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  • Research in the School of Medicine, Dentistry and Biomedical Sciences
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Find a PhD Supervisor

Dr Anna Krasnodembskaya

School of Medicine, Dentistry and Biomedical Sciences
Dr Anna Krasnodembskaya

Dr Anna Krasnodembskaya

School of Medicine, Dentistry and Biomedical Sciences

Krasnodembskaya’s research group works with Mesenchymal Stem Cells (MSCs) with the  particular focus  on the MSC based   cell therapy for Acute Respiratory Distress Syndrome (ARDS). ARDS constitutes a  spectrum of severe acute respiratory failure and is leading cause of morbidity and mortality in critically ill patients with no available pharmacological treatment.

Our central goal is to understand how MSCs work in the context of the injury microenvironment, how MSCs modulate reparative capacities of the host cells and if we can enhance MSC therapeutic potential. More recently we became interested in therapeutic potential of MSC-derived extracellular vesicles as a potential cell-free therapy.

Contact info

  • View Academic Profile
  • askmhls@qub.ac.uk
  • +44 (0)28 9097 6386

Research Interests

Open to PhD applications in the field of

  • Investigation of the role of MSC exosomal miRNAs in epithelial and endothelial repair in ARDS
  • The role of MSC mitochondrial transfer in lung regeneration
  • The role of apoptosis in MSC therapeutic effects in ARDS

Make a PhD enquiry


Current Research Opportunities

  • Exploration of the impact of aging and senescence on angiocrine functions of pulmonary endothelium and therapeutic potential of cell based therapies

Public outreach & key achievements

  • 2017 STEM CELLS Young Investigator Award Winner: Anna D. Krasnodembskaya

  • DNA of Innovation Vol.5


Research students

PhD Title Exploring the therapeutic potential of mesenchymal stem cells in a model of chronic inflammatory lung disease
Country UK
   
PhD Title  ‘Role of SOCS proteins in Mesenchymal Stem Cells’ modulation of macrophages in Acute Respiratory Distress Syndrome’
Country  UK
   

 


Alumni: Where are they now

PhD Title Human Mesenchymal Stromal Cell Regulation of Pulmonary Macrophage Populations in the Acute Respiratory Distress Syndrome
Country UK
Current Position  Research and Development Scientist at XENOBICS LTD
   
PhD Title  ‘Effects of hypercapnic acidosis on the primary cells relevant to Acute Respiratory Distress Syndrome pathophysiology and the therapeutic potential of Mesenchymal Stem Cells’
Country  UK
   

 

 


Discover More

  • Faculty of Medicine, Health and Life Sciences

  • School of Medicine, Dentistry and Biomedical Sciences
  • Wellcome-Wolfson Institute For Experimental Medicine

     


Postgraduate research
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