biomarkers in the various dementia syndromes
Dr Peter Passmore
  • Ophthalmic image analysis
  • Diabetic retinopathy screening
  • Epidemiology of eye diseases in different populations around the world
Professor Tunde Peto
  • Physical Activity
  • Sedentary behaviour and exercise in school, workplaces or with older adults
Dr Mark Tully
  • Nutrition, particularly dietary intervention studies
  • Projects involving innovative dietary assessment and behaviour change interventions
Professor Jayne Woodside

The Wellcome-Wolfson Institute For Experimental Medicine

 

Research Opportunities

Supervisors

  • Critical care studies that include studies conducted within and after ICU; ICU survivorship; trial methodology studies
Professor Bronagh Blackwood
  • Airway Clearance
  • Exercise and rehabilitation
  • Methods for optimizing clinical trials
Professor Judy Bradley
  • Signal transduction
  • Molecular cell biology
  • Mouse models of disease and drug discovery targeting Grem1 and other proteins involved in human disease
Dr Derek Brazil
  • Epithelial biology;
  • Immunology
  • Microbiology
Dr Eric Campbell
  • Innate immunity
  • Cell and molecular biology
  • Retinal pathophysiology
Dr Mei Chen
  • Microvascular biology and disease
  • Pharmacological
  • Gene therapy-based approaches
Professor Tim Curtis
  • To study the role of the histamine four receptor in the regulation of neutrophil phagocytosis 
  • To study the role of acidic pH in the regulation of anti-microbial functions of neutrophils
Dr Karim Dib

 

Dr Yvonne Dombrowski
  • Cystic fibrosis
  • Bronchiectasis
  • Pneumonia

Dr Damian Downey

  • Harnessing inflammation for repair and regeneration in dental tissues
  • neuronal-immune cells signalling in inflammatory and neuropathic pain
  • Investigate potential links between oral bacteria, systemic inflammation and cardiovascular disease
Dr Ikhlas El Karim
  • Immunology
  • Neuroscience
  • Stem/Progenitor cell biology
  • Tissue regeneration
  • Neuroinflammation
  • Demyelinating diseases
Dr Denise Fitzgerald
  • Cardiovascular biology
  • Pathophysiology
  • Pharmacology
Dr David Grieve
  • Non-adherence in asthma
  • Stratified Medicine / Personalised medicine
  • Health informatics / Health economics

Professor Liam Heaney 

  • Host-pathogen interactions
  • vaccinology
  • pharmacology
Dr Beckie Ingram
  • Investigation of the role of MSC exosomal miRNAs in epithelial and endothelial repair in ARDS
  • The role of MSC mitochondrial transfer in lung regeneration
  • The role of apoptosis in MSC therapeutic effects in ARDS

Dr Anna Krasnodembskaya

  • Multidisciplinary environment to combine molecular, morphological and clinical approaches.
Dr Imre Lengyel
  • Biomedical informatics (translational bioinformatics and exposome informatics)
  • Integration of clinical and molecular data
  • Analysis and representation of exposome data
Dr Guillermo Lopez Campos
  • Various aspects of infection, pain and inflammation in the oral cavity and upper respiratory tract
Dr Fionnuala Lundy
  Dr Andriana Margariti
  • Cardiovascular medicine
  • Ophthalmology
  • Regenerative medicine

 Dr Denise McDonald

  • Neuroinflammation and airways disease
  • Early life influences on adult respiratory health
  • Cohort studies in Early COPD
  • Phase II/III Clinical trials in cough, asthma and COPD
Professor Lorcan McGarvey
  • Improving the diagnosis of serious infection in hospitalised patients
Dr Ronan McMullan
  • Vascular stem cell biology
  • Diabetic retinopathy
  • Diabetic vascular complications
  • Cellular senescence
  • Angiogenesis

 Dr Reinhold Medina

  • Proteomics – to identify protein-protein interactions in rhinovirus-infected cells
  • Molecular cell biology/biochemistry – to understand the role of cellular proteins in rhinovirus replication

Dr Aurelie Mousnier

  • Molecular, cellular, genetic and disease models of inflammation and inflammatory diseases 
  • Identifying novel diagnostics and new therapeutic strategies in the treatment of inflammatory diseases. 
Professor Paul Moynagh
  • Pharmacology
  • Spatiotemporal aspects of GPCR signalling
  • Pathophysiology
Dr Bianca Plouffe
  • Respiratory syncytial virus biology, pathogenesis, and vaccines.
  • Paramyxovirus vaccine vectors, in particular Sendai virus.
  • Culture and exploitation of well-differentiated primary human airway epithelium cell cultures.

 Dr Ultan Power

  • Cellular microbiology of bacterial respiratory pathogens
  • Functional genomics of bacterial virulence factors
  • Subversion of innate immune cells by infection
  • Proteomics approaches to study signalling at the pathogen-host interface
Dr Gunnar Neels Schroeder
  • Epithelial biology
  • Pathophysiology
  • Biomarkers of diseases
  • Bioinformatics
Dr Bettina Schock
  • Lung microbiome
  • Aerosol therapy in critical care
  • Prevention of post-operative pulmonary complications
  • Mechanistic studies to understand pulmonary inflammation and injury

Dr Murali Shyamsundary

 
  • MicroRNAs – their role in gene regulation and use as biomarkers
  • Transcriptomics - RNA-Seq, including single cell analysis
  • Microbial DNA sequencing
Dr David Simpson
  • Harnessing ECFCs to repair choriocapillaris during geographic atrophy
  • The role of the placental growth factor pathway in age-related retinal disease
  • Metabolic plasticity of retinal cells in ischaemia and the potential to regulate physiological angiogenesis
  • Identifying key molecular mechanisms underpinning ECFC dysfunction in diabetic microvascular disease.
  • Development of vascular stem cell therapy for ischaemic retinopathy
  • Combinatorial cell therapy for reversing tissue ischaemia
  • The potential of iPS cell technology to understand mechanisms underpinning patient responsiveness to anti-VEGF agents for diabetic macular oedema

 Professor Alan Stitt

  • Dysregulated protease activity in acute and chronic lung disease
Professor Cliff Taggart
  • Molecular mechanisms of intrinsic multi-drug antibiotic resistance
  • Biogenesis of the Gram-negative bacterial outer membrane, especially lipopolysaccharide and cell wall peptidoglycan
  • Cellular microbiology of opportunistic; Gram-negative bacterial pathogens in phagocytic cells.
Professor Miguel A. Valvano
  • Heart failure, Cardiomyopathy, Cardiac remodelling
  • Diabetes, Hypertension, Ischaemia
  • Biomarkers, Epigenetics, Fibrosis
  • Global Health, mHealth

 Dr Chris Watson

  • Innate immunity
  • Repair and regeneration
  • MiRNA function
  • Transcriptomics in the field of acute and chronic lung inflammation and disease
Dr Sinéad Weldon
  • Immunology
  • Cell and molecular biology
  • Retinal pathophysiology
  • Pharmacology
Professor Heping Xu

Centre for Medical Education

 

Research Opportunities

Supervisors

 

Professor Tim Dornan
  • Simulation based education
  • Medical Education
  • OSCEs
Professor Gerry Gormley
  • Medical education in the General Practice setting
  • Transformative learning
  • Safe care and quality improvement in healthcare
  • Novel platforms for medical education
Dr Nigel Hart
  • Medical education, using qualitative methodologies
Dr Jenny Johnston
  • Haematology

Professor Mary Frances McMullin

Queen's University Belfast is committed to Equality, Diversity and Inclusion.
For more information please read our Equality and Diversity Policy.

Queen's University Belfast is registered with the Charity Commission for Northern Ireland NIC101788
VAT registration number: GB 254 7995 11