Dr Linda Stewart

RESEARCH FOCUS

Dr Linda Stewart research focuses on the following;

(i) Development of rapid diagnostics for the detection of bacterial pathogens.Involves:biomarker discovery; binder generation, including polyclonal, monoclonal and recombinant antibodies, and peptide binders; binder characterisation and epitope mapping. Bacterial targets include Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium avium subsp. paratuberculosis, Salmonella, Campylobacter, Escherichia coli Bacteroides fragilis. Detection platforms include lateral flow, biosensors, latex agglutination, ELISA, microfluidics, raman spectroscopy

(ii) The microbiome: specifically, Bacteroides fragilis and its role in health and disease.

(iii) Antimicrobial resistance and the discovery of novel antimicrobials

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RESEARCH OPPORTUNITIES

Open to PhD applications from those with at least a 2.1 degree (or equivalent) in the biological/veterinary/medical sciences and interested in infectious disease, parasitology, functional genomics and the exploitation and development of new ‘omics’ technologies for drug discovery/disease control.   

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Research Students

Phd Title: Development and evaluation a paper-based microfluidic device to detect and differentiate Mycobacterium tuberculosis


Name: Brendan Gilbride 

Phd Title: Evaluation of natural products as alternative antimicrobial agents


Name: Quan Wang

Phd Title: Development of a Raman Spectrometric based Rapid Diagnostic Assay for the detection and differentiation of Tuberculosis


Name: Matthew Ellis 

Phd Title: Production of phage display derived peptide binders specific for Mycobacterium tuberculosis complex organisms


Name: Bhavya Mudgal 

Alumni: where are they now?

Dr Lorna O’Brien 


Novel Detection Methods for Mycobacterium avium subsp paratuberculosis: development, optimisation and field validation. Currently working as a post-doctoral researcher with the School of Veterinary Medicine in University College Dublin on a project entitled ' Investigation of respiratory disease on Irish pig farms, associated risk factors, and the relationship with performance, welfare and antimicrobial use'

Jessica Fletcher


Immunological methods for the Identification and Detection of Mycobacterium bovis Infection. Currently a PhD student in Dublin Dental University Hospital (TCD), under the supervision of Dr Derek Sullivan and Dr Gary Moran on a project using CRISPR to knock out genes in Candida albicans.

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