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Our research interest is to decipher the molecular mechanisms linking nutritional signalling (e.g. high-fat and high-carbohydrate diet) with the onset of chronic metabolic disease, including insulin resistance, non-alcoholic fatty liver disease, cardiovascular disease and inflammatory bowel disease. Our long term goal is to apply multidisciplinary approaches (e.g. Crispr/cas9 and gene sequencing) that interface lipid and carbohydrate metabolism and gut microbiome to identify pharmaceutical targets and functional foods that may land supports for the prevention and treatment of metabolic syndrome.

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In addition to our ongoing research program, we are interested in working with bioinformatics scientists, at all career stages, to resolve questions in gene sequencing profiles. We welcome applications from prospective PhD students who are interested in our work. 

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  1. Invited conference speaker: Akkermansia Muciniphila Ameliorates Inflammatory Bowel Disease via Improvement of Gut Tight Junction and Intestinal Epithelial Cell ER Stress. 6th World Congress on Targeting Microbiota, Porto, Portugal (2018). 
  2. Conference presentation: Cheng X., Harris E., Cui J. and Q. (Senior author) (2018). Diabetes Accelerates Progression of NAFLD to Liver Fibrosis via the Mediation of MicroRNAs. Keystone Symposia-Drivers of Type 2 Diabetes: From Genes to Environment, Seoul, South Korea.
  3. Conference presentation: Wang H. and Q. (Senior author) (2018). Akkermansia Muciniphila Ameliorates Metabolic Inflammation and Insulin Resistance by Regulating LDL Receptor and TMAO Metabolism. Young Microbiologist Symposium-2018, Belfast, UK.






Faculty of Medicine, Health and Life Sciences

School of Biological Sciences

Research Students

Phd Title: Dietary Saturated Fat Induces Inflammatory Bowel Disease via Mediation of CREBH and Gut Microbiome

Name: Henry Wade

Years of Study: Year 1

Country: United Kingdom

Phd Title: Diabetes Accelerates Progression of NAFLD to Liver Fibrosis via the Mediation of MicroRNAs

Name: Hao Wang

Years of Study: Year 1

Country: China

Phd Title: Crispr/Cas9 and MicroRNA-Based Approaches for Determining the Pathogenesis Of Non-Alcoholic Fatty Liver Disease (NAFLD) and Inflammatory Bowel Disease (IBD)

Name: Szczepan Kaluzny

Years of Study: Year 1

Country: Poland


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