My research seeks to understand the molecular mechanisms of inflammation, and how inflammasomes function in human health and disease. A particular focus has been small-molecule inhibitors of the NLRP3 inflammasome including landmark studies on MCC950. I have a record of innovative and translatable research that has been recognised internationally e.g. ICIS Regeneron New Investigator Award (2021). I am passionate about characterising inflammasome biology in human systems which will ultimately accelerate the development of new treatments for patients with inflammatory diseases.