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Find a PhD Supervisor

Dr. Bianca Plouffe

School of Medicine, Dentistry and Biomedical Sciences

Dr. Bianca Plouffe

School of Medicine, Dentistry and Biomedical Sciences

G protein-coupled receptors (GPCRs) represent the largest family of proteins targeted by pharmaceutical industry as they regulate many cellular functions. Classically, GPCRs signal at the plasma membrane. Their internalisation leads to signalling arrest. However, recent studies revealed that upon internalisation, some GPCRs signal from intracellular compartments leading to sustained signalling far from plasma membrane.

This differential spatiotemporal signalling mediates unique cellular functions exploitable for novel pharmacological treatments. Dr. Plouffe’s research programme aims to tackle important questions underlying this signalling mode.

Contact info

  • View Academic Profile
  • askmhls@qub.ac.uk

Research Interests

Open to PhD applications in the field of

  • Pharmacology
  • Spatiotemporal aspects of GPCR signalling
  • Pathophysiology

Make a PhD enquiry


Public outreach & key achievements

  • Bianca Plouffe Stands out at Concours Étudiants-Chercheurs Étoiles

  • A precise target to tackle obesity: summary of the article co-signed by Michel Bouvier’s team in PNAS

  • Targeting a Hunger Hormone to Treat Obesity


Research students

PhD Title Non-canonical G protein signalling of US28 as a new target for glioblastoma
Country Northern Ireland
   

 


Discover More

  • Faculty of Medicine, Health and Life Sciences

  • School of Medicine, Dentistry and Biomedical Sciences

  • Wellcome-Wolfson Institute For Experimental Medicine 

Postgraduate research
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