The Dombrowski group is interested in the underlying immunological mechanisms that modulate tissue regeneration after sterile or infectious tissue damage.  Our goal is to identify novel therapeutic targets for incurable immune-mediated diseases such as Multiple Sclerosis.

Current PhD projects investigate the role of inflammasomes in tissue regeneration in the CNS in models of Multiple Sclerosis, inflammasome function in the lung after infectious tissue damage and the effect of e-cigarettes on inflammasome activation