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  • Research in the School of Medicine, Dentistry and Biomedical Sciences
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Find a PhD Supervisor

Dr Karim Dib

School of Medicine, Dentistry and Biomedical Sciences

Dr Karim Dib

School of Medicine, Dentistry and Biomedical Sciences

My research is focused on understanding the role of two G protein-coupled receptors in the regulation of anti-microbial functions of neutrophils. These receptors are: the histamine four receptor (H4R) and the proton-regulated receptor GPR68. During chronic lung inflammation, histamine level may raise in lung fluids and tissues. In parallel the pH drops due to the high metabolism of bacteria. Histamine and acidic conditions may impair neutrophil anti-microbial functions by controlling the activity of the H4R and GPR68, respectively.

Contact info

  • View Academic Profile
  • askmhls@qub.ac.uk
  • +44 (0)28 9097 2634, +44 (0)28 9097 2634

Research Interests

Open to PhD applications in the field of

  • To study the role of the histamine four receptor in the regulation of neutrophil phagocytosis
  • To study the role of acidic pH in the regulation of anti-microbial functions of neutrophils

Make a PhD enquiry


Current Research Opportunities

  • To investigate the role of histamine in the regulation of neutrophil phagocytosis

Public outreach & key achievements

  • We deliver outreach activities to the general public annually in our research Centre, the Centre for Experimental Medicine. 

Alumni: Where are they now

PhD Title The nitric oxide/cGMP pathway regulates neutrophil adhesion through activation of Rap GTPase
Country UK
Current Position  Senior Post-doctoral Fellow

 

 


Discover More

  • Faculty of Medicine, Health and Life Sciences

  • School of Medicine, Dentistry and Biomedical Sciences

  • Wellcome-Wolfson Institute For Experimental Medicine

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