Introduction
Healthcare research is rapidly growing with an increasing demand to identify the mechanisms of pathophysiology of disease and demonstrate proof-of-concept evidence of the efficacy and importance of new discoveries and treatments. Furthermore, there’s a need to test new technologies and therapies in clinical trials for better clinical care outcomes for patients. Subsequently, we offer a great opportunity for graduates who can undertake basic and clinical research and translate it into improved medical treatments for patients. This Master of Science programme in Biomedical and Clinical Research programme provides a strong learning environment for such graduates.
Who is the programme for
The MSc in Biomedical and Clinical Research is a research-intensive programme designed for students seeking to excel in academic research, clinical translation, clinical trials and the life sciences industry. This programme provides rigorous training in advanced research methodologies, critical analysis and innovative thinking – equipping graduates to tackle the most pressing biomedical and clinical challenges of the 21st century. With a string emphasis on interdisciplinary collaboration, the programme welcomes students from diverse backgrounds including biomedical sciences, medicine, dentistry, nursing, pharmacy and allied health specialities. Participants will engage in cutting-edge research projects, working alongside leading academics and clinicians to translate scientific discoveries into meaningful healthcare advancements. For medical and dental students, this MSc can be pursued as an intercalated degree, enhancing both research and clinical expertise. Additionally, the programme serves as a springboard for PhD , positioning graduates for leadership roles in biomedical innovation, clinical trials, and translational medicine.
Who we are
The MSc in Biomedical and Clinical Research is provided by the Wellcome-Wolfson Institute for Experimental Medicine (WWIEM). The Institute’s mission is the pursuit of scientific breakthroughs in understanding mechanisms of disease to improve health outcomes, and its vision is to be an international hub of excellence in innovation and discovery to cure disease and improve health. WWIEM is strategically placed to provide expertise for the Institute for Research Excellence in Advanced Clinical Healthcare (iREACH) centre, based at QUB. iREACH brings together the expertise of clinicians, life scientists and data scientists with experienced industry partners in a collaborative approach to clinical trial delivery.
About the MSc programme
In this programme students will undergo theoretical (didactic) and practical (project-based) training in biomedical and clinical research with an emphasis on clinical translation. One of the programmes objectives is to learn the research journey that spans between pathophysiology of the disease and translating that knowledge to develop novel diagnostic or therapeutic strategies to improve health. The modules focus on research related to the broad spectrum of expertise available in the WWIEM. The acquired skills range from a strong fundamental understanding of high-quality biomedical research, advanced experimental techniques to conduct research involving animal and in vitro disease models. The training also allows students to develop expertise in conducting clinical research to include observational studies as well as design and implementation of clinical trials, and the use of health informatics such as Electronic Health Records and how this information can be leveraged for translational bioinformatics research.
The programme is research-intensive and focuses on developing proficiency in experimental design and execution, regulatory and ethical aspects, data analysis and interpretation. Dedicated sessions will also emphasise training on scientific communication, presentation, grant writing, publishing, and use of social media in dissemination of findings.
The programme offers comprehensive research training with access to over 60 research groups and the state-of-the-art research facilities at the WWIEM. Research facilities include Central Technology Units for Imaging and Genomics which are leading the way in research excellence, in addition to the Clinical Trials Facility and the Northern Ireland Clinical Trials Unit.
Intercalated Medical and Dental Students
Completing an intercalated degree will boost your CV when applying for postgraduate training. Depending on the discipline, selection panels look for completion of an additional degree, or for publications or posters. An intercalated degree gives you the opportunity to improve your chances of future success.
Applicants are advised to apply as early as possible and ideally no later than 31st July 2026 for courses which commence in late September. In the event that any programme receives a high number of applications, the University reserves the right to close the application portal. Notifications to this effect will appear on the Applicant Management System [AMS] against the programme application page.
Please note a deposit will be required to guarantee a place on the course. Due to high demand, applications may not be considered if the course has reached its maximum class size and will be placed on a waiting list. Please see deposit terms and conditions for more details
The strong links between the (WWIEM) and the biotech or biopharmaceutical sectors provides a stimulating experimental and translational environment, while also expanding your career opportunities.
Biomedical and Clinical Research highlights
Professional Accreditations
You will have an opportunity to obtain a formally accredited certificate of training in good clinical practice (GCP) which is a necessary requirement prior to conducting clinical trial research. Students working with animal models of disease will also receive official training in animal handling, leading to a UK official animal handling personal license.
World Class Facilities
You will be taught and mentored within the WWIEM a purpose-built institute at the heart of the School of Medicine, Dentistry and Biomedical Sciences Campus, boasting state-of-the-art research facilities.
The programme offers comprehensive research training with access to over 60 research groups that are leading the way in research excellence and innovative healthcare.
Student Experience
A strength of this MSc incorporates transdisciplinary elements throughout the degree programme, which contribute to the delivery of innovative postgraduate education and research training. Central to this programme is a multi-disciplinary team of academic and clinical specialists, with expertise ranging from molecular disease phenotyping, functional genomics, infectious disease biology, vascular biology, genetic epidemiology, imaging, immunology, regenerative neuro-immunology, stem cell biology and exploitation, unique pre-clinical models of disease, respiratory diseases, developing and testing interventions in critical and emergency care, acute lung injury, patient-based investigations and clinical trials.
Student Testimonials
“I have thoroughly enjoyed my MSc. The taught component was very stimulating, and it was a privilege to learn from such experts in the field of immunology. I self-funded this MSc as a clinician to facilitate a career break, and I was fortunate to work with a supervisor who was encouraging in both my project and ongoing career goals. This course was well balanced, the module directors have been both supportive and expected a reasonable amount of self-directed learning. I was able to work remotely by performing a systematic review which was flexible to my needs and suited my aims.”
“I completed an undergraduate degree in Biomedical Science and decided to undertake the MSc. This MSc stood out to me as it offered students the choice of what area they wanted to study whether it be cardiovascular diseases or infection and immunity. Semester one was in-person lecture-based learning, which was great to experience again. Lectures were always extremely interesting and interactive with plenty of opportunities to ask questions. The assignments associated with each module, provided a great foundation for the research project. Semester two focused entirely on the research project, which you choose in semester one. I have been investigating the potential role of insulin in the regulation of neutrophil anti-microbial functions in the context of type 2 diabetics and infectious disease. Although the work was intense, I have really enjoyed my project in the lab. The guidance provided has been excellent and all supervisors/module co-ordinators have been extremely helpful throughout. Overall, I would say MSc is an extremely demanding and intense course but offers many rewarding experiences and opportunities. I have learnt so much throughout this course and have developed many invaluable skills that will translate into working life.”
The MSc in Biomedical and Clinical Research is a full-time postgraduate programme delivered over one year. The programme will primarily be of interest to students with undergraduate degrees in Biomedical Science or Healthcare Science related fields. Students will undertake 2 core taught modules, Core Research Skills and Clinical Translation (20 CATS each; total 40 CATS). Then, depending on their field of interest, students have a choice of optional modules on offer that include Advanced Research Skills (20 CATS), Delivering Clinical Trials from Protocol to Patient (20 CATS), Statistics in Public Health and Medical Research (10 CATS) and Health and Biomedical informatics and the Exposome (10 CATS). Students will also undertake an intensive research project (60 CATS) from a list of laboratory or non-laboratory projects that are offered and supervised by the academic faculty. Depending on the research project selected, students will be guided to select relevant optional modules that will suit laboratory, clinical or bioinformatic projects.
The MSc is awarded to students who successfully complete 120 CATS points (60 CATS taught modules, 60 CATS Research Project, and 60 CATS Dissertation).
A Postgraduate Diploma Exit qualification is available to those students who have successfully completed 120 CATS points (60 CATS, taught modules and 60 CATS research project).
A Postgraduate Certificate Exit qualification is available to those students who have successfully completed 60 CATS points of taught modules
Semester 1
Semester 1 comprises 3 months of intensive teaching, which includes the two core modules, and if selected, one optional module on advanced research skills or statistics.
SCM8145 Core Research Skills – CORE module, 20 CATS
In this module students learn the skills that embed excellence and rigour into the scientific approach to a research question. Active researchers teach students the core skills of designing and methodological approaches to testing a research hypothesis. Taught elements include database searches and approach to systematic reviews, basic principles of laboratory and clinical research design, regulatory requirements governing research, public involvement with science, data analysis, presentation, dissemination and communication of science. Students can undertake additional training in Good Clinical Practice, or training in animal handling procedures for a Home Office personal licence.
SCM8181 Clinical Translation – CORE module, 20 CATS
This module provides detailed theoretical and practical introduction about clinical translation. It focusses on state-of-the-art methods on research and clinical translation related to vascular, respiratory and infection/immunity related diseases. Current therapeutic approaches are also covered together with potential future strategies based on cutting edge translational research. The full spectrum of translational research is covered from animal and human models of disease through to the design and implementation of clinical trials.
Topics covered:
• Gene Therapy /CRISP/CAS9
• Drug development / repurposing
• Stem Cells / Reprogramming- Cell based Therapies
• Harnessing the immune system for therapeutics
• Pharmacokinetics / Pharmacodynamic studies
• Vaccine Development
• Developing new ways to tackle Antimicrobial Resistance
• Exploiting omics for therapeutics
• Harnessing the Microbiome
• High throughput drug screening
• Biomarker discovery
• Commercialisation
• Clinical Trials
SCM8180 Advanced Research Skills – OPTIONAL module, 20 CATS
This module provides a detailed theoretical and practical introduction to advanced research skills. It will provide a depth of knowledge of the research process and practical skills for the design and conduct of research studies, including data collection and analysis.
Topics covered:
• Preclinical Research Experimental Design.
• Advanced human cell culture, including stem cells.
• Advanced Imaging Training such as confocal microscopy.
• Single Cell RNA Sequencing
• Multi-dimensional parameter analysis of cell populations
• Bioinformatics
• Statistics
• Organoids / 3D Culture Systems
• 3D Printing
• Microfluidics
• Proteomics and Metabolomics
SCM8167 Statistics in Public Health and Medical Research – OPTIONAL module, 10 CATS
The module is delivered as lectures, and skills-based SPSS (a statistical package) computer laboratory practical's, and focuses on handling research data, performing statistical analysis and interpreting statistical output. It is delivered by a team of statisticians based in the Centre for Public Health.
Topics covered:
• Screening and presentation of data
• Sampling, estimation & confidence intervals
• Hypothesis testing - Proportions
• Hypothesis testing - Means and ANOVA
• Non-parametric methods
• Linear regression
• Logistic regression
• Survival analysis
• Systematic reviews and meta-analysis: methods
• Age-standardisation: methods•
Semester 2
SCM8148 Health and Biomedical informatics and the exposome – OPTIONAL module, 10 CATS
In this module students acquire the knowledge and skills to understand some of the most important concepts in health informatics and how these can be integrated with translational bioinformatics to facilitate the development of precision medicine approaches. This module also includes an introduction to the concept of the exposome and the contribution of biomedical informatics in exposome research. The module covers different aspects of health informatics including the basic structure of Electronic Health Records and how the information contained in these resources can be leveraged for translational bioinformatics research.
The module introduces some of the methods and tools (e.g. natural language processing (NLP) or coding tools) relevant for the extraction and reuse of clinical information for research purposes. Additionally, the course introduces the concept of the exposome, and its relevance for the development of precision medicine approaches. This will include a description of an emerging domain, exposome informatics, providing an insight about the main data types and sources relevant for exposome research. Finally, the course provides an integrative perspective and view of how all these elements work together to foster new comprehensive research approaches where biomedical informatics plays a key and central role
SCM8188 Delivering Clinical Trials – from protocol to patient – OPTIONAL module, 20 CATS
This module provides an overview of research processes and infrastructure that include:
• Setup of a clinical trial
• Collecting and managing data in trials
• Managing the conduct of a trial
• Patient screening, eligibility, consent, and randomisation
• Managing risk and reporting adverse events
• Basic laboratory procedures and documentation
On completion of this module the student will have gained an understanding of:
• Foundational knowledge of clinical research delivery, focused on clinical trials.
• Research delivery and regulatory infrastructure in Northern Ireland and the wider UK.
• The necessary skills required to facilitate the set-up and successful operational delivery of a clinical trial, including screening, eligibility, consent and randomisation.
• The processes involved in effective data collection, trial management and oversight.
• The ethical framework involved in clinical trials, and the steps needed to ensure the safety of trial participants and delivery of the research.
• The practical skills required to manage study documentation, data entry and laboratory sample processing.
SCM8146 Research Project – CORE module, 60 CATS
The Research Project is a major component of the programme, allowing the student to conduct high quality research during the MSc in Biomedical and Clinical Research. All projects will be performed in the WWIEM under the supervision of renowned academics with active research programmes in biomedical and clinical research and bioinformatics.
On completion of this module the successful student should be able to:
• Demonstrate a thorough understanding of the chosen subject area.
• Recognise the importance of planning and preparation required to undertake a research project.
• Apply foundational research skills to address a research question.
• Carry out a detailed research-based project.
• Demonstrate an understanding of the ethical issues associated with the subject area and research.
• Analyse data and synthesize research findings.
• Demonstrate the ability to collate and critically assess/interpret data
SCM8147 Dissertation – CORE module, 60 CATS
This Module comprises the write-up contribution to the overall research element of the Programme. It follows on from the Research Project. The Dissertation will present the student’s personal studies of the literature, a description of their study design and execution of their project, data presentation, analyses and interpretation, followed by critical discussion and conclusions. The Dissertation will be submitted electronically (15,000-20,000-words).
Learning opportunities associated with this course are outlined below:
At QUB, we deliver a high-quality learning environment that embeds intellectual curiosity, innovation and best practice in learning, teaching and student support to enable students to achieve their full academic potential. QUB has a long-established international reputation in experimental and translational medicine, achieved through the recognised metrics of high impact peer review publications, significant international research funding, the generation of exploitable novel intellectual property and the establishment of successful spin-out companies. Recognising the need for appropriately qualified scientific and healthcare graduates, this MSc programme offers a research intensive, student-oriented programme that will provide high quality candidates with the research rigour, the innovation culture and the leadership skills to be at the forefront of global biomedical and clinical revolution.
We do this by providing a range of learning experiences which enable our students to engage with subject experts, develop attributes and perspectives that will equip them for life and work that enhances their development as independent, lifelong learners.
Class times vary throughout morning and afternoon, and through a combination of course lectures, practical experiences and self-directed study to enhance employability.
Assessment
Assessment
Assessment is varied to enable students to demonstrate mastery of learning by a variety of methods. Assessment methods include a combination of individual and group oral presentations, written and social media assignments, completion of a logbook, examinations and a dissertation.
The information below is intended as an example only, featuring module details for the current year of study (2025/26). Modules are reviewed on an annual basis and may be subject to future changes – revised details will be published through Programme Specifications ahead of each academic year.
This Module provides detailed theoretical and practical introduction of Biomedical Science towards clinical translation. It focusses on state-of-the-art methods on the research and clinical translation related to vascular, cardiac respiratory, infection/immunity and autoimmune related diseases. Current therapeutic approaches are also covered together with potential future strategies based on cutting edge translational research. The full spectrum of translational Biomedical Science is covered from animal and human models of disease through to the design and implementation of clinical trials.
Topics to be covered:
Gene Therapy /CRISP/CAS9
Drug development / repurposing
Stem Cells / Reprogramming- Cell based Therapies
Harnessing the immune system for therapeutics
Pharmacokinetics / Pharmacodynamic studies
Vaccine Development
Developing new ways to tackle Antimicrobial Resistance
Exploiting omics for therapeutics
Harnessing the Microbiome
High throughput drug screening
Biomarker discovery
Commercialisation
Clinical Trials
Learning Outcomes
On completion of this module the successful student should be able to:
Demonstrate understanding on state-of-the-art methods on the research and clinical translation related to vascular, respiratory and infection/immunity related diseases.
Discuss vascular, respiratory, immunology and inflammation related disorders, and the current clinical needs and emerging research developments shaping future practice.
Critically evaluate the use of in vitro, in vivo and ex vivo models to support clinical translation.
Explain and critique the therapeutic approach to designing a new intervention (vaccine/therapeutic) or diagnostic tool.
Know and explain basic concepts behind clinical trials
Critically analyse relevant current scientific literature
Skills
On completion of this module successful students should be able to demonstrate:
Knowledge base – information gathering, literacy and management (preparation of assessments)
Cognitive abilities - Critical thinking and the synthesis of ideas (critically assess scientific literature to prepare “mock” clinical trial and oral presentations)
Creativity - Argument construction and intellectual insight (development of an idea and placement within the broader field of science and medicine)
Personal qualities – responsibility and self-motivation (private study)
Self-management – preparation of material and time management (throughout the course, preparation for each lecture, tutorial as well as completion of course work will be expected)
Professional and Career Development – networking, including interacting with other post-graduate students and research staff within the Wellcome Wolfson Institute of Experimental Medicine (WWIEM) Medicine and the Faculty of Medicine, Health and Life Sciences.
Communication and Dissemination – specialist communication methods, communication using social media (written and oral presentations)
Working with others – collegiality, collaboration, equality and diversity, influence and leadership (including integration into the department by attendance of journal club and seminar series.
Formulating and testing a research hypothesis
Performing robust literature searches
Critical appraisal of literature
Understanding systematic review and meta-analysis
Planning and writing a review of the literature
Scientific writing
- How to write a scientific report
- How to write a paper
- How to write an SOP
Data Management
Statistical analysis
Use of social media in science
Research integrity
Presentation skills
Research Dissemination and impact
Patient and public involvement (PPI) in research
Intellectual Property (IP) and commercialisation
Laboratory Research experimental design
Biomedical and Clinical Research Design and conduct
Learning Outcomes
On completion of this module successful students should be able to:
Demonstrate a clear ability to interrogate publicly available data bases and search engines to find existing evidence on a given subject
Demonstrate knowledge of rigorous research design
Demonstrate understanding of the ethical and regulatory principles behind animal and clinical research
Use social media platforms and other technology to engage the public in scientific and clinical research
Critically analyse relevant current scientific literature
Skills
On completion of this module the successful student should be able to demonstrate:
Knowledge base – information gathering, literacy and management (preparation of assessments)
Cognitive abilities - Critical thinking and the synthesis of ideas (critically assess scientific literature to prepare “mock” clinical trial and oral presentations)
Creativity - Argument construction and intellectual insight (development of an idea and placement within the broader field of science and medicine)
Personal qualities – responsibility and self-motivation (private study)
Self-management – preparation of material and time management (throughout the course, preparation for each lecture, tutorial as well as completion of course work will be expected)
Professional and Career Development – networking, including interacting with other post-graduate students and research staff within the Wellome Wolfson Institute for Experimental Medicine (WWIEM) and the Faculty of Medicine, Health and Life Sciences.
Communication and Dissemination – specialist communication methods, communication using social media (written and oral presentations)
Working with others – collegiality, collaboration, equality and diversity, influence and leadership (including integration into the department by attendance of journal club and seminar series.
This Module comprises the write-up contribution to the overall research element of the Programme. It follows on from the Research Project. The Dissertation will present the student’s personal studies of the literature, a description of their study design and execution of their project, data presentation, analyses and interpretation, followed by critical discussion and conclusions. The Dissertation will be submitted electronically (15,000-20,000 word thesis). The Dissertation will contain the following elements:
A 300 word abstract that concisely summarises the objectives, study design and main findings of the research.
Clearly defined aims and objectives of the study.
An in-depth, logically structured and up-to-date review of the research literature specifically pertaining to the student’s project, which should demonstrate an ability to efficiently summarise and critically analyse the major themes within the work. Original research papers, rather than reviews, should form the principle evidence base for the review.
A detailed and clearly presented description of the study design and techniques employed, including statistical analysis where appropriate.
A well-ordered and clearly presented description of the experimental results, illustrated by tables, diagrams, charts and micrographs where appropriate.
A discussion/conclusions section that offers a critical evaluation of the results and their significance in light of published literature on the topic and a rational justification of the conclusions drawn from the results.
A full bibliography of the literature cited in the text. Appropriate bibliography presentation formats.
Learning Outcomes
On completion of this module the successful student should be able to:
Demonstrate planning, and time management skills.
Apply critical thinking skills.
Report research findings in written form.
Demonstrate through understanding of the chosen subject area by reflection and critical evaluation.
Demonstrate a capacity to communicate research results clearly, comprehensively and convincingly in a dissertation-based format.
Develop the ability to effectively communicate knowledge in a scientific manner.
Provide recommendations based on research findings.
Skills
On completion of this module successful students should be able to demonstrate:
Knowledge base – information gathering, literacy and management (preparation of assessments)
Cognitive abilities - Critical thinking and the synthesis of ideas (critically assess scientific literature to prepare “mock” clinical trial and oral presentations)
Creativity - Argument construction and intellectual insight (development of an idea and placement within the broader field of science and medicine)
Personal qualities – responsibility and self-motivation (private study)
Self-management – preparation of material and time management (throughout the course, preparation for each lecture, tutorial as well as completion of course work will be expected)
Professional and Career Development – networking, including interacting with other post-graduate students and research staff within the Wellcome Wolfson Institute of Experimental Medicine (WWIEM) and the Faculty of Medicine, Health and Life Sciences.
Communication and Dissemination – specialist communication methods, communication using social media (written and oral presentations)
Working with others – collegiality, collaboration, equality and diversity, influence and leadership (including integration into the department by attendance of journal club and seminar series
The Research Project is a major component of the programme, allowing the student to conduct high quality research during the MSc in Biomedical and Clinical Research. All projects will be performed in the Wellcome Wolfson Institute of Experimental Medicine (WWIEM) under the supervision of renowned academics with active research programmes in biomedical and clinical research. The students will have access to state-of-the-art equipment and facilities.
In this module, students will join an established research team under the supervision of a WWIEM principal investigator. They will undertake a research project by devising and executing appropriate research designs
Learning Outcomes
On completion of this module the successful student should be able to:
Demonstrate a thorough understanding of the chosen subject area.
Recognise the importance of planning and preparation required to undertake a research project.
Apply foundational research skills to address a research question.
Carry out a detailed research-based project.
Demonstrate an understanding of the ethical issues associated with the subject area and research.
Analyse data and synthesize research findings.
Demonstrate the ability to collate and critically assess/interpret data.
Skills
On completion of this module successful students will be able to demonstrate:
Knowledge base – information gathering, literacy and management (preparation of assessments)
Cognitive abilities - Critical thinking and the synthesis of ideas (critically assess scientific literature to prepare “mock” clinical trial and oral presentations)
Creativity - Argument construction and intellectual insight (development of an idea and placement within the broader field of science and medicine)
Personal qualities – responsibility and self-motivation (private study)
Self-management – preparation of material and time management (throughout the course, preparation for each lecture, tutorial as well as completion of course work will be expected)
Professional and Career Development – networking, including interacting with other post-graduate students and research staff within the WWIEM and the Faculty of Medicine, Health and Life Sciences.
Communication and Dissemination – specialist communication methods, communication using social media (written and oral presentations)
Working with others – collegiality, collaboration, equality and diversity, influence and leadership (including integration into the department by attendance of journal club and seminar series.
This module provides a detailed theoretical and practical introduction to advanced research skills in Biomedical and Clinical Research. This will be a state-of-the-art module, providing in-depth knowledge of the research process, allowing students to acquire practical skills for the design and conduct of research studies, including data collection and analysis.
Topics that will be covered in this module include:
Preclinical in-vivo animal models, from zebra fish to transgenic mice.
Animal models from cardiovascular disease and ophthalmology research.
Techniques used to manipulate gene expression in animal cells (including CRISPR/Cas9).
Advanced imaging training.
Single cell sequencing and analysis.
Bioinformatics.
Flow cytometry (basic and advanced).
Organoids / 3D culture systems.
3D printing.
Microfluidics.
Proteomics and metabolomics.
Host-pathogen interactions (interactome).
Epigenetics.
Learning Outcomes
On completion of this module the successful student should be able to:
Demonstrate knowledge on advanced research skills
Design an experimental plan to investigate a research question.
Describe research methodology used to culture human cells, perform advanced microscopy and flow cytometry.
Explain single cell RNA sequencing data.
Describe uses of organoids/3D culture systems,, 3D printing, and microfluidics in research.
Critically evaluate current scientific literature in the field
Skills
The transferable skills (identified with the vitae research development framework) that the successful students should have developed upon completion of this module -:
Knowledge base – information seeking, information literacy and management (preparation of assessments)
Cognitive abilities - Critical thinking and the synthesis of ideas
Creativity - Argument construction and intellectual insight (development of an idea and placement with the broader field of science in Oral presentation preparation)
Personal qualities – responsibility and self-motivation (private study)
Self-management – preparation and prioritisation, time management (throughout course, preparation for each lecture, tutorial as well as completion of course work will be expected)
Communication and Dissemination – communication methods, communication media production (written, visual and oral)
Working with others – collegiality, collaboration, equality and diversity, influence and leadership
Health and Biomedical Informatics and the Exposome
Overview
At the end of this module students will have acquired the knowledge and skills to understand some of the most important concepts in health informatics and how these can be integrated with translational bioinformatics to facilitate the development of precision medicine approaches. This module also includes an introduction to the concept of the exposome and the contribution of biomedical informatics in exposome research.
The module will cover different aspects of health informatics ranging from the basic structure of Electronic Health Records (EHRs) and how the information contained in these resources can be leveraged for translational bioinformatics research.
It will introduce some of the methods and tools (e.g. natural language processing (NLP) or coding tools) relevant for the extraction and reuse of clinical information for research purposes.
The course will, as well, introduce the concept of the exposome, and its relevance for the development of precision medicine approaches. This will include a description of an emerging domain, exposome informatics, providing an insight about the main data types and sources relevant for exposome research.
Finally, the course will provide an integrative perspective and view of how all these elements work together to foster new comprehensive research approaches where biomedical informatics plays a key and central role.
Learning Outcomes
On completion of this module successful students will be able to:
Evaluate the basic components of health informatics;
Evaluate the main coding systems used in health informatics;
Explain the basic concepts associated with the exposome and how it is used in biomedical research;
Evaluate the main online resources containing exposome data and information;
Evaluate and apply different knowledge representation tools;
Integrate and analyse information from disparate data sources;
Combine and analyse data and information from clinical and multi-omics resources.
Skills
On successful completion of this module students will have gained or increased competence in:
Critical, analytical and creative thinking – increasing their knowledge base – identifying resources, gathering information, extracting important information;
Practical skills (analysis skills);
Problem solving abilities – increasing their cognitive abilities – critical thinking, synthesis of information and ideas;
Knowledge representation skills - increasing their ability to understand and use knowledge representation tools
Organisational and personal skills – including responsibility and self-motivation, self-confidence, personal integrity, setting own goals and time management;
Time management skills;
Communication and dissemination – speaking effectively, writing concisely, listening attentively, persuading
Working with others – collaboration, awareness of equality and diversity, leadership skills.
The module is delivered as lectures, and skills-based SPSS (a statistical package) computer laboratory practicals, and focuses on handling research data, performing statistical analysis and interpreting statistical output. It is delivered by a team of statisticians based in CPH.
Core content includes:
Screening and presentation of data
Sampling, estimation & confidence intervals
Hypothesis testing - Proportions
Hypothesis testing - Means and ANOVA
Non-parametric methods
Linear regression
Logistic regression
Survival analysis
Systematic reviews and meta-analysis: methods
Age-standardisation: methods
Learning Outcomes
On successful completion learners should be able to:
Select appropriate statistical methods for summarising data, for testing statistical hypotheses, for describing relationships and for assessing confounding.
Perform statistical analyses using a computer package and interpret the output from such analyses.
Appraise the assumptions required for these statistical methods and their limitations.
Define the important role played by statistics in science and medicine
Skills
Subject-specific Skills :
Statistical approach and perspective to medical and public health research; surveillance and assessment of the population's health and well-being; planning, analysing, and assessing the evidence of effectiveness of medical, health and healthcare interventions.
Cognitive Skills:
Critical, analytical and creative thinking; systematic approach to problem-solving; systematic approach to assessment or evaluation.
Transferable Skills:
Self-directed learning; study skills; research skills; written and verbal communication skills; information technology skills; time management; numerical and data handling skills; general IT skills; experience in the use of Statistical Software (SPSS)
Delivering Clinical Trials - from Protocol to Patient
Overview
Overview of research processes and infrastructure.
Setup of a clinical trial
Collecting and managing data in trials
Managing the conduct of a trial
Patient screening, eligibility, consent, and randomisation
Managing risk and reporting adverse events
Basic laboratory procedures and documentation
Learning Outcomes
To provide participants with foundational knowledge of clinical research delivery, focused on clinical trials.
To help participants understand research delivery and regulatory infrastructure in Northern Ireland and the wider UK.
To provide participants with necessary skills required to facilitate the set-up and successful operational delivery of a clinical trial, including screening, eligibility, consent and randomisation.
To understand the processes involved in effective data collection, trial management and oversight.
To understand the ethical framework involved in clinical trials, and the steps needed to ensure the safety of trial participants and delivery of the research.
To foster the acquisition of practical skills required to manage study documentation, data entry and laboratory sample processing.
Skills
On completion of the course, the student should be able to:
Set up a clinical trial, based on a trial protocol
Navigate key steps in trial planning phase including risk assessment, sponsorship, protocol development, contracts and funding/finance agreements
Navigate regulatory approvals and governance processes relevant to clinical trials.
Undertake data management and to prepare an effective case report form.
Submit research amendments
Undertake screening and support eligibility assessment for clinical trials.
Describe the consent process and key principles
Work with patient and public representatives to design and deliver clinical trials.
Undertake basic risk assessment
Report adverse events appropriately.
Accurately record biological samples in a sample tracking log.
Safely undertake basic laboratory procedures such as pipetting, centrifugation, and freezing.
Normally a minimum of a 2.1 Honours degree or equivalent qualification acceptable to the University in a biological sciences-related subject. Evidence of equivalent professional qualifications (MBBS, BDS or BVSc) or experience will be considered on an individual basis.
Intercalating Medical and Dental Applicants:
i) QUB:
Intercalating medical and dental students within QUB will be considered if:
a) QUB 3rd year students – must pass all 3rd year modules at first attempt achieving an overall profile of 2.1 equivalent *.
b) QUB 4th year students – must pass all 3rd year modules at first attempt achieiving an overall profile of 2.1 equivalent * and also pass all 4th year modules at first attempt.
c) have permission to intercalate from either the Director of Medical Education or Dentistry as appropriate.
ii) External:
An external medical or dental student wishing to intercalate will be considered if:
a) they have successfully completed all assessments at first attempt for the year in which they are applying.
b) they have achieved at least an overall Upper Second Class Honours degree standard as determined by their University.
c) they have have permission to intercalate from their Medical or Dental School, as appropriate.
iii) International:
a) Applicants who are currently studying an overseas Medical (e.g. MBBS or MBChB) or Dental degree at a recognised institution acceptable to the University, may apply.
b) Applicants must have passed all assessments at first attempt for the year in which they are applying, normally 3rd year for those completing a 5 year programme or 4th year for those completing a 6 year programme.
c) Applicants may be required to provide details of the medical or dental curriculum they are studying in order to confirm compatibility.
d) Have permission to intercalate from their Medical or Dental School, as appropriate.
Applicants are advised to apply as early as possible and ideally not later than 31st July 2026. In the event that any programme receives a high number of applications, the University reserves the right to close the application portal prior to the deadline stated on course finder. Notifications to this effect will appear on the application portal against the programme application page.
Please note: A deposit will be required to secure a place on this course.
International Students
Our country/region pages include information on entry requirements, tuition fees, scholarships, student profiles, upcoming events and contacts for your country/region. Use the dropdown list below for specific information for your country/region.
English Language Requirements
An IELTS Academic test score of 6.5 overall with a minimum of 6.0 in each of the four elements or an equivalent qualification acceptable to the University (taken within the last 2 years). IELTS test result/qualification must be submitted by 30 June 2025.
International students wishing to apply to Queen's University Belfast (and for whom English is not their first language), must be able to demonstrate their proficiency in English in order to benefit fully from their course of study or research. Non-EEA nationals must also satisfy UK Visas and Immigration (UKVI) immigration requirements for English language for visa purposes.
If you need to improve your English language skills before you enter this degree programme, Queen's University Belfast International Study Centre offers a range of English language courses. These intensive and flexible courses are designed to improve your English ability for admission to this degree.
Academic English: an intensive English language and study skills course for successful university study at degree level
Pre-sessional English: a short intensive academic English course for students starting a degree programme at Queen's University Belfast and who need to improve their English.
The programme is designed for students wishing to pursue a career in biomedical and clinical research, whether it is in academia, clinical practice, industry or government. The programme will also provide an excellent platform for progression to PhD programmes either in Queen’s or worldwide.
Employment after the Course
Upon completing the course, students with a biomedical background often secure positions in industry or within the health service, leveraging their skills in healthcare informatics or clinical research. Others may pursue a PhD and embark on an academic career.
Alumni Success
In five years, I envision myself thriving in a dynamic role within the healthcare sector, leveraging my expertise in industry, healthcare informatics or clinical research. Whether driving innovation in a leadership position, contributing to groundbreaking health solutions, or advancing research and mentoring future professionals in an academic setting, my goal is to be at the forefront of transformative advancements in healthcare.
Prizes and Awards
The top ranked candidate in the year will receive a Book Prize and Certificate of Merit.
Graduate Plus/Future Ready Award for extra-curricular skills
In addition to your degree programme, at Queen's you can have the opportunity to gain wider life, academic and employability skills. For example, placements, voluntary work, clubs, societies, sports and lots more. So not only do you graduate with a degree recognised from a world leading university, you'll have practical national and international experience plus a wider exposure to life overall. We call this Graduate Plus/Future Ready Award. It's what makes studying at Queen's University Belfast special.
1EU citizens in the EU Settlement Scheme, with settled status, will be charged the NI or GB tuition fee based on where they are ordinarily resident. Students who are ROI nationals resident in GB will be charged the GB fee.
2 EU students who are ROI nationals resident in ROI are eligible for NI tuition fees.
3 EU Other students (excludes Republic of Ireland nationals living in GB, NI or ROI) are charged tuition fees in line with international fees.
All tuition fees quoted relate to a single year of study unless stated otherwise. Tuition fees will be subject to an annual inflationary increase, unless explicitly stated otherwise.
Students have the option to hire a locker, at a cost of £5 per student, per year.
Terms and Conditions for Postgraduate applications:
1.1 Due to high demand, there is a deadline for applications.
1.2 You will be required to pay a deposit to secure your place on the course. The current mandatory tuition fee deposit payment is:
• £400 for Domestic (NI/ROI/GB) students
• £1000 International (Non- EU & EU except ROI).
1.3 This condition of offer is in addition to any academic or English language requirements.
Read the full terms and conditions at the link below:
The MacQuitty Experimental Medicine Scholarship
The MacQuitty Experimental Medicine Scholarship will award £17,600 to pay full postgraduate fees for one year to one student who is a permanent resident in Northern Ireland and who has been accepted onto the Queen’s School of Medicine, Dentistry & Biomedical Sciences MSc Experimental Medicine. The remaining sum will be given as an additional bursary to support accommodation fees, study materials, food, living and travel expenses.
Further information on this scholarships, eligibility criteria, application process etc will be circulated to all students who have been accepted onto the MSc Experimental Medicine in January 2025. The closing date will be Monday 24 March. https://www.qub.ac.uk/Study/postgraduate/tuition-fees/deposit-refunds-policy/
MacQuitty MSc Experimental Medicine Scholarship
The MacQuitty Experimental Medicine Scholarship will award £17,600 to pay full postgraduate fees for one year to one student who is a permanent resident in Northern Ireland and who has been accepted onto the Queen’s School of Medicine, Dentistry & Biomedical Sciences MSc Experimental Medicine.
The remaining sum will be given as an additional bursary to support accommodation fees, study materials, food, living and travel expenses. Please refer to the advertisement in the link below for further information. An application form should be submitted to the Postgraduate Professional Development office by email to the pgoffice.smdb@qub.ac.uk no later than Wednesday 8 May 2024, 10am. Link to MacQuitty Scholarship Advertisement
All Students
Depending on the programme of study, there may be extra costs which are not covered by tuition fees, which students will need to consider when planning their studies.
Students can borrow books and access online learning resources from any Queen's library. If students wish to purchase recommended texts, rather than borrow them from the University Library, prices per text can range from £30 to £100. Students should also budget between £30 to £75 per year for photocopying, memory sticks and printing charges.
Students undertaking a period of work placement or study abroad, as either a compulsory or optional part of their programme, should be aware that they will have to fund additional travel and living costs.
If a programme includes a major project or dissertation, there may be costs associated with transport, accommodation and/or materials. The amount will depend on the project chosen. There may also be additional costs for printing and binding.
Students may wish to consider purchasing an electronic device; costs will vary depending on the specification of the model chosen.
There are also additional charges for graduation ceremonies, examination resits and library fines.
How do I fund my study?
The Department for the Economy will provide a tuition fee loan of up to £6,500 per NI / EU student for postgraduate study. Tuition fee loan information.
A postgraduate loans system in the UK offers government-backed student loans of up to £11,836 for taught and research Masters courses in all subject areas (excluding Initial Teacher Education/PGCE, where undergraduate student finance is available). Criteria, eligibility, repayment and application information are available on the UK government website.
