Applicants interested in exploring both phenotypic as well as molecule association between changes in the eye and in the brain are encourage to apply.
Public outreach & key achievements
In our research, we are particularly interested in identifying the early changes underpinning the degeneration in the eye. Based on discussion with patients suffering from degeneration in the eye had identified that they believe that while their condition can only be improved by treating their condition, given that there are no cures in sight, prevention is very important to research that should be pursued. This is what we do.
Recently we obtained evidence that calcification is a major process that underpinned both the development and later the progression to age-related macular degeneration. This finding is relevant for both patients with age-related macular degeneration as well as Alzheimer's disease and particularly important for this with rare conditions like pseudoxanthoma elasticum. Now we are expanding our work and study changes in the eye in multiple sclerosis and Down syndrome. We are also exploring the potential to use stem cells and organoids for our work.
Currently, there are 2 PhD students in the lab. One is working on imaging and image analysis in multiple sclerosis and Alzheimer;s disease, the other is working on metabolic changes associated with degenration in the eye.
Alumni: Where are they now
Students from my laboratory are located on several countries from Asia to USA, working as postdoctoral fellows or in industry.
- Wellcome-Wolfson Institute For Experimental Medicine