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Publications:

2025

  • Saha C, et al. Development of a nano-vaccine for high-grade serous ovarian cancer. Biomater ci.  doi: 10.1039/d4bm01696c. 
  • Li M, et al. Bimodal Dissolving Microneedles with Nanoparticle Coating and Encapsulation for Extended Dual-Drug Delivery. Small.  doi: 10.1002/smll.202502904. 

  • Chambers SEJ, et al. Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity. Angiogenesis.   doi: 10.1007/s10456-025-09982-8. 
  • Szczepan M, et al. Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci.  doi: 10.1167/iovs.66.3.41. 

  • Hahn H, et al. Endosomal chemokine receptor signalosomes regulate central mechanisms underlying cell migration. Elife.  doi: 10.7554/eLife.99373. 
  • Parau G, et al. Clinical isolates of antimicrobial resistant Enterobacter species can persist in human macrophages without replication and overt cellular cytotoxicity. J Infect Dis.  doi: 10.1093/infdis/jiaf099. 
  • Alotaibi H, Hatahet T, Al-Jamal WT. Understanding the formulation parameters for engineering indocyanine green J-aggregate lipid nanocapsules and solid lipid nanoparticles as promising photothermal agents. Eur J Pharm Sci.  doi: 10.1016/j.ejps.2025.107034. 
  • Pentlavalli S, et al. D-peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention. J Control Release.  doi: 10.1016/j.jconrel.2024.12.052. 
  • Armstrong R, et al. Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development. PLoS Pathog.  doi: 10.1371/journal.ppat.1012562. 

  • Dedeloudi A, et al. Biopolymeric 3D printed scaffolds as a versatile tissue engineering treatment for congenital diaphragmatic hernia. Int J Pharm.  doi: 10.1016/j.ijpharm.2025.125313. 

  • Gade S, Vora LK, Thakur RRS. Design and characterization of hollow microneedles for localized intrascleral drug delivery of ocular formulations. Methods.  doi: 10.1016/j.ymeth.2024.12.004. 
  • Paris JL, et al. Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform. Int J Pharm.   doi: 10.1016/j.ijpharm.2024.125064.

  • Martín-Vicente P, et al. Mechanical Stretch Induces Senescence of Lung Epithelial Cells and Drives Fibroblast Activation by Paracrine Mechanisms. Am J Respir Cell Mol Biol.   doi: 10.1165/rcmb.2023-0449OC. 
  • Al-Jamal WT, et al. Biodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: Formulation, in vitro toxicity and in vivo clearance. Int J Pharm.  doi: 10.1016/j.ijpharm.2024.124963. 

 

2024

  • Ramos H, et al. Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/- rat model. J Neuroinflammation.  doi: 10.1186/s12974-024-03283-5.
  • Brown R, et al. SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease. Front Immunol.  doi: 10.3389/fimmu.2024.1433642. 
  • Naderi-Meshkin H, et al. Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids. Stem Cells.  doi: 10.1093/stmcls/sxae043. 
  • Pathak V, et al. Modulation of diabetes-related retinal pathophysiology by PTX3. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.2320034121. 

  • Faizi HS, Nasiri MI, Wu Y, Mishra D, Donnelly RF, Minhas MU, Vora LK, Singh Thakur RR. Deferasirox nanosuspension loaded dissolving microneedles for ocular drug delivery. Int J Pharm.  doi: 10.1016/j.ijpharm.2024.124614. 
  • Alsa'd AA, et al. Optimising intracellular delivery of antibiotic loaded PLGA nanoparticles to macrophages. Int J Pharm.  doi: 10.1016/j.ijpharm.2024.124567. 

  • Liu X, et al. Non-linear responses via agglomeration and aggregation of gold nanoparticles for surface-enhanced Raman spectroscopy (SERS) coupled with chemometric analysis for chlorpyrifos detection. Food Chem.  doi: 10.1016/j.foodchem.2024.139944. 

  • Carvalho AM, et al. Development of CD33-Targeted Dual Drug-Loaded Nanoparticles for the Treatment of Pediatric Acute Myeloid Leukemia. Biomacromolecules.  doi: 10.1021/acs.biomac.4c00672. 

  • Glass K, et al. Development and Characterization of a Peptide-Bisphosphonate Nanoparticle for the Treatment of Breast Cancer. Mol Pharm.  doi: 10.1021/acs.molpharmaceut.4c00299. 

  • Saha S, et al. Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor. Cell.  doi: 10.1016/j.cell.2024.07.005.  

  • Li Y, Wang J, et al. Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch. J Control Release.  doi: 10.1016/j.jconrel.2024.06.039. 

  • McMillan HP, et al. Immunological isolation and characterization of neuronal progenitors from human dental pulp: A laboratory-based investigation. Int Endod J.  doi: 10.1111/iej.14077. 

  • Miles CM, et al. Unravelling the interactions between small molecules and liposomal bilayers via molecular dynamics and thermodynamic modelling. Int J Pharm.  doi: 10.1016/j.ijpharm.2024.124367. 

  • Dunne VL, et al. PTEN Depletion Increases Radiosensitivity in Response to Ataxia Telangiectasia-Related-3 (ATR) Inhibition in Non-Small Cell Lung Cancer (NSCLC). Int J Mol Sci. doi: 10.3390/ijms25147817.

  • Sushentsev N, et al. Metabolic imaging across scales reveals distinct prostate cancer phenotypes. Nat Commun. doi: 10.1038/s41467-024-50362-5. 

  • Dupont M, et al. The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic Acids Res.  doi: 10.1093/nar/gkae291. 

  • Risseeuw, S., et al. (2024). Bruch's membrane calcification in pseudoxanthoma elasticum: comparing histopathology and clinical imaging. Ophthalmology Science. doi.org/10.1016/j.xops.2023.100416 

  • Li H, Anjani QK, et al. Design of a Novel Delivery Efficiency Feedback System for Biphasic Dissolving Microarray Patches Based on Poly(Lactic Acid) and Moisture-Indicating Silica. Adv Healthc Mater. doi: 10.1002/adhm.202304082. 

  • Qian K, Stella L, Liu F, Jones DS, Andrews GP, Tian Y. Kinetic and Thermodynamic Interplay of Polymer-Mediated Liquid-Liquid Phase Separation for Poorly Water-Soluble Drugs. Mol Pharm. doi: 10.1021/acs.molpharmaceut.4c00033. 

  • Fuster MG, Wang J, Fandiño O, Víllora G, Paredes AJ. Folic Acid-Decorated Nanocrystals as Highly Loaded Trojan Horses to Target Cancer Cells. Mol Pharm.  doi: 10.1021/acs.molpharmaceut.3c01186. 

  • McCusker P, et al. Neoblast-like stem cells of Fasciola hepatica. PLoS Pathog . doi.org/10.1371/journal.ppat.1011903

  • Bonazza S, et al.  Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking. PLoS Pathog. doi.org/10.1371/journal.ppat.1012231

  • McMillan HP, et al. Immunological isolation and characterization of neuronal progenitors from human dental pulp: A laboratory-based investigation. Int Endod J. doi: 10.1111/iej.14077. 

  • Llorián-Salvador M, et al. Regulatory T cells limit age-associated retinal inflammation and neurodegeneration. Mol Neurodegener.  Doi: 10.1186/s13024-024-00724-w. 
  • Demartis S, et al. Improved pharmacokinetic and lymphatic uptake of Rose Bengal after transfersome intradermal deposition using hollow microneedles. J Control Release. doi: 10.1016/j.jconrel.2024.03.048. 
  • Ouyang X, et al. House dust mite allergens induce Ca2+ signalling and alarmin responses in asthma airway epithelial cells. Biochim Biophys Acta Mol Basis Dis.  doi: 10.1016/j.bbadis.2024.167079. 
  • Dallal Bashi YH, et al. Inhaled dry powder liposomal azithromycin for treatment of chronic lower respiratory tract infection. Int J Pharm.  doi: 10.1016/j.ijpharm.2024.123841. 

  • Wilson JJ, et al. Synthesis and characterisation of a nucleotide based pro-drug formulated with a peptide into a nano-chemotherapy for colorectal cancer. J Control Release.  doi: 10.1016/j.jconrel.2024.03.036. 

  • Li H, Anjani QK, et al. Design of a Novel Delivery Efficiency Feedback System for Biphasic Dissolving Microarray Patches Based on Poly(Lactic Acid) and Moisture-Indicating Silica. Adv Healthc Mater.  doi: 10.1002/adhm.202304082. 

  • de la Fuente AG, et al. Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination. Nat Commun.  doi: 10.1038/s41467-024-45742-w. 

  • Roussel S, Udabe J, Bin Sabri A, Calderón M, Donnelly R. Leveraging novel innovative thermos responsive polymers in microneedles for targeted intradermal deposition. Int J Pharm.   doi: 10.1016/j.ijpharm.2024.123847. 

  • Holloway J,et al. The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis. Cell Death Dis.  doi: 10.1038/s41419-023-06417-4. 

  • Anderson A, et al. Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status. Nat Commun.   doi: 10.1038/s41467-024-45387-9. 
  • Smith MR, Naeli P, Jafarnejad SM, Costa G. The scaffolding protein AKAP12 regulates mRNA localization and translation. Proc Natl Acad Sci U S A.  doi: 10.1073/pnas.2320609121. 
  • Dunne OM, et al. TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells. Respir Res. doi: 10.1186/s12931-024-02807-0. 

 

2023

  • Al Natour B, et al. Regulation of caries-induced pulp inflammation by NLRP3 inflammasome: A laboratory-based investigation. Int Endod J.  doi: 10.1111/iej.13855. 
  • McKerr, N., Mohd-Sarip, A., Dorrian, H. et al. CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation. Sci Rep  https://doi.org/10.1038/s41598-023-28693-y

  • Risseeuw S, et al.Bruch's Membrane Calcification in Pseudoxanthoma Elasticum: Comparing Histopathology and Clinical Imaging. Ophthalmol Sci.  doi: 10.1016/j.xops.2023.100416. 
  • Zhang C, et al. Curcumin nanocrystals-in-nanofibres as a promising platform for the management of periodontal disease. Int J Pharm. doi: 10.1016/j.ijpharm.2023.123585.

  • Sadowska JM, et al.. Development of miR-26a-activated scaffold to promote healing of critical-sized bone defects through angiogenic and osteogenic mechanisms. Biomaterials.  doi: 10.1016/j.biomaterials.2023.122398. 

  • Tabaei SR, et al. Recapitulating the Lateral Organization of Membrane Receptors at the Nanoscale. ACS Nano. doi: 10.1021/acsnano.3c00683. 
  • Lou-Franco J, et al. Smartphone-based immunochemical sensor exploiting peroxidase-like activity of ligand-capped gold nanostars: A proof-of-concept detection of Mycobacterium bovis. Biosens Bioelectron. doi: 10.1016/j.bios.2022.114857

  • Bombin ADJ, et al. Delivery of a peptide/microRNA blend via electrospun antimicrobial nanofibres for wound repair. Acta Biomater.  doi: 10.1016/j.actbio.2022.10.059

  • Zhang, Y., Ye, Z., Li, C. et al. General approach to surface-accessible plasmonic Pickering emulsions for SERS sensing and interfacial catalysis. Nat Commun  https://doi.org/10.1038/s41467-023-37001-1
  • Álvarez-Barrios, A., et al.2023. Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium. Frontiers in Nutrition. https://doi.org/10.3389/fnut.2023.1124987 

2022

  • Bianchi MB, et al. Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues. Mater Today Bio.  doi: 10.1016/j.mtbio.2022.100471. 

  • Abd-El-Azim, H., et al. Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer. Journal of controlled release : official journal of the Controlled Release Society,  doi.org/10.1016/j.jconrel.2022.06.027

  • Broadbent, L., et al. An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells. PLoS ONE,  doi.org/10.1371/journal.pone.0266412

  • Dumigan A, et al. In vivo single-cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection. EMBO Mol Med. doi:10.15252/emmm.202216888. 

  • Kurzawa-Akanbi M, et al. Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina. J Extracell Vesicles.  doi: 10.1002/jev2.12295. 

  • Tabel, M., et al. Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration. Journal of Neuroinflammation, 19, [229].
  • Jacobs E, et al. Design and scale-up of amorphous drug nanoparticles production via a one-step anhydrous continuous process. Int J Pharm. doi:10.1016/j.ijpharm.2022.122304  

  • Robb E, et al. Transcriptomic analysis supports a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles. PLoS Negl Trop Dis.   doi: 10.1371/journal.pntd.0010854. 

  • Demartis S, et al. Trilayer dissolving polymeric microneedle array loading Rose Bengal transfersomes as a novel adjuvant in early-stage cutaneous melanoma management. Int J Pharm.  doi: 10.1016/j.ijpharm.2022.122217. 

  • Harkin, K., et al. Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 Pathway. Biomedicines,   doi.org/10.3390/biomedicines10020311

  • O'Hare, M., et al. Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats. JCI insight, 7(18). doi.org/10.1172/jci.insight.155128

  • Tsolaki E, et al. Nuclear and cellular, micro and nano calcification in Alzheimer's disease patients and correlation to phosphorylated Tau. Acta Biomater.  doi: 10.1016/j.actbio.2022.03.003. 

  • Matute-Blanch C, et al. Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non-cell-autonomous neuronal damage. Clin Transl Med.  doi: 10.1002/ctm2.837. 

  • Jia Lin, et al. USP17 is required for peripheral trafficking of lysosomes. EMBO reports. e51932https://doi.org/10.15252/embr.202051932

  • Nasiri, M.I. et al. Nanoemulsion-based dissolving microneedle arrays for enhanced intradermal and transdermal delivery. Drug Deliv. and Transl. Res.  doi.org/10.1007/s13346-021-01107-0
  • Wu, Y., et al.  Nanosuspension-loaded dissolving bilayer microneedles for hydrophobic drug delivery to the posterior segment of the eye. Biomaterials Advances,  doi.org/10.1016/j.bioadv.2022.212767

  • Wu Y, et al. Long-acting nanoparticle-loaded bilayer microneedles for protein delivery to the posterior segment of the eye. Eur J Pharm Biopharm.   doi: 10.1016/j.ejpb.2021.05.022. 

  • Albargothy, M. J., et al. Investigation of heterocellular features of the mouse retinal neurovascular unit by 3D electron microscopy. Journal of Anatomy. doi.org/10.1111/joa.13721

  • Albadr AA, et al. Rapidly dissolving microneedle patch of amphotericin B for intracorneal fungal infections. Drug Deliv Transl Res.  doi: 10.1007/s13346-021-01032-2.  

  • Pereira S, et al. Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy. Acta Biomater. doi: 10.1016/j.actbio.2021.12.019. 

  • Llorián-Salvador, et al. Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells. Journal of Neuroinflammation. doi.org/10.1186/s12974-022-02546-3

  • Bertelli PM, et al. Long term high glucose exposure induces premature senescence in retinal endothelial cells. Frontiers in Physiology,  doi.org/10.3389/fphys.2022.929118

  • Su Y, et al. Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis. Thorax. doi.org/10.1136/thoraxjnl-2021-218194

  • Pereira S. et al. Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy. Acta biomaterialia,  doi.org/10.1016/j.actbio.2021.12.019

  • Reina, G., et al. Design of a graphene oxide-BODIPY conjugate for glutathione depletion and photodynamic therapy. 2D Materials. doi.org/10.1088/2053-1583/ac4572

  • Osbourn  M., et al. Secretory leucoprotease inhibitor (SLPI) promotes survival during acute pseudomonas aeruginosa infection by suppression of inflammation rather than microbial killing. Biomolecules. doi.org/10.3390/biom12121728

  • Sahu, S. K., et al. A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development. Nature Cell Biology. doi.org/10.1038/s41556-022-00971-3

2021

2020