Publications
Publications:
2025
- Saha C, et al. Development of a nano-vaccine for high-grade serous ovarian cancer. Biomater ci. doi: 10.1039/d4bm01696c.
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Li M, et al. Bimodal Dissolving Microneedles with Nanoparticle Coating and Encapsulation for Extended Dual-Drug Delivery. Small. doi: 10.1002/smll.202502904.
- Chambers SEJ, et al. Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity. Angiogenesis. doi: 10.1007/s10456-025-09982-8.
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Szczepan M, et al. Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.66.3.41.
- Hahn H, et al. Endosomal chemokine receptor signalosomes regulate central mechanisms underlying cell migration. Elife. doi: 10.7554/eLife.99373.
- Parau G, et al. Clinical isolates of antimicrobial resistant Enterobacter species can persist in human macrophages without replication and overt cellular cytotoxicity. J Infect Dis. doi: 10.1093/infdis/jiaf099.
- Alotaibi H, Hatahet T, Al-Jamal WT. Understanding the formulation parameters for engineering indocyanine green J-aggregate lipid nanocapsules and solid lipid nanoparticles as promising photothermal agents. Eur J Pharm Sci. doi: 10.1016/j.ejps.2025.107034.
- Pentlavalli S, et al. D-peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention. J Control Release. doi: 10.1016/j.jconrel.2024.12.052.
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Armstrong R, et al. Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development. PLoS Pathog. doi: 10.1371/journal.ppat.1012562.
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Dedeloudi A, et al. Biopolymeric 3D printed scaffolds as a versatile tissue engineering treatment for congenital diaphragmatic hernia. Int J Pharm. doi: 10.1016/j.ijpharm.2025.125313.
- Gade S, Vora LK, Thakur RRS. Design and characterization of hollow microneedles for localized intrascleral drug delivery of ocular formulations. Methods. doi: 10.1016/j.ymeth.2024.12.004.
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Paris JL, et al. Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform. Int J Pharm. doi: 10.1016/j.ijpharm.2024.125064.
- Martín-Vicente P, et al. Mechanical Stretch Induces Senescence of Lung Epithelial Cells and Drives Fibroblast Activation by Paracrine Mechanisms. Am J Respir Cell Mol Biol. doi: 10.1165/rcmb.2023-0449OC.
- Al-Jamal WT, et al. Biodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: Formulation, in vitro toxicity and in vivo clearance. Int J Pharm. doi: 10.1016/j.ijpharm.2024.124963.
2024
- Ramos H, et al. Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/- rat model. J Neuroinflammation. doi: 10.1186/s12974-024-03283-5.
- Brown R, et al. SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease. Front Immunol. doi: 10.3389/fimmu.2024.1433642.
- Naderi-Meshkin H, et al. Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids. Stem Cells. doi: 10.1093/stmcls/sxae043.
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Pathak V, et al. Modulation of diabetes-related retinal pathophysiology by PTX3. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.2320034121.
- Faizi HS, Nasiri MI, Wu Y, Mishra D, Donnelly RF, Minhas MU, Vora LK, Singh Thakur RR. Deferasirox nanosuspension loaded dissolving microneedles for ocular drug delivery. Int J Pharm. doi: 10.1016/j.ijpharm.2024.124614.
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Alsa'd AA, et al. Optimising intracellular delivery of antibiotic loaded PLGA nanoparticles to macrophages. Int J Pharm. doi: 10.1016/j.ijpharm.2024.124567.
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Liu X, et al. Non-linear responses via agglomeration and aggregation of gold nanoparticles for surface-enhanced Raman spectroscopy (SERS) coupled with chemometric analysis for chlorpyrifos detection. Food Chem. doi: 10.1016/j.foodchem.2024.139944.
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Carvalho AM, et al. Development of CD33-Targeted Dual Drug-Loaded Nanoparticles for the Treatment of Pediatric Acute Myeloid Leukemia. Biomacromolecules. doi: 10.1021/acs.biomac.4c00672.
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Glass K, et al. Development and Characterization of a Peptide-Bisphosphonate Nanoparticle for the Treatment of Breast Cancer. Mol Pharm. doi: 10.1021/acs.molpharmaceut.4c00299.
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Saha S, et al. Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor. Cell. doi: 10.1016/j.cell.2024.07.005.
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Li Y, Wang J, et al. Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch. J Control Release. doi: 10.1016/j.jconrel.2024.06.039.
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McMillan HP, et al. Immunological isolation and characterization of neuronal progenitors from human dental pulp: A laboratory-based investigation. Int Endod J. doi: 10.1111/iej.14077.
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Miles CM, et al. Unravelling the interactions between small molecules and liposomal bilayers via molecular dynamics and thermodynamic modelling. Int J Pharm. doi: 10.1016/j.ijpharm.2024.124367.
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Dunne VL, et al. PTEN Depletion Increases Radiosensitivity in Response to Ataxia Telangiectasia-Related-3 (ATR) Inhibition in Non-Small Cell Lung Cancer (NSCLC). Int J Mol Sci. doi: 10.3390/ijms25147817.
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Sushentsev N, et al. Metabolic imaging across scales reveals distinct prostate cancer phenotypes. Nat Commun. doi: 10.1038/s41467-024-50362-5.
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Dupont M, et al. The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic Acids Res. doi: 10.1093/nar/gkae291.
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Risseeuw, S., et al. (2024). Bruch's membrane calcification in pseudoxanthoma elasticum: comparing histopathology and clinical imaging. Ophthalmology Science. doi.org/10.1016/j.xops.2023.100416
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Li H, Anjani QK, et al. Design of a Novel Delivery Efficiency Feedback System for Biphasic Dissolving Microarray Patches Based on Poly(Lactic Acid) and Moisture-Indicating Silica. Adv Healthc Mater. doi: 10.1002/adhm.202304082.
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Qian K, Stella L, Liu F, Jones DS, Andrews GP, Tian Y. Kinetic and Thermodynamic Interplay of Polymer-Mediated Liquid-Liquid Phase Separation for Poorly Water-Soluble Drugs. Mol Pharm. doi: 10.1021/acs.molpharmaceut.4c00033.
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Fuster MG, Wang J, Fandiño O, Víllora G, Paredes AJ. Folic Acid-Decorated Nanocrystals as Highly Loaded Trojan Horses to Target Cancer Cells. Mol Pharm. doi: 10.1021/acs.molpharmaceut.3c01186.
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McCusker P, et al. Neoblast-like stem cells of Fasciola hepatica. PLoS Pathog . doi.org/10.1371/journal.ppat.1011903
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Bonazza S, et al. Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking. PLoS Pathog. doi.org/10.1371/journal.ppat.1012231
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McMillan HP, et al. Immunological isolation and characterization of neuronal progenitors from human dental pulp: A laboratory-based investigation. Int Endod J. doi: 10.1111/iej.14077.
- Llorián-Salvador M, et al. Regulatory T cells limit age-associated retinal inflammation and neurodegeneration. Mol Neurodegener. Doi: 10.1186/s13024-024-00724-w.
- Demartis S, et al. Improved pharmacokinetic and lymphatic uptake of Rose Bengal after transfersome intradermal deposition using hollow microneedles. J Control Release. doi: 10.1016/j.jconrel.2024.03.048.
- Ouyang X, et al. House dust mite allergens induce Ca2+ signalling and alarmin responses in asthma airway epithelial cells. Biochim Biophys Acta Mol Basis Dis. doi: 10.1016/j.bbadis.2024.167079.
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Dallal Bashi YH, et al. Inhaled dry powder liposomal azithromycin for treatment of chronic lower respiratory tract infection. Int J Pharm. doi: 10.1016/j.ijpharm.2024.123841.
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Wilson JJ, et al. Synthesis and characterisation of a nucleotide based pro-drug formulated with a peptide into a nano-chemotherapy for colorectal cancer. J Control Release. doi: 10.1016/j.jconrel.2024.03.036.
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Li H, Anjani QK, et al. Design of a Novel Delivery Efficiency Feedback System for Biphasic Dissolving Microarray Patches Based on Poly(Lactic Acid) and Moisture-Indicating Silica. Adv Healthc Mater. doi: 10.1002/adhm.202304082.
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de la Fuente AG, et al. Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination. Nat Commun. doi: 10.1038/s41467-024-45742-w.
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Roussel S, Udabe J, Bin Sabri A, Calderón M, Donnelly R. Leveraging novel innovative thermos responsive polymers in microneedles for targeted intradermal deposition. Int J Pharm. doi: 10.1016/j.ijpharm.2024.123847.
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Holloway J,et al. The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis. Cell Death Dis. doi: 10.1038/s41419-023-06417-4.
- Anderson A, et al. Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status. Nat Commun. doi: 10.1038/s41467-024-45387-9.
- Smith MR, Naeli P, Jafarnejad SM, Costa G. The scaffolding protein AKAP12 regulates mRNA localization and translation. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.2320609121.
- Dunne OM, et al. TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells. Respir Res. doi: 10.1186/s12931-024-02807-0.
2023
- Al Natour B, et al. Regulation of caries-induced pulp inflammation by NLRP3 inflammasome: A laboratory-based investigation. Int Endod J. doi: 10.1111/iej.13855.
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McKerr, N., Mohd-Sarip, A., Dorrian, H. et al. CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation. Sci Rep https://doi.org/10.1038/s41598-023-28693-y
- Risseeuw S, et al.Bruch's Membrane Calcification in Pseudoxanthoma Elasticum: Comparing Histopathology and Clinical Imaging. Ophthalmol Sci. doi: 10.1016/j.xops.2023.100416.
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Zhang C, et al. Curcumin nanocrystals-in-nanofibres as a promising platform for the management of periodontal disease. Int J Pharm. doi: 10.1016/j.ijpharm.2023.123585.
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Sadowska JM, et al.. Development of miR-26a-activated scaffold to promote healing of critical-sized bone defects through angiogenic and osteogenic mechanisms. Biomaterials. doi: 10.1016/j.biomaterials.2023.122398.
- Tabaei SR, et al. Recapitulating the Lateral Organization of Membrane Receptors at the Nanoscale. ACS Nano. doi: 10.1021/acsnano.3c00683.
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Lou-Franco J, et al. Smartphone-based immunochemical sensor exploiting peroxidase-like activity of ligand-capped gold nanostars: A proof-of-concept detection of Mycobacterium bovis. Biosens Bioelectron. doi: 10.1016/j.bios.2022.114857.
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Bombin ADJ, et al. Delivery of a peptide/microRNA blend via electrospun antimicrobial nanofibres for wound repair. Acta Biomater. doi: 10.1016/j.actbio.2022.10.059.
- Zhang, Y., Ye, Z., Li, C. et al. General approach to surface-accessible plasmonic Pickering emulsions for SERS sensing and interfacial catalysis. Nat Commun https://doi.org/10.1038/s41467-023-37001-1
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Álvarez-Barrios, A., et al.2023. Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium. Frontiers in Nutrition. https://doi.org/10.3389/fnut.2023.1124987
2022
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Bianchi MB, et al. Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues. Mater Today Bio. doi: 10.1016/j.mtbio.2022.100471.
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Abd-El-Azim, H., et al. Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer. Journal of controlled release : official journal of the Controlled Release Society, doi.org/10.1016/j.jconrel.2022.06.027
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Broadbent, L., et al. An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells. PLoS ONE, doi.org/10.1371/journal.pone.0266412
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Dumigan A, et al. In vivo single-cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection. EMBO Mol Med. doi:10.15252/emmm.202216888.
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Kurzawa-Akanbi M, et al. Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina. J Extracell Vesicles. doi: 10.1002/jev2.12295.
- Tabel, M., et al. Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration. Journal of Neuroinflammation, 19, [229].
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Jacobs E, et al. Design and scale-up of amorphous drug nanoparticles production via a one-step anhydrous continuous process. Int J Pharm. doi:10.1016/j.ijpharm.2022.122304
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Robb E, et al. Transcriptomic analysis supports a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles. PLoS Negl Trop Dis. doi: 10.1371/journal.pntd.0010854.
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Demartis S, et al. Trilayer dissolving polymeric microneedle array loading Rose Bengal transfersomes as a novel adjuvant in early-stage cutaneous melanoma management. Int J Pharm. doi: 10.1016/j.ijpharm.2022.122217.
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Harkin, K., et al. Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 Pathway. Biomedicines, doi.org/10.3390/biomedicines10020311
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O'Hare, M., et al. Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats. JCI insight, 7(18). doi.org/10.1172/jci.insight.155128
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Tsolaki E, et al. Nuclear and cellular, micro and nano calcification in Alzheimer's disease patients and correlation to phosphorylated Tau. Acta Biomater. doi: 10.1016/j.actbio.2022.03.003.
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Matute-Blanch C, et al. Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non-cell-autonomous neuronal damage. Clin Transl Med. doi: 10.1002/ctm2.837.
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Jia Lin, et al. USP17 is required for peripheral trafficking of lysosomes. EMBO reports. e51932https://doi.org/10.15252/embr.202051932
- Nasiri, M.I. et al. Nanoemulsion-based dissolving microneedle arrays for enhanced intradermal and transdermal delivery. Drug Deliv. and Transl. Res. doi.org/10.1007/s13346-021-01107-0
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Wu, Y., et al. Nanosuspension-loaded dissolving bilayer microneedles for hydrophobic drug delivery to the posterior segment of the eye. Biomaterials Advances, doi.org/10.1016/j.bioadv.2022.212767
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Wu Y, et al. Long-acting nanoparticle-loaded bilayer microneedles for protein delivery to the posterior segment of the eye. Eur J Pharm Biopharm. doi: 10.1016/j.ejpb.2021.05.022.
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Albargothy, M. J., et al. Investigation of heterocellular features of the mouse retinal neurovascular unit by 3D electron microscopy. Journal of Anatomy. doi.org/10.1111/joa.13721
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Albadr AA, et al. Rapidly dissolving microneedle patch of amphotericin B for intracorneal fungal infections. Drug Deliv Transl Res. doi: 10.1007/s13346-021-01032-2.
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Pereira S, et al. Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy. Acta Biomater. doi: 10.1016/j.actbio.2021.12.019.
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Llorián-Salvador, et al. Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells. Journal of Neuroinflammation. doi.org/10.1186/s12974-022-02546-3
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Bertelli PM, et al. Long term high glucose exposure induces premature senescence in retinal endothelial cells. Frontiers in Physiology, doi.org/10.3389/fphys.2022.929118
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Su Y, et al. Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis. Thorax. doi.org/10.1136/thoraxjnl-2021-218194
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Pereira S. et al. Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy. Acta biomaterialia, doi.org/10.1016/j.actbio.2021.12.019
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Reina, G., et al. Design of a graphene oxide-BODIPY conjugate for glutathione depletion and photodynamic therapy. 2D Materials. doi.org/10.1088/2053-1583/ac4572
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Osbourn M., et al. Secretory leucoprotease inhibitor (SLPI) promotes survival during acute pseudomonas aeruginosa infection by suppression of inflammation rather than microbial killing. Biomolecules. doi.org/10.3390/biom12121728
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Sahu, S. K., et al. A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development. Nature Cell Biology. doi.org/10.1038/s41556-022-00971-3
2021
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Bingham, M., & Mills, A. Catalytic and photocatalytic water gas shift reaction (WGSR) using a continuous flow, gas phase reactor. Journal of Photochemistry and Photobiology A: Chemistry, doi.org/10.1016/j.jphotochem.2021.113133
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Neils, J. L. D., et al. A plasmonic biosensor array exploiting plasmon coupling between gold nanorods and spheres for domoic acid detection via two methods. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY. doi.org/10.1016/j.saa.2021.119473
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Althobaiti, N. A., et al. Assessment and Validation of Globodera pallida as a Novel In Vivo Model for Studying Alzheimer’s Disease. Cells, doi.org/10.3390/cells10092481
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Brown, R., et al. Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice. Mediators of Inflammation, doi.org/10.1155/2021/6682657
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McErlean, E. M., et al. Rational design and characterisation of a linear cell penetrating peptide for non-viral gene delivery. Journal of Controlled Release, doi.org/10.1016/j.jconrel.2020.11.037
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Ye, Z., et al. Self-assembly of colloidal nanoparticles into 2D arrays at water–oil interfaces: rational construction of stable SERS substrates withaccessible enhancing surfaces and tailored plasmonic response. Nanoscale - Royal Society of Chemistry. doi.org/10.1039/d0nr08803j
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Bennie, L. A., et al. Formulating RALA/Au nanocomplexes to enhance nanoparticle internalisation efficiency, sensitising prostate tumour models to radiation treatment. Journal of nanobiotechnology, doi.org/10.1186/s12951-021-01019-8
- Díez-Aguilar M, et al. Anti-biofilm activity of murepavadin against cystic fibrosis Pseudomonas aeruginosa isolates. J Antimicrob Chemother. doi: 10.1093/jac/dkab222.
- Albadr AA, et al. Rapidly dissolving microneedle patch of amphotericin B for intracorneal fungal infections. Drug Deliv Transl Res. doi: 10.1007/s13346-021-01032-2.
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Angbohang, A., et al. X-box binding protein 1-mediated COL4A1s secretion regulates communication between vascular smooth muscle and stem/progenitor cells. The Journal of biological chemistry,doi.org/10.1016/j.jbc.2021.100541
2020
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Mills, A., & McNeill, A. . CdS-coated thin plastic films for visible-light photocatalysis. Journal of Physics: Energy. doi.org/10.1088/2515-7655/abb927
- Ruiz A, et al. Encapsulated doxorubicin crystals influence lysolipid temperature-sensitive liposomes release and therapeutic efficacy in vitro and in vivo. J Control Release. doi: 10.1016/j.jconrel.2020.09.032.
- Bingham M, Mills A. photonic efficiency and selectivity study of M (M=Pt, Au and Ag)/TiO2 photocatalysts for methanol reforming in the gas phase. Journal of Photochemistry and Photobiology A: Chemistry, doi.org/10.1016/j.photochem.2019.112257