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Find a PhD Supervisor

Professor Daniel Longley

School of Medicine, Dentistry and Biomedical Sciences

Professor Daniel Longley

School of Medicine, Dentistry and Biomedical Sciences

The focus of my research is drug resistance. Originally focused on resistance to standard-of-care chemotherapy in colorectal cancer, this work has broadened to include mechanisms of drug resistance in multiple cancers.

The mechanism of drug resistance that I have focused on most is cell death, particularly apoptosis. My most significant achievement in this area has been identification of the apoptosis-regulating protein FLIP as a key mediator of drug resistance, a biomarker of poor prognosis and potential therapeutic target for cancer. 

Contact info

  • View Academic Profile
  • d.longley@qub.ac.uk
  • +44 (0)28 9097 2636, +44 (0)28 9097 2647

Research Interests

Open to PhD applications in the field of

  • Cancer biology

  • Cell death

  • Drug resistance

Make a PhD enquiry


Public outreach & key achievements

  • Funding for Queen’s pancreatic cancer drug research 
  • Queen’s University Belfast and Domainex Win Late-Stage Award to Progress Novel Lung Cancer Drug Candidate into the Clinic
  • US-Ireland R&D: Successful Partnerships
  • FUNDING FOR QUEEN’S PANCREATIC CANCER DRUG RESEARCH IN COLLABORATION WITH FUSION ANTIBODIES
  • Fitting tribute to cancer expert Johnston as grant ensures legacy will live on

Research students

PhD Title Role of the oral commensal Fusobacterium Nucleatum in colorectal cancer.
Country England
   

 


Alumni: Where are they now

PhD Title Protein-protein interactions at the Death-Inducing Signalling Complex
Country England
Current Position  Post-doctoral researcher, QUB 
   

 

 

 


Postgraduate research
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Your postgraduate experience
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