Analyze, interpret and appraise experimental data

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Essays

Adopt various experimental approaches and combine information from different sources to develop an experimental plan

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Presentations

Evaluate ethical issues in human and animal research

Teaching/Learning Methods and Strategies

Masterclasses, Journal Clubs, Guided Self-Directed Learning and Small Group Learning

Methods of Assessment

Presentation, Written assignment

Critically evaluate scientific literature

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Written Assignments

Apply analytical, numerical and creative thinking skills

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Presentations

Demonstrate effective oral and written communication skills, including presenting scientific information

Teaching/Learning Methods and Strategies

Masterclasses

Methods of Assessment

Presentations, Written assignments

Develop own knowledge and skills and contribute to the development of others, through active participation in teamwork and group learning opportunities

Teaching/Learning Methods and Strategies

Journal Clubs, Small Group Learning

Methods of Assessment

Presentations

Use information technology with particular emphasis on the recording of information and data retrieval

Teaching/Learning Methods and Strategies

Guided Self Directed Learning, Small Group Learning, Practicals

Methods of Assessment

Written assignments

Apply scientific research principles and audit

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Written assignments

Enhance Professional and Career Development portfolio

Teaching/Learning Methods and Strategies

Seminars, Masterclasses

Methods of Assessment

Written assignment

Understand genomic alterations that lead to cellular phenotype changes in human disease

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Oral Presentations

Outline the principles of clinical trial design and indicate how translational studies can be incorporated into clinical trials

Teaching/Learning Methods and Strategies

Tutorials

Methods of Assessment

Written assignments

Critically evaluate current scientific literature.

Teaching/Learning Methods and Strategies

Journal Clubs

Methods of Assessment

Presentations

Discuss research ethics in relation to studies in humans and animals and correctly apply established principles and legislation to these areas of research

Teaching/Learning Methods and Strategies

Guided Self Directed Learning

Methods of Assessment

Presentations

Critically analyse and discuss principles of translational medicine and how they can be applied in translational/clinical arenas

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Written assignments

Demonstrate the ability to write a research report, indicating progress and future plans/directions

Teaching/Learning Methods and Strategies

Guided Self Directed Learning

Methods of Assessment

Written assignments

Critically appraise a scientific paper

Teaching/Learning Methods and Strategies

Lectures, Tutorials

Methods of Assessment

Written assignments, oral presentations

Discuss the factors that contribute to a high quality clinical trial.

Teaching/Learning Methods and Strategies

Lectures, Tutorials

Methods of Assessment

Presentation

Depending on their subject specialty, the successful student will also be able to demonstrate the skill sets as indicated below. Throughout the different themes, emphasis will be placed on critical thinking using tutorials where the students will critique published scientific research.

Teaching/Learning Methods and Strategies

not applicable

Methods of Assessment

not applicable

Advanced Research Skills in Experimental Medicine

This module provides a detailed theoretical and practical introduction to advanced research skills in Experimental Medicine. This will be a state of the art Module. It will provide a depth of knowledge of the research process and practical skills for the design and conduct of research studies, including data collection and analysis.
Topics, which will be covered in this module include:
•Preclinical Research Experimental Design.
•Advanced human cell culture, including stem cells.
•Advanced Imaging Training such as confocal microscopy.
•Single Cell RNA Sequencing
•Multi-dimensional parameter analysis of cell populations
•Bioinformatics
•Statistics
•Organoids / 3D Culture Systems
•3D Printing
•Microfluidics
•Proteomics and Metabolomics

Teaching/Learning Methods and Strategies

Lectures, Tutorials, Masterclasses and Seminars

Methods of Assessment

Presentation/Written assignments

Explain the principles underpinning advanced research skills
Design an experimental plan to investigate a research question.
Describe research methodology used to culture human cells, perform advanced microscopy and flow cytometry.
Explain single cell RNA sequencing data.
Describe uses of organoids/3D culture systems, 3D printing, and microfluidics in research.
Critically evaluate current scientific literature in the field

Teaching/Learning Methods and Strategies

Lectures, Tutorials, Masterclasses and Seminars

Methods of Assessment

Presentation/Written assignments

Experimental Medicine towards Clinical Translation:

This module provides a detailed theoretical and practical introduction in Experimental Medicine towards clinical translation. It focusses on state-of-the-art methods in the research and clinical translation related to vascular, respiratory and infection/immunity related diseases. Current therapeutic approaches are also covered together with potential future strategies based on cutting edge translational research. The full spectrum of translational experimental medicine is covered from animal and human models of disease through to the design and implementation of clinical trials.
Topics to be covered include:
Gene Therapy /CRISP/CAS9
Drug development / repurposing
Stem Cells / Reprogramming- Cell based Therapies
Harnessing the immune system for therapeutics
Pharmacokinetics / Pharmacodynamic studies
Vaccine Development
Developing new ways to tackle Antimicrobial Resistance
Exploiting omics for therapeutics
Harnessing the Microbiome
High throughput drug screening
Biomarker discovery
Commercialisation
Clinical Trials

Teaching/Learning Methods and Strategies

Lectures, Tutorials, Masterclasses and Seminars

Methods of Assessment

Presentation/Written assignments

Recognise and utilise state-of-the-art methods on the research and clinical translation related to vascular, respiratory and infection/immunity related diseases.
Discuss vascular, respiratory, immunology and inflammation related disorders, and the current clinical needs and emerging research developments shaping future practice.
Critically evaluate the use of in vitro, in vivo and ex vivo models to support clinical translation.
Explain and critique the therapeutic approach to designing a new intervention (vaccine/therapeutic) or diagnostic tool.
Explain basic concepts behind clinical trials
Critically analyse relevant current scientific literature

Teaching/Learning Methods and Strategies

Lectures, Tutorials, Masterclasses and Seminars

Methods of Assessment

Presentation/Written assignments

Critically analyse experimental approaches to address research hypotheses

Teaching/Learning Methods and Strategies

Lectures

Methods of Assessment

Written Assignments

Explain techniques that will underpin the experimental design of their Research Project

Teaching/Learning Methods and Strategies

Seminars

Methods of Assessment

Oral Presentations